{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T13:56:55Z","timestamp":1747231015024,"version":"3.40.5"},"reference-count":0,"publisher":"Medwave Estudios Limitada","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medwave"],"abstract":"<jats:p>Lipsch\u00fctz ulcer is a non-sexually transmitted genital lesion of unknown etiology, which presents as a painful vulvar ulcer. Lipsch\u00fctz ulcers have been described in most continents. This is the first case reported in Peru and South America. We present the case of a 33-year-old female patient with a Lipsch\u00fctz ulcer after being vaccinated with the second dose of the AstraZeneca COVID-19 vaccine. She reported having had only one sexual partner in her lifetime. Laboratory results were negative for herpes simplex 2, Cytomegalovirus, Toxoplasma gondii, Epstein-Barr virus, and syphilis. The patient received symptomatic treatment. Ten days after the onset, the patient was significantly better during follow-up. This case report displays a potential adverse effect of the AstraZeneca COVID-19 vaccine as a Lipsch\u00fctz ulcer triggered by the host humoral immune response. However, further research is needed to establish the causal relationship between these two.<\/jats:p>","DOI":"10.5867\/medwave.2023.02.2674","type":"journal-article","created":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T16:49:02Z","timestamp":1680281342000},"page":"e2674-e2674","source":"Crossref","is-referenced-by-count":0,"title":["\u00dalcera vulvar aguda de Lipsch\u00fctz relacionada con la vacunaci\u00f3n por COVID-19: primer caso notificado en Sudam\u00e9rica"],"prefix":"10.5867","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4073-0521","authenticated-orcid":false,"given":"Lucero","family":"Sangster-Carrasco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4073-0521","authenticated-orcid":false,"given":"Paz-Temoche","family":"Romario","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4916-8205","authenticated-orcid":false,"given":"Coronado-Arroyo","family":"Julia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9719-1875","authenticated-orcid":false,"given":"Concepci\u00f3n-Zavaleta","family":"Marcio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4660-0752","authenticated-orcid":false,"given":"Roseboom","family":"Pela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0462-3101","authenticated-orcid":false,"given":"Concepci\u00f3n-Urteaga","family":"Luis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3888","published-online":{"date-parts":[[2023,3,22]]},"container-title":["Medwave"],"original-title":["Lipschu\u0308tz acute vulvar ulcer related to COVID-19 vaccination: First case report in South America"],"deposited":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T16:49:03Z","timestamp":1680281343000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medwave.cl\/investigacion\/casos\/2674.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,22]]},"references-count":0,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2023,3,22]]}},"URL":"https:\/\/doi.org\/10.5867\/medwave.2023.02.2674","relation":{},"ISSN":["0717-6384"],"issn-type":[{"type":"electronic","value":"0717-6384"}],"subject":[],"published":{"date-parts":[[2023,3,22]]}}}