{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T10:16:14Z","timestamp":1788171374797,"version":"build-2803163510"},"reference-count":23,"publisher":"Jaypee Brothers Medical Publishing","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.59556\/japi.74.1605","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T11:13:43Z","timestamp":1784200423000},"page":"42-48","source":"Crossref","is-referenced-by-count":0,"title":["Association of Hemoglobin\u2013Albumin\u2013Lymphocyte\u2013Platelet Count (HALP) Score and Type 2 Diabetes Retinopathy"],"prefix":"10.59556","volume":"74","author":[{"given":"Vijay","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kadiri","family":"Gururaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratibha","family":"Modi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Balivada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Raj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2914","reference":[{"issue":"(2):","key":"key20260831092853_B1","doi-asserted-by":"crossref","first-page":"112\u2013","DOI":"10.7861\/clinmed.2021-0792","article-title":"Diabetic retinopathy for the non-ophthalmologist.","volume":"22","author":"Fung","year":"2022;","journal-title":"Clin Med"},{"key":"key20260831092853_B2","doi-asserted-by":"crossref","first-page":"1077669.","DOI":"10.3389\/fendo.2022.1077669","article-title":"Diabetic retinopathy: looking forward to 2030.","volume":"13:","author":"Tan","year":"2023;","journal-title":"Front Endocrinol"},{"issue":"(6):","key":"key20260831092853_B3","doi-asserted-by":"crossref","first-page":"1816.","DOI":"10.3390\/ijms19061816","article-title":"Diabetic retinopathy: pathophysiology and treatments.","volume":"19","author":"Wang","year":"2018;","journal-title":"Int J Mol Sci"},{"issue":"(7):","key":"key20260831092853_B4","doi-asserted-by":"crossref","first-page":"1255\u2013","DOI":"10.1038\/s41433-020-0776-5","article-title":"Do we have enough ophthalmologists to manage vision-threatening diabetic retinopathy? A global perspective.","volume":"34","author":"Teo","year":"2020;","journal-title":"Eye"},{"issue":"(4):","key":"key20260831092853_B5","doi-asserted-by":"crossref","first-page":"318\u2013","DOI":"10.1016\/j.sjopt.2018.05.002","article-title":"Role of oxidative stress, inflammation, hypoxia and angiogenesis in the development of diabetic retinopathy.","volume":"32","author":"Al-Kharashi","year":"2018;","journal-title":"Saudi J Ophthalmol"},{"key":"key20260831092853_B6","doi-asserted-by":"crossref","first-page":"610318.","DOI":"10.3389\/fneur.2020.610318","article-title":"The Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score is associated with poor outcome of acute ischemic stroke.","volume":"11:","author":"Tian","year":"2020;","journal-title":"Front Neurol"},{"key":"key20260831092853_B7","doi-asserted-by":"crossref","first-page":"3827\u2013","DOI":"10.2147\/DMSO.S437580","article-title":"Exploring the correlation between the Systemic Immune Inflammation Index (SII), Systemic Inflammatory Response Index (SIRI), and Type 2 diabetic retinopathy.","volume":"16:","author":"Wang","year":"2023;","journal-title":"Diabetes Metab Syndr Obes"},{"key":"key20260831092853_B8","doi-asserted-by":"crossref","first-page":"2712.","DOI":"10.3389\/fimmu.2018.02712","article-title":"Role of platelets in leukocyte recruitment and resolution of inflammation.","volume":"9:","author":"Rossaint","year":"2018;","journal-title":"Front Immunol"},{"key":"key20260831092853_B9","first-page":"678.","article-title":"Platelets in inflammation: regulation of leukocyte activities and vascular repair.","volume":"5:","author":"Gros","year":"2014;","journal-title":"Front Immunol"},{"issue":"(3):","key":"key20260831092853_B10","first-page":"449\u2013","article-title":"The role of platelets in inflammation.","volume":"114","author":"Thomas","year":"2015;","journal-title":"Thromb Haemost"},{"issue":"(4):","key":"key20260831092853_B11","doi-asserted-by":"crossref","first-page":"427\u2013","DOI":"10.1139\/cjpp-2019-0670","article-title":"The screening of albumin as a key serum component in preventing release of neutrophil extracellular traps by selectively inhibiting mitochondrial ROS generation.","volume":"99","author":"Zheng","year":"2021;","journal-title":"Can J Physiol Pharmacol"},{"issue":"(2):","key":"key20260831092853_B12","doi-asserted-by":"crossref","first-page":"181\u2013","DOI":"10.1002\/jpen.1451","article-title":"Hypoalbuminemia: