{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:27:14Z","timestamp":1789626434296,"version":"build-2803163510"},"reference-count":0,"publisher":"Jaypee Brothers Medical Publishing","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAPI"],"published-print":{"date-parts":[[2025,12,10]]},"abstract":"<jats:p>Background and aim: Abdominal tuberculosis (ATB) poses significant diagnostic challenges due \nto its varied clinical manifestations and its ability to mimic other diseases. Histopathology is a \npromising diagnostic tool to diagnose ATB. This narrative review aims to synthesize evidence on \nthe evolving role of histopathology in diagnosing ATB, highlighting its integration with molecular \nand microbiological diagnostics, and discussing its limitations and emerging technologies.\nMethodology: A structured search of databases including PubMed, Scopus, Web of Science, \nand Google Scholar was performed, focusing on literature published from January 2002. The \nreview includes peer-reviewed original articles on the diagnosis of ATB using histopathology and \nintegrated diagnostic modalities.\nResults: Histopathology remains crucial for diagnosing ATB, especially in resource-limited \nsettings, due to its ability to visualize granulomatous inflammation and other cellular features. \nThe integration of histopathology with molecular diagnostics like GeneXpert Mycobacterium \ntuberculosis\/rifampicin (MTB\/RIF) and tuberculosis polymerase chain reaction (TB-PCR) has \nimproved diagnostic accuracy. However, limitations include diagnostic overlap with other \nconditions and the impact of prior treatment on tissue samples. Emerging technologies such \nas digital pathology and artificial intelligence (AI)-driven image analysis are poised to enhance \ndiagnostic precision. Conclusion: The review underscores the importance of a multimodal diagnostic approach, \ncombining histopathology with other techniques to improve sensitivity and specificity. As ATB \ncontinues to be a global health concern, advancements in histopathological techniques and \ninterdisciplinary collaboration are essential for timely and accurate diagnosis.<\/jats:p>","DOI":"10.59556\/japi.73.1282","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:07:01Z","timestamp":1766398021000},"page":"e25-e28","source":"Crossref","is-referenced-by-count":1,"title":["Histopathology as a Diagnosis Tool of Abdominal  Tuberculosis: A Narrative Review of Evidence"],"prefix":"10.59556","volume":"73","author":[{"given":"Ashwin","family":"Prabhughate","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pravin M","family":"Rathi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2914","published-online":{"date-parts":[[2025,12,10]]},"container-title":["Journal of the Association of Physicians of India"],"original-title":[],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:07:03Z","timestamp":1766398023000},"score":1,"resource":{"primary":{"URL":"https:\/\/japi.org\/article\/japi-73-12-e25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,10]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,12,10]]},"published-print":{"date-parts":[[2025,12,10]]}},"URL":"https:\/\/doi.org\/10.59556\/japi.73.1282","relation":{},"ISSN":["0004-5772"],"issn-type":[{"value":"0004-5772","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,10]]}}}