{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T15:13:06Z","timestamp":1776265986434,"version":"3.50.1"},"reference-count":42,"publisher":"Centre for Evaluation in Education and Science (CEON\/CEES)","issue":"4","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/BY\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Biochemistry"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>Background: To analyse the correlations between the levels of serum intestinal fatty acid binding protein (I-FABP), D-lactic acid (D-Lac), and intercellular adhesion factor-1 (ICAM-1) in patients with sepsis complicated with intestinal ischemia-reperfusion injury and the degree of intestinal mucosal injury and patient prognosis. Methods: A total of 236 patients with sepsis complicated with intestinal ischemia-reperfusion injury were included in the reperfusion injury group, and 176 patients with sepsis alone during the same period were included in the sepsis group. Based on the extent of intestinal mucosal damage, individuals in the reperfusion injury group were split into three groups: mild injury (52 patients), moderate injury (116 patients), and severe injury (68 patients). The patients were further divided into a good prognosis group (188 patients) and a poor prognosis group (48 patients). The general clinical data of all patients, including laboratory test indicators, were collected and grouped for comparison before and after treatment. Correlation analysis was conducted via Spearman correlation analysis. Predictive value assessment was conducted via receiver operating characteristic (ROC) curves. Results: The reperfusion damage group had higher levels of I-FABP D-Lac, ICAM-1, and IMA than the sepsis alone group, whereas the GLP-1 level was lower (P&amp;lt; 0.05) than the sepsis alone group. Before treatment, the levels of I-FABP D-Lac, ICAM-1, and IMA in the mild, moderate, and severe injury groups increased successively, and the level of GLP-1 decreased successively (P&amp;lt; 0.05). After treatment, the levels of I-FABP D-Lac, ICAM-1, and IMA in the three groups of patients were all lower than those before treatment in the same group, and the levels of the above indicators in the severe injury group were all greater than those in the mild and moderate injury groups during the same period. The GLP-1 levels of the three patient groups were all higher than those before treatment within the same group. In comparison to the mild and moderate damage groups, the severe injury group's GLP-1 levels were lower during the same time period (P&amp;lt; 0.05). Spearman correlation analysis revealed that the levels of I-FABP D-Lac, ICAM-1, and IMA were positively correlated with the AGI grade. In contrast, the level of GLP-1 was negatively correlated with the AGI grade (P&amp;lt; 0.05). While the level of GLP-1 was lower than that of the good prognosis group (P&amp;lt; 0.05), the levels of I-FABP D-Lac, ICAM-1, and IMA were higher in the bad prognosis group. The ROC curve analysis revealed that the combined predictive value of I-FABP D-Lac, ICAM-1, IMA, and GLP-1 for poor prognosis in patients with sepsis complicated by intestinal ischemia-reperfusion injury was greater than that of these five indicators alone (P&amp;lt; 0.05). Conclusions: The levels of serum I-FABP, D-Lac, ICAM-1, IMA, and GLP-1 in patients with sepsis complicated with intestinal ischemia-reperfusion injury are closely related to the degree of intestinal mucosal injury and prognosis. The combined prediction of short-term prognosis has high clinical value.