{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T22:46:36Z","timestamp":1789080396940,"version":"build-2803163510"},"reference-count":37,"publisher":"The Korean Society of Gastrointestinal Endoscopy","issue":"5","license":[{"start":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T00:00:00Z","timestamp":1682985600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["e-ce.org"],"crossmark-restriction":true},"short-container-title":["Clin Endosc"],"published-print":{"date-parts":[[2023,9,30]]},"abstract":"<jats:p>Background\/Aims: The safety of endoscopic retrograde cholangiopancreatography (ERCP) in hepatic cirrhosis and the impact of Child-Pugh class on post-ERCP complications need to be better studied. We investigated the post-ERCP complication rates in patients with cirrhosis compared with those without cirrhosis.Methods: We conducted a literature search of relevant databases to identify studies that reported post-ERCP complications in patients with hepatic cirrhosis.Results: Twenty-four studies comprising 28,201 patients were included. The pooled incidence of post-ERCP complications in cirrhosis was 15.5% (95% confidence interval [CI], 11.8%\u201319.2%; I2=96.2%), with an individual pooled incidence of pancreatitis 5.1% (95% CI, 3.1%\u20137.2%; I2=91.5%), bleeding 3.6% (95% CI, 2.8%\u20134.5%; I2=67.5%), cholangitis 2.9% (95% CI, 1.9%\u20133.8%; I2=83.4%), and perforation 0.3% (95% CI, 0.1%\u20130.5%; I2=3.7%). Patients with cirrhosis had a greater risk of post-ERCP complications (risk ratio [RR], 1.41; 95% CI, 1.16\u20131.71; I2=56.3%). The risk of individual odds of adverse events between cirrhosis and non-cirrhosis was as follows: pancreatitis (RR, 1.25; 95% CI, 1.06\u20131.48; I2=24.8%), bleeding (RR, 1.94; 95% CI, 1.59\u20132.37; I2=0%), cholangitis (RR, 1.15; 95% CI, 0.77\u20131.70; I2=12%), and perforation (RR, 1.20; 95% CI, 0.59\u20132.43; I2=0%).Conclusions: Cirrhosis is associated with an increased risk of post-ERCP pancreatitis, bleeding, and cholangitis.<\/jats:p>","DOI":"10.5946\/ce.2023.027","type":"journal-article","created":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T03:46:45Z","timestamp":1682999205000},"page":"578-589","update-policy":"https:\/\/doi.org\/10.5946\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Safety of endoscopic retrograde cholangiopancreatography (ERCP) in cirrhosis compared to non-cirrhosis and effect of Child-Pugh score on post-ERCP complications: a systematic review and 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