{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T05:18:08Z","timestamp":1770268688410,"version":"3.49.0"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"06","license":[{"start":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T00:00:00Z","timestamp":1653177600000},"content-version":"vor","delay-in-days":202,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T00:00:00Z","timestamp":1636934400000},"content-version":"tdm","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002560","name":"Soonchunhyang University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002560","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["e-aps.org"],"crossmark-restriction":true},"short-container-title":["Arch Plast Surg"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p>A 3,480 g male neonate showed tachypnea symptom with a serum ionized calcium level of 0.66 mmol\/L by routine clinical analysis. He was injected calcium gluconate intravenously through femoral vein catheter to treat the hypocalcemia. On second day after the injection, he started to show erythema in the flank area. The lesion became firm and changed into whitish crust consist of small crystals. Abdominal X-ray and ultrasonography showed the accumulation of calcium deposit in the subcutaneous layer of the lesion. Surgical debridement was performed to remove the crust with calcium deposit and acellular fish skin graft rich in omega-3 (Kerecis) was applied to the defect site for secondary intention of the defect wound. After 2 months, the skin and soft tissue defect were fully covered with healthy normal skin without depression or contracture. This report is a first case of iatrogenic calcinosis cutis without extravasation symptom.<\/jats:p>","DOI":"10.5999\/aps.2020.01942","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T00:34:55Z","timestamp":1637282095000},"page":"641-645","update-policy":"https:\/\/doi.org\/10.5999\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["A rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconate"],"prefix":"10.1055","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3297-2336","authenticated-orcid":false,"given":"Kwang Hyeon","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Soonchunhyang University Bucheon Hospital, Bucheon, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2966-9122","authenticated-orcid":false,"given":"Eun Soo","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Soonchunhyang University Bucheon Hospital, Bucheon, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2022,5,22]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1007\/s12098-010-0176-0","article-title":"Hypocalcemia in the newborn","volume":"77","author":"A Jain","year":"2010","journal-title":"Indian J Pediatr"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/BF02723667","article-title":"Neonatal endocrinology","volume":"67","author":"J Oden","year":"2000","journal-title":"Indian J Pediatr"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1136\/bmj.39582.589433.BE","article-title":"Diagnosis and management of hypocalcaemia","volume":"336","author":"MS Cooper","year":"2008","journal-title":"BMJ"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/J.JHSB.2005.12.001","article-title":"Extravasation of calcium solution leading to calcinosis cutis surrounding the dorsal cutaneous branch of the ulnar nerve","volume":"31","author":"S Tuncer","year":"2006","journal-title":"J Hand Surg Br"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1001\/archderm.1988.01670060068019","article-title":"Calcinosis cutis following extravasation of calcium chloride","volume":"124","author":"D Goldminz","year":"1988","journal-title":"Arch Dermatol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"558","DOI":"10.2106\/00004623-198365040-00022","article-title":"Extravasation of injected calcium solution leading to calcifications in the upper extremity of the neonate: report of a case","volume":"65","author":"MS Wolfe","year":"1983","journal-title":"J Bone Joint Surg Am"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s00776-007-1217-z","article-title":"Neonate with calcinosis cutis following extravasation of calcium gluconate","volume":"13","author":"M Sonohata","year":"2008","journal-title":"J Orthop Sci"},{"key":"ref8","first-page":"215","article-title":"Calcium deposit following therapeutic injections in tetany of the newborn","volume":"53","author":"IH Tumpeer","year":"1936","journal-title":"Arch Pediatr"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/S0022-3476(36)80196-6","article-title":"Calcium deposition following the intramuscular administration of calcium gluconate: report of a case in a newborn infant","volume":"8","author":"FH Von Hofe","year":"1936","journal-title":"J Pediatr"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/s00247-004-1363-9","article-title":"Severe calcinosis cutis in an infant","volume":"35","author":"S Puvabanditsin","year":"2005","journal-title":"Pediatr Radiol"},{"key":"ref11","first-page":"277","article-title":"An infant with gigantic subcutaneous calcium deposition following extravasation of calcium gluconate","volume":"19","author":"H Caksen","year":"2002","journal-title":"Pediatr Dermatol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0190-9622(98)70001-5","article-title":"Cutaneous deposition diseases: part II","volume":"39(4 Pt 1)","author":"DM Touart","year":"1998","journal-title":"J Am Acad Dermatol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/0190-9622(95)91803-5","article-title":"Calcifying disorders of the skin","volume":"33(5 Pt 1)","author":"JS Walsh","year":"1995","journal-title":"J Am Acad Dermatol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1542\/peds.55.6.802","article-title":"Subcutaneous calcium deposition in the neonate associated with intravenous administration of calcium gluconate","volume":"55","author":"RS Ramamurthy","year":"1975","journal-title":"Pediatrics"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"856541","DOI":"10.1155\/2013\/856541","article-title":"Extravasation injuries in adults","volume":"2013","author":"S Al-Benna","year":"2013","journal-title":"ISRN Dermatol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1001\/archderm.1986.01660170076023","article-title":"Punch biopsy wounds treated with Monsel\u2019s solution or a collagen matrix: a comparison of healing","volume":"122","author":"RB Armstrong","year":"1986","journal-title":"Arch Dermatol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1177\/1534734615573661","article-title":"Healing rate and autoimmune safety of full-thickness wounds treated with fish skin acellular dermal matrix versus porcine small-intestine submucosa: a noninferiority study","volume":"14","author":"BT Baldursson","year":"2015","journal-title":"Int J Low Extrem Wounds"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/j.1524-475X.2008.00388.x","article-title":"Omega-3 fatty acids effect on wound healing","volume":"16","author":"JC McDaniel","year":"2008","journal-title":"Wound Repair Regen"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"93","DOI":"10.12687\/phleb2305-2-2016","article-title":"Marine omega3 wound matrix for the treatment of complicated wounds","volume":"45","author":"TT Trinh","year":"2016","journal-title":"Phlebologie"}],"container-title":["Archives of Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/e-aps.org\/upload\/pdf\/aps-2020-01942.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/e-aps.org\/journal\/view.php?doi=10.5999\/aps.2020.01942","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.5999\/aps.2020.01942.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T09:10:10Z","timestamp":1705569010000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.5999\/aps.2020.01942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":19,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2022,5,22]]},"published-print":{"date-parts":[[2021,11]]}},"URL":"https:\/\/doi.org\/10.5999\/aps.2020.01942","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2234-6163","2234-6171"],"issn-type":[{"value":"2234-6163","type":"print"},{"value":"2234-6171","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"2020-10-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-15","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-15","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}