{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T09:25:06Z","timestamp":1766395506223,"version":"3.48.0"},"reference-count":0,"publisher":"Jaypee Brothers Medical Publishing","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAPI"],"published-print":{"date-parts":[[2025,12,10]]},"abstract":"<jats:p>Background: Sarcopenia is a frequent and prognostically significant complication of liver cirrhosis. \nHand grip strength (HGS) has emerged as a simple, noninvasive tool for assessing muscle function, \nyet limited data exist on its utility in Indian cirrhotic populations.\nAim: To evaluate the association of HGS with established prognostic scores and biochemical \nparameters in Indian patients with cirrhosis.\nMaterials and methods: In this cross-sectional observational study, 100 adult cirrhotic patients \nwere assessed between August 2022 and December 2023. HGS was measured using a validated \nhand-held dynamometer. Correlations between HGS and clinical scores of severity of cirrhosis \n[Child\u2013Turcotte\u2013Pugh (CTP), Model for End-Stage Liver Disease (MELD)] and biochemical markers \nwere analyzed using appropriate statistical methods.\nResults: Mean patient age was 59.2 \u00b1 8.46 years; 85% were male. The most common etiologies \nwere alcohol (46%) and viral hepatitis (26%). HGS declined significantly with increasing liver disease \nseverity: CTP A (34.0 \u00b1 1.48 kg), B (21.63 \u00b1 1.07 kg), and C (13.5 \u00b1 2.87 kg) (p &lt; 0.0001). HGS was \ninversely correlated with MELD score (r = \u20130.820) and showed strong positive correlations with \nserum albumin (r = +0.872) and hemoglobin (r = +0.59). Age, international normalized ratio (INR), \nand bilirubin were negatively correlated with HGS.\nConclusion: HGS is strongly associated with liver disease severity and key biochemical indicators. \nAs a bedside, radiation-free tool, it offers a practical method for assessing sarcopenia in cirrhosis, \nespecially in resource-limited settings.<\/jats:p>","DOI":"10.59556\/japi.73.1263","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T09:22:21Z","timestamp":1766395341000},"page":"40-43","source":"Crossref","is-referenced-by-count":0,"title":["Hand Grip Strength as a Functional Marker of Sarcopenia in  Liver Cirrhosis: Evidence from an Indian Cohort"],"prefix":"10.59556","volume":"73","author":[{"given":"Shyam","family":"Sunder","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narayan Lal","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prabhat Narain","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2914","published-online":{"date-parts":[[2025,12,10]]},"container-title":["Journal of the Association of Physicians of India"],"original-title":[],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T09:22:22Z","timestamp":1766395342000},"score":1,"resource":{"primary":{"URL":"https:\/\/japi.org\/article\/japi-73-12-40"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,10]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,12,10]]},"published-print":{"date-parts":[[2025,12,10]]}},"URL":"https:\/\/doi.org\/10.59556\/japi.73.1263","relation":{},"ISSN":["0004-5772"],"issn-type":[{"value":"0004-5772","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,10]]}}}