{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:45:22Z","timestamp":1792172722826,"version":"4.4.0"},"reference-count":0,"publisher":"GN1 Sistemas e Publicacoes Ltd.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ABO"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>Purpose: To evaluate ocular findings in children born to mothers who were infected with severe\nacute respiratory syndrome coronavirus 2 (SARS-CoV-2) during pregnancy. Methods: This prospective\nobservational study was conducted in Bras\u00edlia, Brazil, between October 2020 and 2021. Children born\nto mothers with laboratory-confirmed SARS-CoV-2 infection during pregnancy were included and\ncompared with a control group of nonexposed children. All participants underwent a comprehensive\nophthalmological examination performed by pediatric ophthalmologists, including assessment of\nocular motility, slit-lamp biomicroscopy, cycloplegic refraction, intraocular pressure measurement,\ncentral corneal pachymetry, indirect ophthalmoscopy, and retinal imaging. Maternal and neonatal\nclinical data were also collected. Ocular parameters were compared between the exposed and control\ngroups. Results: A total of 84 children were evaluated, including 70 exposed to maternal SARS-CoV-2\ninfection and 14 nonexposed controls. The mean gestational age was 38.3\u00b11.8 weeks, and the mean\nbirth weight was 3,192\u00b1492 g. No significant differences were observed between the groups in\nterms of ocular motility, anterior or posterior segment findings, intraocular pressure, central corneal\nthickness, or refractive status. Isolated findings, including epicanthus and congenital ptosis, were\nobserved in a small number of children but were not significantly associated with maternal SARS-CoV-2\ninfection. Conclusions: In this prospective cohort, no significant ocular abnormalities were identified\nin children exposed in utero to maternal SARS-CoV-2 infection compared with nonexposed controls.\nHowever, the relatively small and unbalanced control group limits the strength of these findings,\nwhich should not be interpreted as evidence that maternal SARS-CoV-2 infection does not affect ocular\ndevelopment. Larger prospective studies with adequately sized and balanced comparison groups are\nwarranted to further investigate the potential ocular effects of prenatal SARS-CoV-2 exposure.<\/jats:p>","DOI":"10.5935\/0004-2749.2026-0019","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:54:00Z","timestamp":1792169640000},"page":"1-6","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of ocular manifestations in children born to mothers infected with SARS-CoV-2 during pregnancy"],"prefix":"10.5935","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3693-1934","authenticated-orcid":false,"given":"N\u00fabia Vanessa dos Anjos","family":"Lima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7893-7819","authenticated-orcid":false,"given":"Adriana Sobral","family":"Louren\u00e7o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2218-8018","authenticated-orcid":false,"given":"Ana Carolina Britto Garcia Rocha","family":"Vidal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9453-6767","authenticated-orcid":false,"given":"Nara Lidia Vieira","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7142-5055","authenticated-orcid":false,"given":"Marcos","family":"Balbino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5183-1216","authenticated-orcid":false,"given":"Regina Cele Silveira","family":"Seixas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4347-8886","authenticated-orcid":false,"given":"Geraldo Magela","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6699-291X","authenticated-orcid":false,"given":"Lizandra Moura Paravidine","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0084-736X","authenticated-orcid":false,"given":"Maria Regina","family":"Chalita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3948","published-online":{"date-parts":[[2026]]},"container-title":["Arquivos Brasileiros de Oftalmologia"],"original-title":[],"link":[{"URL":"https:\/\/www.scielo.br\/j\/abo\/a\/w6JB7VYkMfVh66jC9fQnqjH\/?lang=en&ilang=pt_BR","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:54:07Z","timestamp":1792169647000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.scielo.br\/j\/abo\/a\/w6JB7VYkMfVh66jC9fQnqjH\/?lang=en&ilang=pt_BR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026]]},"published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.5935\/0004-2749.2026-0019","relation":{},"ISSN":["0004-2749"],"issn-type":[{"value":"0004-2749","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]}}}