{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T11:51:02Z","timestamp":1766058662316,"version":"3.48.0"},"reference-count":0,"publisher":"Jaypee Brothers Medical Publishing","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAPI"],"published-print":{"date-parts":[[2025,11,10]]},"abstract":"<jats:p>Hemophilia is a coagulation disorder caused by deficient or absent clotting factors. It is a chronic \ndisease that starts from birth and requires lifelong intravenous administration of antihemophilic \nfactors. Healthcare professionals (HCPs), patients living with hemophilia, and their caregivers \nhave reported concerns regarding the challenges associated with the intravenous route and \nthe deterioration in their quality of life (QoL) due to the frequently repeated infusions necessary \nto maintain the desired levels of clotting factors. Patients with hemophilia and their caregivers \nhave often voiced their need for easier methods of treatment administration, similar to the way \ninsulin is delivered subcutaneously using a pen. Subcutaneous injection using a pen device is a \nknown way to improve treatment compliance and adherence in patients with chronic diseases. \nThe recent introduction of pen devices for hemophilia treatment administration is expected to \nreduce the administration burden and improve QoL. The narrative review presents the advantages \nof pen devices and patient and caregiver attitudes toward these newly introduced pen devices \nin hemophilia.<\/jats:p>","DOI":"10.59556\/japi.73.1198","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T11:47:56Z","timestamp":1766058476000},"page":"64-68","source":"Crossref","is-referenced-by-count":0,"title":["Hemophilia: Reducing Treatment Burden with Pen Devices"],"prefix":"10.59556","volume":"73","author":[{"given":"Chandrakala","family":"Shanmukaiah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parul","family":"Bhatt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kundan","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vaishali","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sujata","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil","family":"Panjwani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikas","family":"Katewa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonal","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kona K","family":"Radhika","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varun","family":"Bafna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikram K","family":"Gente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dnyaneshwar","family":"Upase","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2914","published-online":{"date-parts":[[2025,11,10]]},"container-title":["Journal of the Association of Physicians of India"],"original-title":[],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T11:47:59Z","timestamp":1766058479000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.japi.org\/article\/japi-73-11-64"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"references-count":0,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2025,11,10]]},"published-print":{"date-parts":[[2025,11,10]]}},"URL":"https:\/\/doi.org\/10.59556\/japi.73.1198","relation":{},"ISSN":["0004-5772"],"issn-type":[{"value":"0004-5772","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,10]]}}}