<\/jats:p>","DOI":"10.5937\/jomb0-61181","type":"journal-article","created":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T07:29:07Z","timestamp":1760340547000},"page":"757-766","source":"Crossref","is-referenced-by-count":0,"title":["Correlation analysis of serum intestinal fatty acid binding protein, D-lactic acid and intercellular adhesion factor-1 in sepsis patients with intestinal ischemia"],"prefix":"10.5937","volume":"45","author":[{"given":"Yujie","family":"Shu","sequence":"first","affiliation":[{"name":"Yinzhou District Second Hospital, Department of Gastroenterology, Ningbo City, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Lao","sequence":"additional","affiliation":[{"name":"Yinzhou District Second Hospital, Department of Gastroenterology, Ningbo City, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhangzhang","family":"Song","sequence":"additional","affiliation":[{"name":"Yinzhou District Second Hospital, Department of Gastroenterology, Ningbo City, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhixing","family":"Zhuang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Fujian Medical University, Laboratory Department, Fuzhou City, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongzhang","family":"Li","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Fujian Medical University, Laboratory Department, Fuzhou City, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3964","reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Tang AL, Shen MJ, Zhang GQ. Intestinal microcirculation dysfunction in sepsis: pathophysiology, clinical monitoring, and therapeutic interventions. World J Emerg Med 2022; 13(5): 343-8. doi: 10.5847\/wjem.j.1920-8642.2022.031. PMID: 36119779; PMCID: PMC9420662;","DOI":"10.5847\/wjem.j.1920-8642.2022.031"},{"key":"#cr-split#-ref2.1","doi-asserted-by":"crossref","unstructured":"Liu X, Liu Y, Su X, Jiang L, Tang G, Wang Y. Geranyl-geranylacetone mitigates sepsis-associated intestinal injury through CHIP-dependent anti-inflammation and antioxidative effect. Int Immunopharmacol 2024 Jun 30","DOI":"10.1016\/j.intimp.2024.112263"},{"key":"#cr-split#-ref2.2","doi-asserted-by":"crossref","unstructured":"135: 112263. doi: 10.1016\/j.intimp.2024.112263. Epub 2024 May 23. PMID: 38788444;","DOI":"10.1016\/j.intimp.2024.112263"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Kiwit A, Lu Y, Lenz M, Knopf J, Mohr C, Ledermann Y, Klinke-Petrowsky M, Pagerols Raluy L, Reinshagen K, Herrmann M, Boettcher M, Elrod J. The Dual Role of Neutrophil Extracellular Traps (NETs) in Sepsis and Ischemia Reperfusion Injury: Comparative Analysis across Murine Models. Int J Mol Sci 2024 Mar 28; 25(7): 3787. doi: 10.3390\/ijms25073787. PMID: 38612596; PMCID: PMC11011604;","DOI":"10.3390\/ijms25073787"},{"key":"ref4","unstructured":"Chi H, Wang H, Li Q, Lian Z, Zhang C, Zhang S, Hu D. Prognostic value of serum sodium variability within 72 hours and lactic acid combined with severity score in patients with sepsis. