{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T21:12:42Z","timestamp":1772226762308,"version":"3.50.1"},"reference-count":26,"publisher":"Centre for Evaluation in Education and Science (CEON\/CEES)","issue":"2","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/BY\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Biochemistry"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>Background: To systematically evaluate the curative effect of Kanglaite Injection (KLT) in treating pancreatic cancer (PC) by retrospective analysis. Methods: The clinical data of 172 patients with pancreatic cancer were analyzed, and the therapeutic effect, survival time and tumour markers of patients receiving Kanglaite injection combined with conventional chemotherapy were compared with those receiving conventional chemotherapy. Results: The univariate results showed that the two groups had WBC, LY#, MO#, NE#, ALB, FFA, CA199, CA125 in age, sex, tumour site, stage of pancreatic cancer, radiotherapy and metastasis, and laboratory indexes. Multivariate analysis showed that using KLT in pancreatic cancer patients was significantly related to gender and survival outcome, and KLT could prolong the survival of PC patients. In addition, the Chi-square test showed that patients with KLT could reduce the influence on monocyte count and albumin abnormality, which suggested that patients with KLT could reduce adverse reactions. Conclusions: Kanglaite injection combined with conventional radiotherapy and chemotherapy plays a significant role in improving therapeutic effect, immune function, and prolonging survival expression, and it will not increase the incidence of severe adverse reactions.<\/jats:p>","DOI":"10.5937\/jomb0-55284","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T08:07:52Z","timestamp":1761206872000},"page":"447-454","source":"Crossref","is-referenced-by-count":0,"title":["Retrospective analysis of the curative effect of Kanglaite injection on pancreatic cancer"],"prefix":"10.5937","volume":"45","author":[{"given":"Xian","family":"Miao","sequence":"first","affiliation":[{"name":"Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Department of Oncology, Nantong, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu","family":"Dong","sequence":"additional","affiliation":[{"name":"Fudan University Shanghai Cancer Center, Department of Integrative Oncology, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Department of Oncology, Guangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolin","family":"Wen","sequence":"additional","affiliation":[{"name":"Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Department of Oncology, Nantong, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jikai","family":"Ruan","sequence":"additional","affiliation":[{"name":"Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Department of Oncology, Nantong, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawei","family":"Qiao","sequence":"additional","affiliation":[{"name":"Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Department of Oncology, Nantong, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongjuan","family":"Ji","sequence":"additional","affiliation":[{"name":"Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Department of Oncology, Nantong, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei","family":"Cao","sequence":"additional","affiliation":[{"name":"Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Department of Oncology, Nantong, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuijie","family":"Shen","sequence":"additional","affiliation":[{"name":"Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Department of Oncology, Nantong, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3964","reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Islami F Ward EM, Sung H, Cronin KA, Tangka FKL, Sherman RL, Zhao J, Anderson RN, Henley SJ, Yabroff KR et al. 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