{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T21:25:33Z","timestamp":1760909133644},"reference-count":12,"publisher":"Medwave Estudios Limitada","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medwave"],"DOI":"10.5867\/medwave.2018.03.7211","type":"journal-article","created":{"date-parts":[[2018,7,13]],"date-time":"2018-07-13T15:03:39Z","timestamp":1531494219000},"page":"e7211-e7211","source":"Crossref","is-referenced-by-count":1,"title":["Observational study to analyze patterns of treatment of breakthrough dyspnea in cancer patients in clinical practice"],"prefix":"10.5867","volume":"18","author":[{"given":"Luis","family":"Cabez\u00f3n-Guti\u00e9rrez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Delgado-Mingorance","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Nabal-Vicu\u00f1a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Javier","family":"Jim\u00e9nez-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Cabez\u00f3n-\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bego\u00f1a","family":"Soler-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3888","published-online":{"date-parts":[[2018,6,26]]},"reference":[{"issue":"1","key":"ref0","first-page":"37","article-title":"Characteristics and correlates of dyspnea in patients with advanced cancer. J Palliat Med. 2009 Jan;12(1):29-36. | CrossRef | PubMed | O'Driscoll M, Corner J, Bailey C. The experience of breathlessness in lung cancer.","volume":"8","author":"Reddy","year":"1999","unstructured":"Reddy SK, Parsons HA, Elsayem A, Palmer JL, Bruera E. Characteristics and correlates of dyspnea in patients with advanced cancer. J Palliat Med. 2009 Jan;12(1):29-36. | CrossRef | PubMed | O'Driscoll M, Corner J, Bailey C. The experience of breathlessness in lung cancer. Eur J Cancer Care (Engl). 1999 Mar;8(1):37-43. | PubMed |","journal-title":"Eur J Cancer Care (Engl )","ISSN":"http:\/\/id.crossref.org\/issn\/0961-5423","issn-type":"print"},{"issue":"2","key":"ref1","first-page":"90","article-title":"Episodic breathlessness in patients with advanced disease: a systematic review. J Pain Symptom Manage. 2013 Mar;45(3):561-78. | CrossRef | PubMed | Booth S, Silvester S, Todd C. Breathlessness in cancer and chronic obstructive pulmonary disease: using a qualitative approach to describe the experience of patients and carers. Palliat Support Care. 2003 Dec;1(4):337-44. | PubMed | Lai YL, Chan CW, Lopez V. Perceptions of dyspnea and helpful interventions during the advanced stage of lung cancer: Chinese patients' perspectives. Cancer Nurs. 2007 Mar-Apr;30(2):E1-8. | PubMed | Henoch I, Bergman B, Danielson E. Dyspnea experience and management strategies in patients with lung cancer. Psychooncology. 2008 Jul;17(7):709-15. | PubMed | Ek K, Ternestedt BM. Living with chronic obstructive pulmonary disease at the end of life: a phenomenological study. J Adv Nurs. 2008 May;62(4):470-8. | CrossRef | PubMed | Navigante AH, Cerchietti LC, Castro MA, Lutteral MA, Cabalar ME. Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnea perception in patients with advanced cancer. J Pain Symptom Manage. 2006 Jan;31(1):38-47. | PubMed | Bailey PH. The dyspnea-anxiety-dyspnea cycle--COPD patients' stories of breathlessness: \"It's scary \/when you can't breathe\". Qual Health Res. 2004 Jul;14(6):760-78. | PubMed | Booth S, Moosavi SH, Higginson IJ. The etiology and management of intractable breathlessness in patients with advanced cancer: a systematic review of pharmacological therapy.","volume":"5","author":"Simon","year":"2008","unstructured":"Simon ST, Bausewein C, Schildmann E, Higginson IJ, Magnussen H, Scheve C, et al. Episodic breathlessness in patients with advanced disease: a systematic review. J Pain Symptom Manage. 2013 Mar;45(3):561-78. | CrossRef | PubMed | Booth S, Silvester S, Todd C. Breathlessness in cancer and chronic obstructive pulmonary disease: using a qualitative approach to describe the experience of patients and carers. Palliat Support Care. 2003 Dec;1(4):337-44. | PubMed | Lai YL, Chan CW, Lopez V. Perceptions of dyspnea and helpful interventions during the advanced stage of lung cancer: Chinese patients' perspectives. Cancer Nurs. 2007 Mar-Apr;30(2):E1-8. | PubMed | Henoch I, Bergman B, Danielson E. Dyspnea experience and management strategies in patients with lung cancer. Psychooncology. 