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2023 May; 35(5): 458-62. Chinese. doi: 10.3760\/cma.j.cn121430-20221104-00966. PMID: 37308223;"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Hao X, Guo D, Yuan X, Xu B. The predictive value of cystatin C combined with lactic acid and uric acid in the occurrence of acute kidney injury in sepsis. Clin Nephrol 2022 Jan; 97(1): 60-2. doi: 10.5414\/CN110707. PMID: 34672253;","DOI":"10.5414\/CN110707"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Wu L, Li X, Yan J. Commentary: Machine learning developed an intratumor heterogeneity signature for predicting prognosis and immunotherapy benefits in cholangiocarcinoma. Transl Oncol 2024 Jul; 45: 101995. doi: 10.1016\/j.tranon.2024.101995. Epub 2024 May 9. PMID: 38789241;","DOI":"10.1016\/j.tranon.2024.101995"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Gao Z, Liu YY, Chen YM, Dong JC. Traditional chinese medicine pattern classification and herbal medicine for COVID-19: A comparative study of data from different sources. World J Tradit Chin Med 2023; 9: 81-93. doi: 10.4103\/2311-8571.351792;","DOI":"10.4103\/2311-8571.351792"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Shi Y, Liu YF, Wang JM, Jiang J, He BL, Mu GH, et al. Rhizoma drynariae improves endometrial receptivity in a Mus model of dysfunctional embryo implantation. World J Tradit Chin Med 2023; 9: 94-100. doi: 10.4103\/wjtcm.wjtcm_17_22;","DOI":"10.4103\/wjtcm.wjtcm_17_22"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Chang X, Guo Y, Wang J, Liu J, Ma Y, Lu Q, Han Y. Heart-type fatty acid binding protein (H-FABP) as an early biomarker in sepsis-induced cardiomyopathy: a prospective observational study. Lipids Health Dis 2024 Sep 4; 23(1): 283. doi: 10.1186\/s12944-024-02264-0. PMID: 39232765; PMCID: PMC11373395;","DOI":"10.1186\/s12944-024-02264-0"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Liang S, Xing M, Chen X, Peng J, Song Z, Zou W. Predicting the prognosis in patients with sepsis by a pyroptosis-related gene signature. Front Immunol 2022 Dec 21; 13: 1110602. doi: 10.3389\/fimmu.2022.1110602. PMID: 36618365; PMCID: PMC9811195;","DOI":"10.3389\/fimmu.2022.1110602"},{"key":"ref11","unstructured":"Liu X, Zhao Y, Qin Y, Ma Q, Wang Y, Weng Z, Zhu F. Correlation between blood pressure indexes and prognosis in sepsis patients: a cohort study based on MIMIC-III database. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2023 Jun; 35(6): 578-85. Chinese. doi: 10.3760\/cma.j.cn121430-20220830-00799. PMID: 37366122;"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Wu L, Zheng Y, Liu J, Luo R, Wu D, Xu P, Wu D, Li X. Comprehensive evaluation of the efficacy and safety of LPV\/r drugs in the treatment of SARS and MERS to provide potential treatment options for COVID-19. Aging (Albany NY) 2021 Apr 20; 13(8): 10833-52. doi: 10.18632\/aging.202860. Epub 2021 Apr 20. PMID: 33879634; PMCID: PMC8109137;","DOI":"10.18632\/aging.202860"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Li L, Chen L, Wang H, Li P, Wang D, Zhang W, Mi L, Lin F, Qin Y, Zhou Y. Clinical correlation between coagulation disorders and sepsis in patients with liver failure. Clin Hemorheol Microcirc 2022; 80(3): 219-31. doi: 10.3233\/CH-211113. PMID: 34719481;","DOI":"10.3233\/CH-211113"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Wang J, Feng Q, Wu Y, Wang H. Involvement of blood lncRNA UCA1 in sepsis development and prognosis, and its correlation with multiple inflammatory cytokines. J Clin Lab Anal 2022 Jun; 36(6): e24392. doi: 10.1002\/jcla.24392. Epub 2022 Apr 20. PMID: 35441408; PMCID: PMC9169193;","DOI":"10.1002\/jcla.24392"},{"key":"#cr-split#-ref15.1","doi-asserted-by":"crossref","unstructured":"Jing Y, Wu Y. A Correlation Analysis of Early Sepsis Recognition and Patient Prognosis: A Single-Center Retrospective Study. Br J Hosp