{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T07:12:23Z","timestamp":1791875543431,"version":"4.3.4"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T00:00:00Z","timestamp":1650412800000},"content-version":"vor","delay-in-days":1754,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2017,7,15]],"date-time":"2017-07-15T00:00:00Z","timestamp":1500076800000},"content-version":"tdm","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["www.e-aps.org"],"crossmark-restriction":true},"short-container-title":["Arch Plast Surg"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:p>\n          Background  Lipedema is a condition consisting of painful bilateral increases in subcutaneous fat and interstitial fluid in the limbs with secondary lymphedema and fibrosis during later stages. Combined decongestive therapy (CDT) is the standard of care in most countries. Since the introduction of tumescent technique, liposuction has been used as a surgical treatment option. The aim of this study was to determine the outcome of liposuction used as treatment for lipedema.<\/jats:p><jats:p>\n          Methods  Twenty-five patients who received 72 liposuction procedures for the treatment of lipedema completed a standardized questionnaire. Lipedema-associated complaints and the need for CDT were assessed for the preoperative period and during 2 separate postoperative follow-ups using a visual analog scale and a composite CDT score. The mean follow-up times for the first postoperative follow-up and the second postoperative follow-up were 16 months and 37 months, respectively.<\/jats:p><jats:p>\n          Results  Patients showed significant reductions in spontaneous pain, sensitivity to pressure, feeling of tension, bruising, cosmetic impairment, and general impairment to quality of life from the preoperative period to the first postoperative follow-up, and these results remained consistent until the second postoperative follow-up. A comparison of the preoperative period to the last postoperative follow-up, after 4 patients without full preoperative CDT were excluded from the analysis, indicated that the need for CDT was reduced significantly. An analysis of the different stages of the disease also indicated that better and more sustainable results could be achieved if patients were treated in earlier stages.<\/jats:p><jats:p>\n          Conclusions  Liposuction is effective in the treatment of lipedema and leads to an improvement in quality of life and a decrease in the need for conservative therapy.<\/jats:p>","DOI":"10.5999\/aps.2017.44.4.324","type":"journal-article","created":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T23:53:33Z","timestamp":1500508413000},"page":"324-331","update-policy":"https:\/\/doi.org\/10.5999\/crossmark_policy","source":"Crossref","is-referenced-by-count":101,"title":["Liposuction in the Treatment of Lipedema: A Longitudinal Study"],"prefix":"10.1055","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1283-2982","authenticated-orcid":false,"given":"Mehran","family":"Dadras","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Klinikum Ernst von Bergmann, Potsdam, Germany"},{"name":"Department of Plastic Surgery, BG University Hospital Bergmannsheil, Ruhr-University Bochum, Bochum, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Joachim","family":"Mallinger","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Klinikum Klagenfurt am W\u00f6rthersee, Klagenfurt am W\u00f6rthersee, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cord Christian","family":"Corterier","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Klinikum Ernst von Bergmann, Potsdam, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sotiria","family":"Theodosiadi","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Klinikum Ernst von Bergmann, Potsdam, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mojtaba","family":"Ghods","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Klinikum Ernst von Bergmann, Potsdam, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,4,20]]},"reference":[{"key":"ref1","first-page":"184","article-title":"Lipedema of the legs: a syndrome characterized by fat legs and orthostatic edema","volume":"15","author":"EV Allen","year":"1940","journal-title":"Proc Staff Meet Mayo Clin"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.bjps.2003.12.020","article-title":"Painful fat syndrome in a male patient","volume":"57","author":"SG Chen","year":"2004","journal-title":"Br J Plast Surg"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1002\/ajmg.a.33313","article-title":"Lipedema: an inherited condition","volume":"152","author":"AH Child","year":"2010","journal-title":"Am J Med Genet A"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1055\/s-0037-1621466","article-title":"Lymphatic disturbances in lipoedema","volume":"32","author":"AJ van Geest","year":"2003","journal-title":"Phlebologie"},{"key":"ref5","first-page":"411","article-title":"MRI and ultrasonographic findings in the investigation of lymphedema and lipedema","volume":"82","author":"PB Dimakakos","year":"1997","journal-title":"Int Surg"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0009-9260(05)80927-4","article-title":"CT of swollen legs","volume":"41","author":"BF Vaughan","year":"1990","journal-title":"Clin Radiol"},{"key":"ref7","first-page":"1","article-title":"Lipedema","volume":"19","author":"U Herpertz","year":"1995","journal-title":"Z