{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:40:35Z","timestamp":1791312035891,"version":"4.3.1"},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T00:00:00Z","timestamp":1648166400000},"content-version":"vor","delay-in-days":814,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T00:00:00Z","timestamp":1579046400000},"content-version":"tdm","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["e-aps.org"],"crossmark-restriction":true},"short-container-title":["Arch Plast Surg"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>\n          Background  Identifying patients who may be at high risk for wound complications postsarcoma resection and reconstruction is essential for improving functional outcomes and quality of life. Currently, the effect of timing on sarcoma reconstruction has been poorly investigated. The purpose of this study was to compare outcomes of delayed and immediate reconstruction in the setting of sarcoma resection requiring flap reconstruction in the lower extremity.<\/jats:p><jats:p>\n          Methods  A retrospective review of the senior author\u2019s sarcoma reconstruction patients from January 2005 to July 2017 was completed. All patients undergoing flap reconstruction of the lower extremity were included. Complications in the early postoperative period were compared between delayed and immediate reconstructive procedures.<\/jats:p><jats:p>\n          Results  A total of 32 patients (7 delayed, 25 immediate) were included in this study. There was a significantly increased rate of overall complications (100% vs. 28.0%, P=0.001) and rate of hematomas (28.6% vs. 0.0%, P=0.042) in the delayed reconstruction group. Other complications including dehiscence, seroma, infection, venous thrombosis, and total\/partial flap loss were also increased in the delayed reconstruction group, but this was not considered to be significant.<\/jats:p><jats:p>\n          Conclusions  This study suggests that delayed reconstruction following sarcoma resection of the lower extremity had a higher incidence of overall complications and hematoma formation. We emphasize the importance of early plastic and reconstructive surgeon referral and the necessity to closely monitor delayed reconstruction patients for complications.<\/jats:p>","DOI":"10.5999\/aps.2019.00780","type":"journal-article","created":{"date-parts":[[2020,1,20]],"date-time":"2020-01-20T00:54:42Z","timestamp":1579481682000},"page":"49-53","update-policy":"https:\/\/doi.org\/10.5999\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["A comparison of delayed versus immediate reconstruction following lower-extremity sarcoma resection"],"prefix":"10.1055","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9351-8487","authenticated-orcid":false,"given":"Sarah","family":"Zhou","sequence":"additional","affiliation":[{"name":"McGill University Faculty of Medicine, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3250-5305","authenticated-orcid":false,"given":"Alain J","family":"Azzi","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, McGill University Health Center, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0795-3109","authenticated-orcid":false,"given":"Tyler","family":"Safran","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, McGill University Health Center, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teanoosh","family":"Zadeh","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, McGill University Health Center, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,3,25]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1056\/NEJMra041866","article-title":"Soft-tissue sarcomas in 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