Med (Lond) 2025 Jul 25","DOI":"10.12968\/hmed.2025.0166"},{"key":"#cr-split#-ref15.2","doi-asserted-by":"crossref","unstructured":"86(7): 1-12. doi: 10.12968\/hmed.2025.0166. Epub 2025 Jul 22. PMID: 40705547;","DOI":"10.12968\/hmed.2025.0166"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Min J, Lu J, Zhong L, Yuan M, Xu Y. The correlation study between blood urea nitrogen to serum albumin ratio and prognosis of patients with sepsis during hospitalization. BMC Anesthesiol 2022 Dec 28; 22(1): 404. doi: 10.1186\/s12871-022-01947-4. PMID: 36577937; PMCID: PMC9795581;","DOI":"10.1186\/s12871-022-01947-4"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Wu L, Zhong Y, Wu D, Xu P, Ruan X, Yan J, Liu J, Li X. Immunomodulatory Factor TIM3 of Cytolytic Active Genes Affected the Survival and Prognosis of Lung Adenocarcinoma Patients by Multi-Omics Analysis. Biomedicines 2022 Sep 10; 10(9): 2248. doi: 10.3390\/biomedicines10092248. PMID: 36140350; PMCID: PMC9496572;","DOI":"10.3390\/biomedicines10092248"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Xiao J, Wu Y, Paranggan P, Gao W, Gao Z, Liu J, Wu L. Involvement of plasma lncRNA GSEC in sepsis discrimination and prognosis, and its correlation with macrophage inflammation and proliferation. Immunobiology 2022 Sep; 227(5): 152264. doi: 10.1016\/j.imbio.2022.152264. Epub 2022 Aug 28. PMID: 36049364;","DOI":"10.1016\/j.imbio.2022.152264"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Fu L, Long W, Liu T, Chen Y, Wu S, Li D, Liu K, Gao Y, Luo X. Decreased circulating levels of free triiodothyronine in Sepsis children and correlation analysis. BMC Pediatr 2022 Nov 29; 22(1): 687. doi: 10.1186\/s12887-022-03756-7. PMID: 36447149; PMCID: PMC9707259;","DOI":"10.1186\/s12887-022-03756-7"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Wu L, Liu Q, Ruan X, Luan X, Zhong Y, Liu J, Yan J, Li X. Multiple Omics Analysis of the Role of RBM10 Gene Instability in Immune Regulation and Drug Sensitivity in Patients with Lung Adenocarcinoma (LUAD). Biomedicines 2023 Jun 29; 11(7): 1861. doi: 10.3390\/biomedicines11071861. PMID: 37509501; PMCID: PMC10377220;","DOI":"10.3390\/biomedicines11071861"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Zhang C, Huang Q, He F. Correlation of small nucleolar RNA host gene 16 with acute respiratory distress syndrome occurrence and prognosis in sepsis patients. J Clin Lab Anal 2022 Jul; 36(7): e24516. doi: 10.1002\/jcla.24516. Epub 2022 May 27. PMID: 35622463; PMCID: PMC9280012;","DOI":"10.1002\/jcla.24516"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Wu L, Zheng Y, Ruan X, Wu D, Xu P, Liu J, Wu D, Li X. Long-chain noncoding ribonucleic acids affect the survival and prognosis of patients with esophageal adenocarcinoma through the autophagy pathway: construction of a prognostic model. Anticancer Drugs 2022 Jan 1; 33(1): e590-e603. doi: 10.1097\/CAD.0000000000001189. PMID: 343384240; PMCID: PMC8670349;","DOI":"10.1097\/CAD.0000000000001189"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Fang X, Fu W, Xu L, Qiu Y. Analysis of the diagnostic value of coagulation markers and coagulation function indices on the occurrence of DIC in sepsis and its prognosis. Allergol Immunopathol (Madr) 2024 Sep 1; 52(5): 65-72. doi: 10.15586\/aei.v52i5.1119. PMID: 39278853;","DOI":"10.15586\/ei.v52i5.1119"},{"key":"#cr-split#-ref24.1","doi-asserted-by":"crossref","unstructured":"Li L, Zhang S, Liu J, Luo Y. Abnormal Expression of SNHG7 Is a