2008 Jul;17(7):709-15. | PubMed | Ek K, Ternestedt BM. Living with chronic obstructive pulmonary disease at the end of life: a phenomenological study. J Adv Nurs. 2008 May;62(4):470-8. | CrossRef | PubMed | Navigante AH, Cerchietti LC, Castro MA, Lutteral MA, Cabalar ME. Midazolam as adjunct therapy to morphine in the alleviation of severe dyspnea perception in patients with advanced cancer. J Pain Symptom Manage. 2006 Jan;31(1):38-47. | PubMed | Bailey PH. The dyspnea-anxiety-dyspnea cycle--COPD patients' stories of breathlessness: \"It's scary \/when you can't breathe\". Qual Health Res. 2004 Jul;14(6):760-78. | PubMed | Booth S, Moosavi SH, Higginson IJ. The etiology and management of intractable breathlessness in patients with advanced cancer: a systematic review of pharmacological therapy. Nat Clin Pract Oncol. 2008 Feb;5(2):90-100. | CrossRef | PubMed |","journal-title":"Nat Clin Pract Oncol","ISSN":"http:\/\/id.crossref.org\/issn\/1743-4254","issn-type":"print"},{"issue":"5","key":"ref2","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1007\/s00482-012-1228-3","volume":"26","author":"Simon","year":"2012","unstructured":"Simon ST, K\u00f6skeroglu P, Bausewein C. [Pharmacological therapy of refractory dyspnoea : a systematic literature review]. Schmerz. 2012 Sep;26(5):515-22. | CrossRef | PubMed |","journal-title":"Schmerz","ISSN":"http:\/\/id.crossref.org\/issn\/0932-433X","issn-type":"print"},{"issue":"3","key":"ref3","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1200\/JCO.1984.2.3.187","article-title":"Karnofsky performance status revisited: reliability, validity, and guidelines.","volume":"2","author":"Schag","year":"1984","unstructured":"Schag CC, Heinrich RL, Ganz PA. Karnofsky performance status revisited: reliability, validity, and guidelines. J Clin Oncol. 1984 Mar;2(3):187-93. | PubMed |","journal-title":"J Clin Oncol","ISSN":"http:\/\/id.crossref.org\/issn\/0732-183X","issn-type":"print"},{"issue":"6","key":"ref4","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1378\/chest.85.6.751","article-title":"The measurement of dyspnea. Contents, interobserver agreement, and physiologic correlates of two new clinical indexes.","volume":"85","author":"Mahler","year":"1984","unstructured":"Mahler DA, Weinberg DH, Wells CK, Feinstein AR. The measurement of dyspnea. Contents, interobserver agreement, and physiologic correlates of two new clinical indexes. Chest. 1984 Jun;85(6):751-8. | PubMed |","journal-title":"Chest","ISSN":"http:\/\/id.crossref.org\/issn\/0012-3692","issn-type":"print"},{"issue":"6","key":"ref5","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1249\/00005768-198315060-00015","article-title":"A category-ratio perceived exertion scale: relationship to blood and muscle lactates and heart rate.","volume":"15","author":"Noble","year":"1983","unstructured":"Noble BJ, Borg GA, Jacobs I, Ceci R, Kaiser P. A category-ratio perceived exertion scale: relationship to blood and muscle lactates and heart rate. Med Sci Sports Exerc. 1983;15(6):523-8. | PubMed |","journal-title":"Med Sci Sports Exerc","ISSN":"http:\/\/id.crossref.org\/issn\/0195-9131","issn-type":"print"},{"issue":"2","key":"ref6","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/082585979100700202","article-title":"The Edmonton Symptom Assessment System (ESAS): a simple method for the assessment of palliative care patients.","volume":"7","author":"Bruera","year":"1991","unstructured":"Bruera E, Kuehn N, Miller MJ, Selmser P, Macmillan K. The Edmonton Symptom Assessment System (ESAS): a simple method for the assessment of palliative care patients. J Palliat Care. 1991 Summer;7(2):6-9. | PubMed |","journal-title":"J Palliat Care","ISSN":"http:\/\/id.crossref.org\/issn\/0825-8597","issn-type":"print"},{"issue":"5","key":"ref7","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus.","volume":"12","author":"Fearon","year":"2011","unstructured":"Fearon K, Strasser F, Anker SD, Bosaeus I, Bruera E, Fainsinger RL, et al. Definition and classification of cancer cachexia: an international consensus. Lancet Oncol. 