{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:43:25Z","timestamp":1790207005010,"version":"4.1.0"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2011,12,7]],"date-time":"2011-12-07T00:00:00Z","timestamp":1323216000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["DE161525"],"award-info":[{"award-number":["DE161525"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["EB02520"],"award-info":[{"award-number":["EB02520"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003194","name":"New York Stem Cell Foundation","doi-asserted-by":"publisher","award":["CU09-3055"],"award-info":[{"award-number":["CU09-3055"]}],"id":[{"id":"10.13039\/100003194","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Regeneration of normal shape, architecture, and function of craniofacial tissues following congenital abnormality, trauma, or surgical treatment presents special problems to tissue engineering. Because of the great variations in properties of these tissues, currently available treatment options fall short of adequate care. We propose that the engineering of personalized bone graft customized to the patient and the specific clinical condition would revolutionize the way we currently treat craniofacial defects and discuss some of the current and emerging treatment modalities.<\/jats:p>","DOI":"10.5966\/sctm.2011-0020","type":"journal-article","created":{"date-parts":[[2012,5,11]],"date-time":"2012-05-11T11:27:30Z","timestamp":1336735650000},"page":"64-69","source":"Crossref","is-referenced-by-count":82,"title":["Concise Review: Personalized Human Bone Grafts for Reconstructing Head and Face"],"prefix":"10.1093","volume":"1","author":[{"given":"Sarindr","family":"Bhumiratana","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering, Columbia University, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordana","family":"Vunjak-Novakovic","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Columbia University, New York, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,12,7]]},"reference":[{"key":"2021122216512224600_ref1","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/nature01656","article-title":"Cranial skeletal biology","volume":"423","author":"Helms","year":"2003","journal-title":"Nature"},{"key":"2021122216512224600_ref2","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/j.1601-6343.2005.00328.x","article-title":"Bone\u2014special problems of the craniofacial region","volume":"8","author":"Herring","year":"2005","journal-title":"Orthod Craniofac Res"},{"key":"2021122216512224600_ref3","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1097\/SCS.0b013e3181edc829","article-title":"Bilateral orbitozygomatic reconstruction with tissue-engineered bone","volume":"21","author":"Taylor","year":"2010","journal-title":"J Craniofac Surg"},{"key":"2021122216512224600_ref4","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1600-0501.2006.01295.x","article-title":"Bone formation after sinus augmentation with engineered bone","volume":"18","author":"Zizelmann","year":"2007","journal-title":"Clin Oral Implants Res"},{"key":"2021122216512224600_ref5"},{"key":"2021122216512224600_ref6","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/00003086-200002000-00003","article-title":"Bone graft materials. 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