{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:25:31Z","timestamp":1782347131811,"version":"3.54.5"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2022,3,20]],"date-time":"2022-03-20T00:00:00Z","timestamp":1647734400000},"content-version":"vor","delay-in-days":443,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T00:00:00Z","timestamp":1610668800000},"content-version":"tdm","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["e-aps.org"],"crossmark-restriction":true},"short-container-title":["Arch Plast Surg"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>\n          Background  Reconstruction after removal of a malignant tumor in the head and neck region is crucial for restoring tissue integrity, function, and aesthetics. We retrospectively analyzed patients who underwent intraoral reconstruction surgery using radial forearm free flaps (RFFF) and anterolateral thigh free flaps (ALT) at a single institution to provide more information supporting the choice of a reconstruction method after removal of head and neck cancer.<\/jats:p><jats:p>\n          Methods  The charts of 708 patients who underwent head and neck reconstruction between 1998 and 2018 at the Department of Plastic and Reconstructive Surgery at our institution were retrospectively reviewed. Patients\u2019 age, sex, and history of radiation therapy, diabetes mellitus, and smoking were retrieved. The primary cancer site, types of defects, and complications were investigated.<\/jats:p><jats:p>\n          Results  Overall, 473 and 95 patients underwent reconstruction surgery with RFFF and ALT, respectively. RFFF was more often used in patients with cancers of the pharynx, larynx, esophagus, or tonsil, while ALT was more frequently used in patients with cancers of the mouth floor with tonsil or tongue involvement. The proportion of patients undergoing ALT increased gradually. Flap failure and donor site morbidities did not show significant differences between the two groups.<\/jats:p><jats:p>\n          Conclusions  RFFF and ALT flaps resulted in similar outcomes in terms of flap survival and donor site morbidity. ALT can be an option for head and neck reconstruction surgery in patients with large and complex defects or for young patients who want to hide their donor site scars.<\/jats:p>","DOI":"10.5999\/aps.2020.01529","type":"journal-article","created":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T02:27:00Z","timestamp":1611196020000},"page":"49-54","update-policy":"https:\/\/doi.org\/10.5999\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Anterolateral thigh free flaps and radial forearm free flaps in head and neck reconstruction: A 20-year analysis from a single institution"],"prefix":"10.1055","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8333-2868","authenticated-orcid":false,"given":"Simon","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7762-0940","authenticated-orcid":false,"given":"Jong Won","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1103-7047","authenticated-orcid":false,"given":"In Sik","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2625-5664","authenticated-orcid":false,"given":"Dae Hyun","family":"Lew","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8681-159X","authenticated-orcid":false,"given":"Tai Suk","family":"Roh","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3056-0503","authenticated-orcid":false,"given":"Won Jai","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2022,3,20]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.4143\/crt.2019.138","article-title":"Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2016","volume":"51","author":"KW Jung","year":"2019","journal-title":"Cancer Res Treat"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/S0140-6736(08)60728-X","article-title":"Head and neck cancer","volume":"371","author":"A Argiris","year":"2008","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1001\/archotol.1994.01880300047007","article-title":"Microvascular free flaps in head and neck reconstruction: report of 200 cases and review of complications","volume":"120","author":"ML Urken","year":"1994","journal-title":"Arch Otolaryngol Head Neck 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An experience with 672 anterolateral thigh flaps","volume":"109","author":"FC Wei","year":"2002","journal-title":"Plast Reconstr Surg"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/00006534-199309000-00005","article-title":"Free anterolateral thigh flaps for reconstruction of head and neck defects","volume":"92","author":"I Koshima","year":"1993","journal-title":"Plast Reconstr Surg"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1054\/bjps.1999.3250","article-title":"The versatile anterolateral thigh flap: a musculocutaneous flap in disguise in head and neck reconstruction","volume":"53","author":"F Demirkan","year":"2000","journal-title":"Br J Plast Surg"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/0007-1226(89)90142-2","article-title":"The anterolateral thigh flap; variations in its vascular pedicle","volume":"42","author":"I Koshima","year":"1989","journal-title":"Br J Plast Surg"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1097\/SCS.0b013e3181764ad6","article-title":"Anterolateral thigh flap for the reconstruction of head and neck defects: alternative or replacement of the radial forearm flap?","volume":"19","author":"V Valentini","year":"2008","journal-title":"J Craniofac Surg"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.3349\/ymj.2003.44.6.1078","article-title":"Standardization of flap design for oropharyngeal reconstruction after cancer ablation surgery","volume":"44","author":"DH Lew","year":"2003","journal-title":"Yonsei Med J"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1055\/s-0030-1255332","article-title":"Principles of head and neck reconstruction: an algorithm to guide flap selection","volume":"24","author":"H Chim","year":"2010","journal-title":"Semin Plast Surg"},{"key":"ref15","first-page":"297","article-title":"Comparative skin evaluation after split-thickness skin grafts using 2 different acellular dermal matrices to cover composite forearm defects","volume":"42","author":"MC Lee","year":"2017","journal-title":"J Hand Surg Am"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2164","DOI":"10.1016\/j.jhsa.2013.06.036","article-title":"Treatment of split-thickness skin graft-related forearm scar contractures with a carbon dioxide laser protocol: 3 case reports","volume":"38","author":"L Kroonen","year":"2013","journal-title":"J Hand Surg Am"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1097\/01.PRS.0000142476.36975.07","article-title":"Comparison of the radial forearm flap and the thinned anterolateral thigh cutaneous flap for reconstruction of tongue defects: an evaluation of donor-site morbidity","volume":"114","author":"CH Huang","year":"2004","journal-title":"Plast Reconstr Surg"},{"key":"ref18","first-page":"E945","article-title":"Short-term donor site morbidity: a comparison of the 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