{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T01:09:34Z","timestamp":1789261774584,"version":"build-2803163510"},"reference-count":14,"publisher":"The Korean Society of Gastrointestinal Endoscopy","issue":"2","license":[{"start":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T00:00:00Z","timestamp":1641168000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["e-ce.org"],"crossmark-restriction":true},"short-container-title":["Clin Endosc"],"published-print":{"date-parts":[[2022,3,31]]},"abstract":"<jats:p>Background\/Aims: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a standard procedure for obtaining tissue from lesions near the gastrointestinal lumen. However, there is a scarcity of information on the diagnostic performance of EUS-FNA for abdominal lymphadenopathy of unknown causes. To assess the accuracy of EUS-FNA in diagnosing abdominal lymphadenopathy of unknown etiology.Methods: The EUS records of patients with undiagnosed abdominal lymphadenopathy between 2010 and 2015 were reviewed.Results: A total of 42 patients were included in this study. Adequate specimens were obtained from 40 patients (95%). The final diagnoses were metastatic cancer (n=16), lymphoma (n=9), tuberculosis (n=8), inflammatory changes (n=6), and amyloidosis (n=1). For diagnosing malignancy, EUS-FNA had a sensitivity of 84.6%, specificity of 95.7%, positive predictive value of 91.7%, negative predictive value of 91.7%, and area under the receiver operating characteristic curve (AUROC) of 0.901. For the diagnosis of lymphoma, EUS-FNA was 100% accurate when combined with cytologic evaluation and immunohistochemical staining. The diagnostic sensitivity decreased to 75%, whereas the specificity remained 100%, for tuberculosis. The overall AUROC was 0.850. No procedure-related complications occurred.Conclusions: EUS-FNA showed high diagnostic performance for abdominal lymphadenopathy of unknown causes, especially malignancy, lymphoma, and tuberculosis. Therefore, it is a crucial diagnostic tool for this patient population.<\/jats:p>","DOI":"10.5946\/ce.2021.218-iden","type":"journal-article","created":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T05:29:54Z","timestamp":1641187794000},"page":"279-286","update-policy":"https:\/\/doi.org\/10.5946\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Role of Endoscopic Ultrasound-Guided Fine-Needle Aspiration in the Evaluation of Abdominal Lymphadenopathy of Unknown Etiology"],"prefix":"10.5946","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3737-8555","authenticated-orcid":true,"given":"Nonthalee","family":"Pausawasdi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3159-103X","authenticated-orcid":true,"given":"Kotchakon","family":"Maipang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7046-0529","authenticated-orcid":true,"given":"Tassanee","family":"Sriprayoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8334-0267","authenticated-orcid":true,"given":"Phunchai","family":"Charatcharoenwitthaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3961","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4161\/jig.23742"},{"key":"ref2","first-page":"1509","volume-title":"Current concepts in lymph node imaging","author":"Torabi","year":"2004"},{"key":"ref3","first-page":"1175","volume-title":"Differentiating between abdominal tuberculous lymphadenopathy and lymphoma using multidetector computed tomography (MDCT)","author":"Pongpornsup","year":"2013"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2011.06800.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4103\/2303-9027.117691"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2014.07.066"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(97)70164-1"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-009-0048-4"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.22013"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-944665"},{"key":"ref11","volume-title":"Global tuberculosis control : surveillance, planning, financing : WHO report 2007. [Internet]","year":"c2007"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.04064.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2018.8253"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2019.1704052"}],"container-title":["Clinical Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-ce.org\/upload\/pdf\/ce-2021-218-IDEN.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-ce.org\/journal\/view.php?doi=10.5946\/ce.2021.218-IDEN","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-ce.org\/upload\/pdf\/ce-2021-218-IDEN.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,7]],"date-time":"2022-04-07T23:58:11Z","timestamp":1649375891000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-ce.org\/journal\/view.php?doi=10.5946\/ce.2021.218-IDEN"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,31]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,3]]}},"URL":"https:\/\/doi.org\/10.5946\/ce.2021.218-iden","relation":{},"ISSN":["2234-2400","2234-2443"],"issn-type":[{"value":"2234-2400","type":"print"},{"value":"2234-2443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,31]]},"assertion":[{"value":"2021-08-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-03","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-31","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}