Lymphol"},{"key":"ref8","first-page":"303","article-title":"Microvascular disorders of adipose tissue","volume":"11","author":"SB Curri","year":"1986","journal-title":"J Mal Vasc"},{"key":"ref9","first-page":"170","article-title":"Microlymphatic aneurysms in patients with lipedema","volume":"34","author":"BR Amann-Vesti","year":"2001","journal-title":"Lymphology"},{"key":"ref10","first-page":"432","volume-title":"Isotopenlymphographische befunde beim lipodem","author":"KU Tiedjen","year":"1985"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.mvr.2009.01.005","article-title":"MR imaging of the lymphatic system in patients with lipedema and lipo-lymphedema","volume":"77","author":"C Lohrmann","year":"2009","journal-title":"Microvasc Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/0738-081X(95)00092-T","article-title":"Lymphatics and adipose tissue","volume":"13","author":"TJ Ryan","year":"1995","journal-title":"Clin Dermatol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1046\/j.1439-0353.2004.04051.x","article-title":"Lipoedema: current status, new perspectives","volume":"2","author":"I Meier-Vollrath","year":"2004","journal-title":"J Dtsch Dermatol Ges"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1097\/01.PRS.0000101506.84361.C9","article-title":"Tumescent and dry liposuction of lower extremities: differences in lymph vessel injury","volume":"113","author":"JN Hoffmann","year":"2004","journal-title":"Plast Reconstr Surg"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1097\/00006534-199411000-00014","article-title":"Lipedema: a clinical entity distinct from lymphedema","volume":"94","author":"GH Rudkin","year":"1994","journal-title":"Plast Reconstr Surg"},{"key":"ref16","first-page":"1S103","article-title":"Liposuction in lipoedema","volume":"129","author":"G Sattler","year":"2002","journal-title":"Ann Dermatol Venerol"},{"key":"ref17","first-page":"1S71","article-title":"Therapy of lipoedema syndrome by liposuction under tumescent local anaesthesia","volume":"129","author":"S Rapprich","year":"2002","journal-title":"Ann Dermatol Venerol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1177\/074880688700400403","article-title":"The tumescent technique for liposuction surgery","volume":"4","author":"JA Klein","year":"1987","journal-title":"Am J Cosmetic Surg"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s00266-008-9214-y","article-title":"Water jet-assisted liposuction for patients with lipoedema: histologic and immunohistologic analysis of the aspirates of 30 lipoedema patients","volume":"33","author":"JJ Stutz","year":"2009","journal-title":"Aesthetic Plast Surg"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1365-2133.2011.10566.x","article-title":"Tumescent liposuction in lipoedema yields good long-term results","volume":"166","author":"W Schmeller","year":"2012","journal-title":"Br J Dermatol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1610-0387.2010.07504.x","article-title":"Liposuction is an effective treatment for lipedema-results of a study with 25 patients","volume":"9","author":"S Rapprich","year":"2011","journal-title":"J Dtsch Dermatol Ges"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1111\/bjd.14289","article-title":"Long-term benefit of liposuction in patients with lipoedema: a follow-up study after an average of 4 and 8 years","volume":"174","author":"A Baumgartner","year":"2016","journal-title":"Br J Dermatol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1097\/01.PRS.0000111591.62685.F8","article-title":"Practice advisory on liposuction","volume":"113","author":"RE Iverson","year":"2004","journal-title":"Plast Reconstr Surg"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/00006534-200101000-00040","article-title":"General anesthesia in an office-based plastic surgical facility: a report on more than 23,000 consecutive office-based procedures under general anesthesia with no significant anesthetic complications","volume":"107","author":"SM Hoefflin","year":"2001","journal-title":"Plast Reconstr Surg"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1111\/j.1524-4725.2009.01284.x","article-title":"Safety of liposuction using exclusively tumescent local anesthesia in 3,240 consecutive cases","volume":"35","author":"L Habbema","year":"2009","journal-title":"Dermatol Surg"}],"container-title":["Archives of Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.e-aps.org\/upload\/pdf\/aps-2017-44-4-324.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.e-aps.org\/journal\/view.php?doi=10.5999\/aps.2017.44.4.324","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.5999\/aps.2017.44.4.324.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T22:43:40Z","timestamp":1650494620000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.5999\/aps.2017.44.4.324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":25,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2022,4,20]]},"published-print":{"date-parts":[[2017,7]]}},"URL":"https:\/\/doi.org\/10.5999\/aps.2017.44.4.324","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2234-6163","2234-6171"],"issn-type":[{"value":"2234-6163","type":"print"},{"value":"2234-6171","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"2017-01-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-15","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-15","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}