{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:53:06Z","timestamp":1788871986714,"version":"build-2803163510"},"reference-count":19,"publisher":"The Korean Society of Gastrointestinal Endoscopy","issue":"3","license":[{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["e-ce.org"],"crossmark-restriction":true},"short-container-title":["Clin Endosc"],"published-print":{"date-parts":[[2026,5,30]]},"abstract":"<jats:p>Background\/Aims: Endoscopic cyanoacrylate glue injection (END-G) is the recommended therapy for gastric varices; however, endoscopic ultrasound-guided coil and glue embolization (EUS-C+G) is increasingly utilized. This study compared the efficacy and safety of END-G and EUS-C+G.Methods: We retrospectively analyzed patients with gastric varices who underwent variceal obliteration. Propensity score matching (1:1) was used to balance baseline variables. The primary outcome was variceal obliteration at 4 weeks, and the secondary outcomes included adverse events (AEs), bleeding, ascites, and mortality. Predictors of incomplete obliteration were assessed using END-G.Results: A total of 442 patients were included. In the matched cohort (n=71\/group), EUS-C+G achieved higher obliteration rates than those of END-G (95.8% vs. 64.8%, p&lt;0.001) with a low glue volume (median 1.5 mL vs. 2.5 mL, p&lt;0.001). AEs were more frequent with EUS-C+G (25.4% vs. 8.5%, p=0.007), although they were generally mild and managed conservatively. The rates of bleeding, ascites, and 4-week mortality were similar between groups. Subgroup analysis showed the superiority of EUS-C+G in patients with isolated fundal varices (93.1% vs. 50.0%) and in secondary prophylaxis (95.0% vs. 53.3%), although with high AEs. Portal vein thrombosis (odds ratio, 154.086) and a varix size \u226518 mm (odds ratio, 2.664) predicted incomplete obliteration with END-G.Conclusions: EUS-C+G provides superior short-term obliteration compared with END-G, although with increased but milder AEs. Careful patient selection and expertise are essential.<\/jats:p>","DOI":"10.5946\/ce.2025.344","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T08:48:18Z","timestamp":1773305298000},"page":"459-465","update-policy":"https:\/\/doi.org\/10.5946\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Endoscopic ultrasound-guided coil and glue embolization is superior to endoscopic cyanoacrylate glue injection for gastric varices: a propensity-matched analysis from India"],"prefix":"10.5946","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6135-7351","authenticated-orcid":true,"given":"Rajesh","family":"Puri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9626-5243","authenticated-orcid":true,"given":"Suprabhat","family":"Giri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1460-8204","authenticated-orcid":true,"given":"Zubin Dev","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1233-8207","authenticated-orcid":true,"given":"Bimal Kumar","family":"Sahu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3961","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.01.058"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/medicina55070335"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/s0973-6883(12)60088-7"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-024-01681-4"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1055\/s-0044-1800831"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.5114\/ceh.2023.126077"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-024-11196-3"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1055\/a-1939-4887"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.12.022"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.10.027"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2024.06.038"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1590\/s0004-2803.201900000-08"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1055\/a-2408-6905"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2024.10.005"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2019.0360"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.vgie.2023.12.006"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097\/eus.0000000000000038"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.4103\/eus-d-21-00260"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1055\/a-2549-1165"}],"container-title":["Clinical Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-ce.org\/upload\/pdf\/ce-2025-344.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-ce.org\/journal\/view.php?doi=10.5946\/ce.2025.344","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-ce.org\/upload\/pdf\/ce-2025-344.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T06:55:53Z","timestamp":1779951353000},"score":1,"resource":{"primary":{"URL":"http:\/\/e-ce.org\/journal\/view.php?doi=10.5946\/ce.2025.344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,30]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,5]]}},"URL":"https:\/\/doi.org\/10.5946\/ce.2025.344","relation":{},"ISSN":["2234-2400","2234-2443"],"issn-type":[{"value":"2234-2400","type":"print"},{"value":"2234-2443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,30]]},"assertion":[{"value":"2025-09-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-12","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-30","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}