{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T13:28:17Z","timestamp":1786973297917,"version":"build-2736575974"},"reference-count":0,"publisher":"GN1 Sistemas e Publicacoes Ltd.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ABO"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>Purpose: To compare clinical outcomes associated with different intraoperative mitomycin C exposure\ntimes during photorefractive keratectomy for myopia and astigmatism correction. Methods: This prospective,\ncomparative, contralateral-eye study included 41 patients (82 eyes), comprising 28 eyes with\nablation &lt;60\u03bcm and 13 eyes with ablation &gt;60\u03bcm, who underwent photorefractive keratectomy with\nvarying mitomycin C application times based on ablation depth. In eyes with ablation &lt;60\u03bcm, mitomycin\nC was applied for 15 s in one eye and 30 s in the fellow eye. In eyes with ablation &gt;60\u03bcm, mitomycin C\nwas applied for 30 s in one eye and 60 s in the fellow eye. Outcomes included visual acuity, postoperative\npain (visual analog scale), subjective tearing, corneal haze, and refractive results at 3 months. Results:\nNo statistically significant differences were observed between mitomycin C application times within\neither group for postoperative pain, tearing, visual acuity, refractive outcomes (spherical, cylindrical,\nand spherical equivalent), or haze prevalence (p&gt;0.05 for all comparisons). Visual acuity improved in all\ngroups, and no eyes lost \u22652 lines of corrected distance visual acuity. Conclusions: Shorter mitomycin C\nexposure times (15 or 30 s) appear to be as effective and safe as longer durations (30 or 60 s) for haze\nprevention after photorefractive keratectomy without compromising refractive outcomes or increasing\npostoperative discomfort at 3-month follow-up.<\/jats:p>","DOI":"10.5935\/0004-2749.2025-0313","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T13:01:32Z","timestamp":1786971692000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["Effect of mitomycin C exposure time on refractive results, pain, and corneal haze after photorefractive keratectomy"],"prefix":"10.5935","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7658-1564","authenticated-orcid":false,"given":"Paula Virginia Brom dos Santos","family":"Soares","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4405-170X","authenticated-orcid":false,"given":"Elisa Moya","family":"Kazmarek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7236-9538","authenticated-orcid":false,"given":"Elisabeth Brandao","family":"Guimaraes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1865-0337","authenticated-orcid":false,"given":"Marizilda Rita","family":"de Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9942-8583","authenticated-orcid":false,"given":"Renato","family":"Giovedi Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4441-4304","authenticated-orcid":false,"given":"Bernardo Kaplan","family":"Moscovici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3948","published-online":{"date-parts":[[2026]]},"container-title":["Arquivos Brasileiros de Oftalmologia"],"original-title":[],"link":[{"URL":"https:\/\/www.scielo.br\/j\/abo\/a\/XYg8Kqn8VfRmH57pqftQwdC\/?lang=en&ilang=en","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T13:01:34Z","timestamp":1786971694000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.scielo.br\/j\/abo\/a\/XYg8Kqn8VfRmH57pqftQwdC\/?lang=en&ilang=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026]]},"published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.5935\/0004-2749.2025-0313","relation":{},"ISSN":["0004-2749"],"issn-type":[{"value":"0004-2749","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]}}}