{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:52:48Z","timestamp":1787032368635,"version":"build-2736575974"},"reference-count":11,"publisher":"Georg Thieme Verlag KG","issue":"06","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"vor","delay-in-days":3468,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Plast Surg"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:p>Progressive facial hemiatrophy, also known as Parry-Romberg syndrome, is a progressive and self-limited deformation of the subcutaneous tissue volume on one side of the face that creates craniofacial asymmetry. We present the case of a patient with a five-year history of progressive right facial hemiatrophy, who underwent facial volumetric restoration using cell-assisted lipotransfer (CAL), which consists of an autologous fat graft enriched with adipose-derived stem cells (ASCs) extracted from the same patient. ASCs have the capacity to differentiate into adipocytes. They also promote angiogenesis, release angiogenic growth factors, and some can survive as stem cells. The use of autologous fat as a filler in soft tissue atrophy has been satisfactory in patients with mild and moderate Parry-Romberg syndrome. Currently, CAL has showed promising results in the long term by decreasing the rate of fat reabsorption. The permanence and stability of the graft in all the injected areas has showed that autologous fat grafts enriched with stem cells could be a promising technique for the correction of defects caused by this syndrome.<\/jats:p>","DOI":"10.5999\/aps.2012.39.6.659","type":"journal-article","created":{"date-parts":[[2012,11,19]],"date-time":"2012-11-19T04:49:27Z","timestamp":1353300567000},"page":"659-662","source":"Crossref","is-referenced-by-count":61,"title":["Cell-Assisted Lipotransfer for the Treatment of Parry-Romberg Syndrome"],"prefix":"10.1055","volume":"39","author":[{"given":"Yanko","family":"Castro-Govea","sequence":"additional","affiliation":[{"name":"Plastic, Reconstructive and Aesthetic Surgery Service, \"Dr. Jos\u00e9 E. Gonz\u00e1lez\" University Hospital, Universidad Aut\u00f3noma de Nuevo Leon, Monterrey, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar","family":"De La Garza-Pineda","sequence":"additional","affiliation":[{"name":"Plastic, Reconstructive and Aesthetic Surgery Service, \"Dr. Jos\u00e9 E. Gonz\u00e1lez\" University Hospital, Universidad Aut\u00f3noma de Nuevo Leon, Monterrey, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Lara-Arias","sequence":"additional","affiliation":[{"name":"Bone and Tissue Bank, \"Dr. Jos\u00e9 E. Gonz\u00e1lez\" University Hospital, Universidad Aut\u00f3noma de Nuevo Leon, Monterrey, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hern\u00e1n","family":"Chac\u00f3n-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Plastic, Reconstructive and Aesthetic Surgery Service, \"Dr. Jos\u00e9 E. Gonz\u00e1lez\" University Hospital, Universidad Aut\u00f3noma de Nuevo Leon, Monterrey, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Mecott-Rivera","sequence":"additional","affiliation":[{"name":"Plastic, Reconstructive and Aesthetic Surgery Service, \"Dr. Jos\u00e9 E. Gonz\u00e1lez\" University Hospital, Universidad Aut\u00f3noma de Nuevo Leon, Monterrey, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abel","family":"Salazar-Lozano","sequence":"additional","affiliation":[{"name":"Plastic, Reconstructive and Aesthetic Surgery Service, \"Dr. Jos\u00e9 E. Gonz\u00e1lez\" University Hospital, Universidad Aut\u00f3noma de Nuevo Leon, Monterrey, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Everardo","family":"Valdes-Flores","sequence":"additional","affiliation":[{"name":"Plastic, Reconstructive and Aesthetic Surgery Service, \"Dr. Jos\u00e9 E. Gonz\u00e1lez\" University Hospital, Universidad Aut\u00f3noma de Nuevo Leon, Monterrey, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,5,1]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"97e","DOI":"10.1097\/01.prs.0000182402.58757.b9","article-title":"Parry-Romberg syndrome","volume":"116","author":"V Terenzi","year":"2005","journal-title":"Plast Reconstr Surg"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/1098-2752(2000)20:4<167::AID-MICR4>3.0.CO;2-D","article-title":"Restoration of facial contour in Romberg's disease and hemifacial microsomia: experience with 118 cases","volume":"20","author":"F Inigo","year":"2000","journal-title":"Microsurgery"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1007\/s00266-006-0215-4","article-title":"Classification and treatment of facial tissue atrophy in Parry-Romberg disease","volume":"31","author":"J Guerrerosantos","year":"2007","journal-title":"Aesthetic Plast Surg"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/BF01570678","article-title":"Surgical remodeling of the silhouette by aspiration lipolysis or selective lipectomy","volume":"9","author":"YG Illouz","year":"1985","journal-title":"Aesthetic Plast Surg"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1097\/00006534-198311000-00002","article-title":"Lipodissection in body sculpturing: the dry procedure","volume":"72","author":"PF Fournier","year":"1983","journal-title":"Plast Reconstr Surg"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0094-1298(20)31069-5","article-title":"Facial recontouring with lipostructure","volume":"24","author":"SR Coleman","year":"1997","journal-title":"Clin Plast Surg"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.1089\/ten.2006.12.3375","article-title":"Cell-assisted lipotransfer: supportive use of human adipose-derived cells for soft tissue augmentation with lipoinjection","volume":"12","author":"D Matsumoto","year":"2006","journal-title":"Tissue Eng"},{"key":"ref8","first-page":"1178","article-title":"Cell-assisted lipotransfer for facial lipoatrophy: efficacy of clinical use of adipose-derived stem cells","volume":"34","author":"K Yoshimura","year":"2008","journal-title":"Dermatol Surg"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1007\/s00266-007-9019-4","article-title":"Cell-assisted lipotransfer for cosmetic breast augmentation: supportive use of adipose-derived stem\/stromal cells","volume":"32","author":"K Yoshimura","year":"2008","journal-title":"Aesthetic Plast Surg"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"e424","DOI":"10.1016\/j.bjps.2008.04.045","article-title":"Autologous fat transplantation for the treatment of Parry-Romberg syndrome","volume":"62","author":"A Sterodimas","year":"2009","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1097\/SAP.0b013e31826239f0","article-title":"Clinical application of human adipose tissue-derived mesenchymal stem cells in progressive hemifacial atrophy (Parry-Romberg disease) with microfat grafting techniques using 3-dimensional computed tomography and 3-dimensional camera","volume":"69","author":"KS Koh","year":"2012","journal-title":"Ann Plast Surg"}],"container-title":["Archives of Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.5999\/aps.2012.39.6.659.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T18:49:27Z","timestamp":1651430967000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.5999\/aps.2012.39.6.659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":11,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2022,5,1]]},"published-print":{"date-parts":[[2012,11]]}},"URL":"https:\/\/doi.org\/10.5999\/aps.2012.39.6.659","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2234-6163","2234-6171"],"issn-type":[{"value":"2234-6163","type":"print"},{"value":"2234-6171","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11]]}}}