Biomarker for the Diagnosis and Prognosis of Neonatal Sepsis. Tohoku J Exp Med 2022 Nov 11","DOI":"10.1620\/tjem.2022.J066"},{"key":"#cr-split#-ref24.2","doi-asserted-by":"crossref","unstructured":"258(4): 257-63. doi: 10.1620\/tjem.2022.J066. Epub 2022 Aug 11. PMID: 35965096;","DOI":"10.1620\/tjem.2022.J066"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Wu L, Li H, Liu Y, Fan Z, Xu J, Li N, Qian X, Lin Z, Li X, Yan J. Research progress of 3D-bioprinted functional pancreas and in vitro tumor models. International Journal of Bioprinting 2024; 10(1): 1256. doi: 10.36922\/ijb.1256;","DOI":"10.36922\/ijb.1256"},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"Liufu R, Chen Y, Wan X X, Liu RT, Jiang W, Wang C, Peng JM, Weng L, Du B. Sepsis-induced Coagulopathy: The Different Prognosis in Severe Pneumonia and Bacteremia Infection Patients. Clin Appl Thromb Hemost 2023 Jan-Dec; 29: 10760296231219249. doi: 10.1177\/10760296231219249. PMID: 38126337; PMCID: PMC10748526;","DOI":"10.1177\/10760296231219249"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"Wu L, Zhong Y, Yu X, Wu D, Xu P, Lv L, Ruan X, Liu Q, Feng Y, Liu J, Li X. Selective polyadenylation predicts the efficacy of immunotherapy in patients with lung adenocarcinoma by multiple omics research. Anticancer Drugs 2022 Oct 1; 33(9): 943-59. doi: 10.1097\/CAD.0000000000001319. Epub 2022 Aug 9. PMID: 35946526; PMCID: PMC9481295;","DOI":"10.1097\/CAD.0000000000001319"},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"Wu H, Tang T, Deng H, Chen D, Zhang C, Luo J, Chen S, Zhang P, Yang J, Dong L, Chang T, Tang ZH. Immune checkpoint molecule Tim-3 promotes NKT apoptosis and predicts poorer prognosis in Sepsis. Clin Immunol 2023 Sep; 254: 109249. doi: 10.1016\/j.clim.2023.109249. Epub 2023 Feb 1. PMID: 36736642;","DOI":"10.1016\/j.clim.2023.109249"},{"key":"ref29","doi-asserted-by":"crossref","unstructured":"Wang C, Xu H, Gao R, Leng F, Huo F, Li Y, Liu S, Xu M, Bai J. CD19+CD24hiCD38hi regulatory B cells deficiency revealed severity and poor prognosis in patients with sepsis. BMC Immunol 2022 Nov 10; 23(1): 54. doi: 10.1186\/s12865-022-00528-x. PMID: 36357845; PMCID: PMC9648441;","DOI":"10.1186\/s12865-022-00528-x"},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Wu L, Li X, Qian X, Wang S, Liu J, Yan J. Lipid Nanoparticle (LNP) Delivery Carrier-Assisted Targeted Controlled Release mRNA Vaccines in Tumor Immunity. Vaccines (Basel) 2024 Feb 12; 12(2): 186. doi: 10.3390\/vaccines12020186. PMID: 38400169; PMCID: PMC10891594;","DOI":"10.3390\/vaccines12020186"},{"key":"ref31","doi-asserted-by":"crossref","unstructured":"Chen G, Zhou T, Xu J, Hu Q, Jiang J, Xu W. The Nonlinear Relationship Between Temperature and Prognosis in Sepsis-induced Coagulopathy Patients: A Retrospective Cohort Study from MIMIC-IV Database. West J Emerg Med 2024 Sep; 25(5): 697-707. doi: 10.5811\/westjem.18589. PMID: 39319800; PMCID: PMC11418858;","DOI":"10.5811\/WESTJEM.18589"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"Yu H, Yang Q, Qian Y, Luo S, Kong T, Yang G, Chen W, Xie F, Chen J, Xiong X, Wen D, Zhang Z. A positive correlation between serum lactate dehydrogenase level and in-hospital mortality in ICU sepsis patients: evidence from two large databases. Eur J Med Res 2024 Nov 1; 29(1): 525. doi: 10.1186\/s40001-024-02071-4. PMID: 39487549; PMCID: PMC11531135;","DOI":"10.1186\/s40001-024-02071-4"},{"key":"ref33","doi-asserted-by":"crossref","unstructured":"Jin P, Meng