{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T18:55:39Z","timestamp":1762023339434,"version":"build-2065373602"},"reference-count":9,"publisher":"Medwave Estudios Limitada","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medwave"],"DOI":"10.5867\/medwave.2020.05.7732","type":"journal-article","created":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T21:48:00Z","timestamp":1592603280000},"page":"e7732-e7732","source":"Crossref","is-referenced-by-count":4,"title":["Ibuprofen versus acetazolamide for prevention of acute mountain sickness"],"prefix":"10.5867","volume":"20","author":[{"given":"Maximilian","family":"Schilling","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebasti\u00e1n","family":"Irarr\u00e1zaval","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3888","published-online":{"date-parts":[[2020,6,15]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Nieto Estrada VH, Molano Franco D, Medina RD, Gonzalez Garay AG, Mart\u00ed-Carvajal AJ, Arevalo-Rodriguez I. Interventions for preventing high altitude illness: Part 1. Commonly-used classes of drugs. Cochrane Database Syst Rev. 2017 Jun 27;6:CD009761. | CrossRef | PubMed | PMC |","DOI":"10.1002\/14651858.CD009761.pub2"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"Sridharan K, Sivaramakrishnan G. Pharmacological interventions for preventing acute mountain sickness: a network meta-analysis and trial sequential analysis of randomized clinical trials. Ann Med. 2018 Mar;50(2):147-155. | CrossRef | PubMed |","DOI":"10.1080\/07853890.2017.1407034"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Gertsch JH, Lipman GS, Holck PS, Merritt A, Mulcahy A, Fisher RS, Basnyat B, Allison E, Hanzelka K, Hazan A, Meyers Z, Odegaard J, Pook B, Thompson M, Slomovic B, Wahlberg H, Wilshaw V, Weiss EA, Zafren K. Prospective, double-blind, randomized, placebo-controlled comparison of acetazolamide versus ibuprofen for prophylaxis against high altitude headache: the Headache Evaluation at Altitude Trial (HEAT). Wilderness Environ Med. 2010 Sep;21(3):236-43. | CrossRef | PubMed |","DOI":"10.1016\/j.wem.2010.06.009"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Gertsch JH, Corbett B, Holck PS, Mulcahy A, Watts M, Stillwagon NT, Casto AM, Abramson CH, Vaughan CP, Macguire C, Farzan NN, Vo BN, Norvelle RJ, May K, Holly JE, Irons H, Stutz AM, Chapagain P, Yadav S, Pun M, Farrar J, Basnyat B. Altitude Sickness in Climbers and Efficacy of NSAIDs Trial (ASCENT): randomized, controlled trial of ibuprofen versus placebo for prevention of altitude illness. Wilderness Environ Med. 2012 Dec; 23(4):307-15. | CrossRef | PubMed |","DOI":"10.1016\/j.wem.2012.08.001"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Lipman GS, Kanaan NC, Holck PS, Constance BB, Gertsch JH; PAINS Group. Ibuprofen prevents altitude illness: a randomized controlled trial for prevention of altitude illness with nonsteroidal anti-inflammatories. Ann Emerg Med. 2012 Jun;59(6):484-90. | CrossRef | PubMed |","DOI":"10.1016\/j.annemergmed.2012.01.019"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Kanaan NC, Peterson AL, Pun M, Holck PS, Starling J, Basyal B, Freeman TF, Gehner JR, Keyes L, Levin DR, O'Leary CJ, Stuart KE, Thapa GB, Tiwari A, Velgersdyk JL, Zafren K, Basnyat B. Prophylactic Acetaminophen or Ibuprofen Results in Equivalent Acute Mountain Sickness Incidence at High Altitude: A Prospective Randomized Trial. Wilderness Environ Med. 2017 Jun;28(2):72-78. | CrossRef | PubMed |","DOI":"10.1016\/j.wem.2016.12.011"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Luks AM, Auerbach PS, Freer L, Grissom CK, Keyes LE, McIntosh SE, Rodway GW, Schoene RB, Zafren K, Hackett PH. Wilderness Medical Society Practice Guidelines for the Prevention and Treatment of Acute Altitude Illness: 2019 Update. | CrossRef | PubMed |","DOI":"10.1016\/j.wem.2019.04.006"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Luks AM, McIntosh SE, Grissom CK, Auerbach PS, Rodway GW, Schoene RB, Zafren K, Hackett PH; Wilderness Medical Society. Wilderness Medical Society practice guidelines for the prevention and treatment of acute altitude illness: 2014 update. Wilderness Environ Med. 2014 Dec;25(4 Suppl):S4-14. | CrossRef | PubMed |","DOI":"10.1016\/j.wem.2014.06.017"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Burns P, Lipman GS, Warner K, Jurkiewicz C, Phillips C, Sanders L, Soto M,Hackett P. Altitude Sickness Prevention with Ibuprofen Relative to Acetazolamide. Am J Med. 2019 eb;132(2):247-251. | CrossRef | PubMed |","DOI":"10.1016\/j.amjmed.2018.10.021"}],"container-title":["Medwave"],"original-title":["Ibuprofeno comparado con acetazolamida para prevenci\u00f3n de mal agudo de monta\u00f1a"],"deposited":{"date-parts":[[2020,8,18]],"date-time":"2020-08-18T12:59:08Z","timestamp":1597755548000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medwave.cl\/link.cgi\/English\/Updates\/Epistemonikos\/7732.act"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,15]]},"references-count":9,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2020,6,15]]}},"URL":"https:\/\/doi.org\/10.5867\/medwave.2020.05.7732","relation":{},"ISSN":["0717-6384"],"issn-type":[{"type":"electronic","value":"0717-6384"}],"subject":[],"published":{"date-parts":[[2020,6,15]]}}}