{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:53:53Z","timestamp":1791309233431,"version":"4.3.1"},"reference-count":0,"publisher":"GN1 Sistemas e Publicacoes Ltd.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBRA"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>Objective: To investigate whether post-warming blastocyst morphometric dynamics assessed by time-lapse imaging (TLI) are associated with implantation in intracytoplasmic sperm injection cycles with deferred embryo transfer.\nMethods: This observational cohort study included 822 vitrified-warmed high-quality blastocysts with known implantation outcomes, evaluated between January and October 2024 at a private university-affiliated in vitro fertilization centre. Post-warming morphometric parameters were recorded during a 4-hour incubation period, including initial blastocyst area, maximum blastocyst area (MXBA), initial zona pellucida thickness, minimum zona pellucida thickness (MZP), and blastocyst re-expansion. Associations with implantation were assessed using multivariable logistic regression. A composite weighted score incorporating MXBA, MZP, and blastocyst re-expansion was developed from the regression coefficients and analysed as a continuous variable. Restricted cubic spline modelling was used to assess potential non-linear associations.\nResults: MXBA (OR=1.078; 95% CI 1.029-1.198; p=0.048), MZP (OR=0.923; 95% CI 0.856-0.995; p=0.038), and blastocyst re-expansion (OR=1.183; 95% CI 1.010-1.386; p=0.036) were independently associated with implantation. Each one-standard-deviation increase in the composite weighted score was associated with a 21.6% increase in the odds of implantation (OR=1.216; 95% CI 1.055-1.403; p=0.007). Spline analysis showed a progressive increase in implantation probability across the score range, without strong evidence of non-linearity.\nConclusion: Quantitative post-warming morphometric assessment provides clinically relevant information on blastocyst implantation potential. A composite score integrating MXBA, MZP, and blastocyst re-expansion may support embryo selection in frozen-thawed embryo transfer cycles.<\/jats:p>","DOI":"10.5935\/1518-0557.20260067","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:33:15Z","timestamp":1791307995000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["The predictive value of post-warming morphometric changes parameters for embryo implantation"],"prefix":"10.5935","volume":"30","author":[{"given":"Edson","family":"Borges Jr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Setti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Cavagnoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assumpto","family":"Iaconelli Jr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maite","family":"del Collado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Braga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3948","published-online":{"date-parts":[[2026]]},"container-title":["JBRA Assisted Reproduction"],"original-title":[],"link":[{"URL":"https:\/\/www.jbra.com.br\/trab\/pub\/download_trabalho.php?fileSource=\/var\/www\/vhosts\/jbra.com.br\/media\/trab\/arq_8796&fileName=3471.pdf&id_trabalho=3337","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:33:18Z","timestamp":1791307998000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jbra.com.br\/trab\/pub\/download_trabalho.php?fileSource=\/var\/www\/vhosts\/jbra.com.br\/media\/trab\/arq_8796&fileName=3471.pdf&id_trabalho=3337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"URL":"https:\/\/doi.org\/10.5935\/1518-0557.20260067","relation":{},"ISSN":["1518-0557"],"issn-type":[{"value":"1518-0557","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]}}}