{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T11:51:03Z","timestamp":1766058663548,"version":"3.48.0"},"reference-count":0,"publisher":"Jaypee Brothers Medical Publishing","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAPI"],"published-print":{"date-parts":[[2025,11,10]]},"abstract":"<jats:p>Nanodrug delivery systems are gradually becoming the current \u201ctalk of the town\u201d due to \ntheir efficiency in treating different diseases in a more advanced manner when compared \nto conventional drug-delivery systems. It is well known that drugs can be given through \nvarious routes of administration, such as the popular oral, subcutaneous, and intravenous \nroutes. It is quite surprising that formulating these same drugs as nanoparticles (NPs) and \nadministering them to the patient could produce better results. Different studies have shown \nthe effects of nanodrug delivery systems in targeting cancer cells, ameliorating pulmonary \narterial hypertension, and providing improved treatments for ophthalmic conditions such as \nglaucoma. In most studies, nanodrug delivery systems have been shown to exhibit targeted \naction at the desired site or organ, low toxicity, and fewer systemic side effects. These new \ninsights can provide an enhanced understanding of the benefits of NP formulations of drugs, as \nwell as open up new pathways for future creative techniques in addressing emerging medical \nconditions. Furthermore, these formulations generally consist of polymer- or liposome\nbased or coated NPs, as they are easily biodegradable, meaning they have a higher ability \nto disintegrate and, at the same time, are not harmful to living tissues, thereby displaying \ngreater compatibility. New connections can be established through the utilization of NPs \nin the treatment of emerging diseases worldwide. Data from these studies could provide a \nfoundation for groundbreaking and innovative strategies in coping with or fighting even the \nrecent COVID-19 pandemic.<\/jats:p>","DOI":"10.59556\/japi.73.1205","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T11:47:56Z","timestamp":1766058476000},"page":"80-82","source":"Crossref","is-referenced-by-count":0,"title":["A Review of the Efficacy of Nanodrug Delivery Systems: Is It  Worth the Hype?"],"prefix":"10.59556","volume":"73","author":[{"given":"Daisy P","family":"Pugazhenthi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramya","family":"A","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dheenadhayalan","family":"Murugavel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karthickeyan","family":"Krishnan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shanmugasundaram","family":"Palani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2914","published-online":{"date-parts":[[2025,11,10]]},"container-title":["Journal of the Association of Physicians of India"],"original-title":[],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T11:48:01Z","timestamp":1766058481000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.japi.org\/article\/japi-73-11-80"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"references-count":0,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2025,11,10]]},"published-print":{"date-parts":[[2025,11,10]]}},"URL":"https:\/\/doi.org\/10.59556\/japi.73.1205","relation":{},"ISSN":["0004-5772"],"issn-type":[{"value":"0004-5772","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,10]]}}}