2011 May;12(5):489-95. | CrossRef | PubMed |","journal-title":"Lancet Oncol","ISSN":"http:\/\/id.crossref.org\/issn\/1470-2045","issn-type":"print"},{"issue":"1","key":"ref8","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1164\/ajrccm.159.1.ats898","article-title":"Dyspnea. Mechanisms, assessment, and management: a consensus statement. American Thoracic Society.","volume":"159","year":"1999","unstructured":"Dyspnea. Mechanisms, assessment, and management: a consensus statement. American Thoracic Society. Am J Respir Crit Care Med. 1999 Jan;159(1):321-40. | PubMed |","journal-title":"Am J Respir Crit Care Med","ISSN":"http:\/\/id.crossref.org\/issn\/1073-449X","issn-type":"print"},{"issue":"2","key":"ref9","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.ejon.2007.09.006","article-title":"Dyspnea experience in patients with lung cancer in palliative care.","volume":"12","author":"Henoch","year":"2008","unstructured":"Henoch I, Bergman B, Gustafsson M, Gaston-Johansson F, Danielson E. Dyspnea experience in patients with lung cancer in palliative care. Eur J Oncol Nurs. 2008 Apr;12(2):86-96. | PubMed |","journal-title":"Eur J Oncol Nurs","ISSN":"http:\/\/id.crossref.org\/issn\/1462-3889","issn-type":"print"},{"issue":"1","key":"ref10","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1177\/1054773803238742","article-title":"Acute dyspnea as perceived by patients with chronic obstructive pulmonary disease.","volume":"12","author":"Heinzer","year":"2003","unstructured":"Heinzer MM, Bish C, Detwiler R. Acute dyspnea as perceived by patients with chronic obstructive pulmonary disease. Clin Nurs Res. 2003 Feb;12(1):85-101. | PubMed |","journal-title":"Clin Nurs Res","ISSN":"http:\/\/id.crossref.org\/issn\/1054-7738","issn-type":"print"},{"issue":"4","key":"ref11","first-page":"331","article-title":"Effects of prophylactic subcutaneous fentanyl on exercise-induced breakthrough dyspnea in cancer patients: a preliminary double-blind, randomized, controlled trial. J Pain Symptom Manage. 2014 Feb;47(2):209-17. | CrossRef | PubMed | Hui D, Kilgore K, Park M, Williams J, Liu D, Bruera E. Impact of Prophylactic Fentanyl Pectin Nasal Spray on Exercise-Induced Episodic Dyspnea in Cancer Patients: A Double-Blind, Randomized Controlled Trial. J Pain Symptom Manage. 2016 Oct;52(4):459-468.e1. | CrossRef | PubMed | Davies AN, Dickman A, Reid C, Stevens AM, Zeppetella G; Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. The management of cancer-related breakthrough pain: recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland.","volume":"13","author":"Navigante","year":"2009","unstructured":"Navigante AH, Castro MA, Cerchietti LC. Morphine versus midazolam as upfront therapy to control dyspnea perception in cancer patients while its underlying cause is sought or treated. J Pain Symptom Manage. 2010 May;39(5):820-30. | CrossRef | PubMed | Abernethy AP, Currow DC, Frith P, Fazekas BS, McHugh A, Bui C. Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea. BMJ. 2003 Sep 6;327(7414):523-8. | PubMed | Lacasse Y, Goldstein R, Lasserson TJ, Martin S. Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD003793. | PubMed | Hui D, Xu A, Frisbee-Hume S, Chisholm G, Morgado M, Reddy S, et al. Effects of prophylactic subcutaneous fentanyl on exercise-induced breakthrough dyspnea in cancer patients: a preliminary double-blind, randomized, controlled trial. J Pain Symptom Manage. 2014 Feb;47(2):209-17. | CrossRef | PubMed | Hui D, Kilgore K, Park M, Williams J, Liu D, Bruera E. Impact of Prophylactic Fentanyl Pectin Nasal Spray on Exercise-Induced Episodic Dyspnea in Cancer Patients: A Double-Blind, Randomized Controlled Trial. J Pain Symptom Manage. 2016 Oct;52(4):459-468.e1. | CrossRef | PubMed | Davies AN, Dickman A, Reid C, Stevens AM, Zeppetella G; Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. The management of cancer-related breakthrough pain: recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. Eur J Pain. 2009 Apr;13(4):331-8. | CrossRef | PubMed |","journal-title":"Eur J Pain","ISSN":"http:\/\/id.crossref.org\/issn\/1090-3801","issn-type":"print"}],"container-title":["Medwave"],"original-title":[],"link":[{"URL":"https:\/\/www.medwave.cl\/link.cgi\/Medwave\/Estudios\/Investigacion\/7211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,20]],"date-time":"2019-10-20T19:49:31Z","timestamp":1571600971000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.medwave.cl\/link.cgi\/English\/Original\/Research\/7212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,26]]},"references-count":12,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2018,6,26]]}},"URL":"https:\/\/doi.org\/10.5867\/medwave.2018.03.7211","relation":{},"ISSN":["0717-6384"],"issn-type":[{"value":"0717-6384","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,26]]}}}