X, Yu C, Zhou C. Characteristics and prognosis of patients with pathogenic microorganism-positive sepsis AKI from ICU: a retrospective cohort study. Front Cell Infect Microbiol 2025 May 15; 15: 1509180. doi: 10.3389\/fcimb.2025.1509180. PMID: 40444157; PMCID: PMC12119599;","DOI":"10.3389\/fcimb.2025.1509180"},{"key":"ref34","doi-asserted-by":"crossref","unstructured":"Li Z, Wang L, Yang S, Luo B, Liu Y, Chen M, Wang C. Immune-associated molecular classification and prognosis signature of sepsis. PLoS One 2025 Jun 12; 20(6): e0326083. doi: 10.1371\/journal.pone.0326083. PMID: 40504881; PMCID: PMC12161593;","DOI":"10.1371\/journal.pone.0326083"},{"key":"ref35","doi-asserted-by":"crossref","unstructured":"Wu L, Chen X, Zeng Q, Lai Z, Fan Z, Ruan X, Li X, Yan J. NR5A2 gene affects the overall survival of LUAD patients by regulating the activity of CSCs through SNP pathway by OCLR algorithm and immune score. Heliyon 2024 Mar 28; 10(7): e28282. doi: 10.1016\/j.heliyon.2024.e28282. PMID: 38601554; PMCID: PMC11004709;","DOI":"10.1016\/j.heliyon.2024.e28282"},{"key":"ref36","doi-asserted-by":"crossref","unstructured":"Li Q, Qu L, Miao Y, Li Q, Zhang J, Zhao Y, Cheng R. A gene network database for the identification of key genes for diagnosis, prognosis, and treatment in sepsis. Sci Rep 2023 Dec 9; 13(1): 21815. doi: 10.1038\/s41598-023-49311-x. PMID: 38071387; PMCID: PMC10710458;","DOI":"10.1038\/s41598-023-49311-x"},{"key":"ref37","doi-asserted-by":"crossref","unstructured":"Fan Y, Y Z, Tang Y. Serum HMGB1 and soluble urokinase plasminogen activator receptor levels aid diagnosis and prognosis prediction of sepsis with acute respiratory distress syndrome. Biomark Med 2023 Feb; 17(4): 231-9. doi: 10.2217\/bmm-2022-0899. Epub 2023 May 9. PMID: 37158106;","DOI":"10.2217\/bmm-2022-0899"},{"key":"ref38","doi-asserted-by":"crossref","unstructured":"Wu L, Yang L, Qian X, Hu W, Wang S, Yan J. Mannan-Decorated Lipid Calcium Phosphate Nanoparticle Vaccine Increased the Antitumor Immune Response by Modulating the Tumor Microenvironment. J Funct Biomater 2024 Aug 16; 15(8): 229. doi: 10.3390\/jfb15080229. PMID: 39194667; PMCID: PMC11355305;","DOI":"10.3390\/jfb15080229"},{"key":"ref39","doi-asserted-by":"crossref","unstructured":"Ye Y, Chen Q, Wu D, Yu G, Liu J, Li Y, Xu Z, Lin L. Immune Dysregulation and Prognosis in Sepsis: Insights From a Posttranslational Perspective. Hum Mutat 2025 Jul 8; 2025: 5503939. doi: 10.1155\/humu\/5503939. PMID: 40666706; PMCID: PMC12263264;","DOI":"10.1155\/humu\/5503939"}],"container-title":["Journal of Medical Biochemistry"],"original-title":["Korelaciona analiza serumskog intestinalnog proteina za vezivanje masnih kiselina, D-laktatne kiseline i me\u0111u\u0107elijskog faktora adhezije-1 kod pacijenata sa sepsom i intestinalnom ishemijom"],"language":"en","link":[{"URL":"https:\/\/aseestant.ceon.rs\/index.php\/jomb\/article\/download\/61181\/29009","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/scindeks-clanci.ceon.rs\/data\/pdf\/1452-8258\/2026\/1452-82582604757S.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T14:19:20Z","timestamp":1776262760000},"score":1,"resource":{"primary":{"URL":"https:\/\/scindeks.ceon.rs\/Article.aspx?artid=1452-82582604757S"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.5937\/jomb0-61181","relation":{},"ISSN":["1452-8258","1452-8266"],"issn-type":[{"value":"1452-8258","type":"print"},{"value":"1452-8266","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}