pathogenesis and clinical significance.","volume":"43","author":"Soeters","year":"2019;","journal-title":"JPEN J Parenter Enteral Nutr"},{"issue":"(6):","key":"key20260831092853_B13","doi-asserted-by":"crossref","first-page":"e0270019.","DOI":"10.1371\/journal.pone.0270019","article-title":"The correlation between serum albumin and diabetic retinopathy among people with type 2 diabetes mellitus: NHANES 2011\u20132020.","volume":"17","author":"Wang","year":"2022;","journal-title":"PLoS One"},{"key":"key20260831092853_B14","first-page":"759.","article-title":"Association between diabetic retinopathy and hemoglobin level.","volume":"4:","author":"Bahar","year":"2013;","journal-title":"Casp J Intern Med"},{"issue":"(11):","key":"key20260831092853_B15","doi-asserted-by":"crossref","first-page":"1833\u2013","DOI":"10.1093\/ecco-jcc\/jjad098","article-title":"Gut microbiome-generated phenylacetylglutamine from dietary protein is associated with Crohn's disease and exacerbates colitis in a mouse model possibly via platelet activation.","volume":"17","author":"Feng","year":"2023;","journal-title":"J Crohns Colitis"},{"key":"key20260831092853_B16","doi-asserted-by":"crossref","first-page":"153.","DOI":"10.18632\/oncotarget.28367","article-title":"What is hemoglobin, albumin, lymphocyte, platelet (HALP) score? A comprehensive literature review of HALP's prognostic ability in different cancer types.","volume":"14:","author":"Farag","year":"2023;","journal-title":"Oncotarget"},{"key":"key20260831092853_B17","doi-asserted-by":"crossref","first-page":"821\u2013","DOI":"10.2147\/JHC.S411521","article-title":"Prognostic significance of Hemoglobin, Albumin, Lymphocyte and Platelet (HALP) score in hepatocellular carcinoma.","volume":"10:","author":"Zhou","year":"2023;","journal-title":"J Hepatocell Carcinoma"},{"issue":"(11):","key":"key20260831092853_B18","doi-asserted-by":"crossref","first-page":"2002.","DOI":"10.3390\/medicina59112002","article-title":"Association of the HALP score with dyslipidemia: a large, nationwide retrospective study.","volume":"59","author":"Alshuweishi","year":"2023;","journal-title":"Medicina (Kaunas)"},{"issue":"(6):","key":"key20260831092853_B19","first-page":"706.","article-title":"The efficiency of the HALP score and the modified HALP score in predicting mortality in patients with acute heart failure presenting to the emergency department.","volume":"32","author":"Kocaoglu","year":"2023;","journal-title":"J Coll Physicians Surg Pak"},{"issue":"(3):","key":"key20260831092853_B20","doi-asserted-by":"crossref","first-page":"373\u2013","DOI":"10.1007\/s10238-018-0495-4","article-title":"Reduced mitochondrial DNA content in lymphocytes is associated with insulin resistance and inflammation in patients with impaired fasting glucose.","volume":"18","author":"Abu Bakar","year":"2018;","journal-title":"Clin Exp Med"},{"issue":"(2):","key":"key20260831092853_B21","doi-asserted-by":"crossref","first-page":"213\u2013","DOI":"10.3760\/cma.j.issn.0366-6999.20131906","article-title":"Mitochondrial apoptosis of lymphocyte is induced in type 2 diabetes.","volume":"127","author":"Xu","year":"2014;","journal-title":"Chin Med J (Engl)"},{"issue":"(8):","key":"key20260831092853_B22","doi-asserted-by":"crossref","first-page":"1169\u2013","DOI":"10.1016\/j.ophtha.2020.12.019","article-title":"Severity of diabetic retinopathy and the risk of future cerebrovascular disease, cardiovascular disease, and all-cause mortality.","volume":"128","author":"Modjtahedi","year":"2021;","journal-title":"Ophthalmology"},{"issue":"(8):","key":"key20260831092853_B23","doi-asserted-by":"crossref","first-page":"1322\u2013","DOI":"10.1111\/jdi.13480","article-title":"Update in the epidemiology, risk factors, screening, and treatment of diabetic retinopathy.","volume":"12","author":"Lin","year":"2021;","journal-title":"J Diabetes Investig"}],"container-title":["Journal of The Association of Physicians of India"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T09:30:26Z","timestamp":1788168626000},"score":1,"resource":{"primary":{"URL":"https:\/\/japi.org\/article\/japi-74-7-42"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":23,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.59556\/japi.74.1605"],"URL":"https:\/\/doi.org\/10.59556\/japi.74.1605","relation":{},"ISSN":["0004-5772"],"issn-type":[{"value":"0004-5772","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]}}}