{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T09:10:56Z","timestamp":1766049056333,"version":"3.48.0"},"reference-count":0,"publisher":"Jaypee Brothers Medical Publishing","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAPI"],"published-print":{"date-parts":[[2025,11,10]]},"abstract":"<jats:p>Multisystem inflammatory syndrome in adults (MIS-A) is a postacute hyperinflammatory condition \nassociated with prior SARS-CoV-2 infection. While predominantly reported in children (MIS-C), \nMIS-A is increasingly recognized in adults and is characterized by multiorgan dysfunction, elevated \ninflammatory markers, and evidence of recent COVID-19. Timely diagnosis remains challenging \ndue to clinical overlap with other infectious and inflammatory conditions.\nWe report a case of a 36-year-old previously healthy male from Bihar, India, who presented with \nsevere epigastric pain, progressive dyspnea, and systemic symptoms. Clinical examination revealed \ntachypnea, hypotension, pedal edema, ascites, and hemorrhagic rashes over the abdomen. \nLaboratory evaluation showed leukocytosis, thrombocytopenia, acute kidney injury, transaminitis, \ncoagulopathy, markedly elevated inflammatory markers, and cardiac biomarkers. Chest imaging \nrevealed bilateral subpleural opacities and mild pleural effusions, indicating pulmonary \ninvolvement. Despite a negative SARS-CoV-2 RT-PCR result, high antibody titers confirmed a recent \nCOVID-19 infection. Imaging of the abdomen confirmed acute interstitial edematous pancreatitis. \nExtensive evaluation excluded tropical, autoimmune, and other infectious etiologies.\nThe present case was managed with high-dose corticosteroids, vasopressors, mechanical \nventilation, anticoagulation, and supportive therapy. He showed gradual improvement and \nwas discharged after 6 weeks. MIS-A should be considered in patients with recent SARS-CoV-2 \nexposure presenting with systemic inflammation, including respiratory and extrapulmonary \norgan dysfunction. Early recognition and immunomodulatory therapy are essential for favorable \noutcomes.<\/jats:p>","DOI":"10.59556\/japi.73.1228","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T09:06:23Z","timestamp":1766048783000},"page":"52-53","source":"Crossref","is-referenced-by-count":0,"title":["Post-Coronavirus Disease-2019-associated Multisystem  Inflammatory Syndrome in Adults: A Case from India"],"prefix":"10.59556","volume":"73","author":[{"given":"Anju","family":"Dinkar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jitendra","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhavya","family":"J","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saroj","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2914","published-online":{"date-parts":[[2025,11,10]]},"container-title":["Journal of the Association of Physicians of India"],"original-title":[],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T09:06:26Z","timestamp":1766048786000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.japi.org\/article\/japi-73-11-s1-52"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"references-count":0,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2025,11,10]]},"published-print":{"date-parts":[[2025,11,10]]}},"URL":"https:\/\/doi.org\/10.59556\/japi.73.1228","relation":{},"ISSN":["0004-5772"],"issn-type":[{"value":"0004-5772","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,10]]}}}