{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T11:11:52Z","timestamp":1648725112224},"reference-count":0,"publisher":"Vilnius University Press","issue":"1","license":[{"start":{"date-parts":[[2016,4,7]],"date-time":"2016-04-07T00:00:00Z","timestamp":1459987200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AML"],"abstract":"<jats:p>Prosthetic valve thrombosis (PVT) is a\u00a0rare and fatal complication requiring immediate treatment. Optimal management of the\u00a0left-sided obstructive PVT is still controversial and depends on patient\u2019s status, estimated risk of surgery, thrombus location and size, and clinician\u2019s experience. We report a\u00a0 case of a\u00a0 71-year-old woman, presenting with signs of cardiogenic shock. Transesophageal echoscopy was used to diagnose acute obstructive thrombosis of the\u00a0 mechanical aortic valve. Concomitant coronary graft thrombosis was suspected due to signs of acute myocardial infarction. Thrombolysis with alteplase and subsequent stenting of the\u00a0 venous graft lead to successful resolution of the\u00a0thrombotic lesions and a\u00a0favourable patient outcome. Fibrinolytic therapy followed by angioplasty is a\u00a0rational treatment alternative for inoperable or high risk patients in the\u00a0case of concomitant mechanical valve and graft thrombosis.<\/jats:p>","DOI":"10.6001\/actamedica.v23i1.3263","type":"journal-article","created":{"date-parts":[[2016,4,8]],"date-time":"2016-04-08T06:37:07Z","timestamp":1460097427000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Successful application of thrombolysis and angioplasty in case of mechanical aortic valve and coronary graft thrombosis"],"prefix":"10.15388","volume":"23","author":[{"given":"Ieva","family":"Norkien\u0117","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ieva","family":"Ka\u017eukauskien\u0117","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robertas","family":"Samalavi\u010dius","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K\u0119stutis","family":"Ru\u010dinskas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6097","published-online":{"date-parts":[[2016,4,7]]},"container-title":["Acta medica Lituanica"],"original-title":[],"link":[{"URL":"https:\/\/www.journals.vu.lt\/AML\/article\/download\/21452\/20554","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.journals.vu.lt\/AML\/article\/download\/21452\/20554","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T06:21:18Z","timestamp":1610000478000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.journals.vu.lt\/AML\/article\/view\/21452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,7]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2016,4,7]]}},"URL":"https:\/\/doi.org\/10.6001\/actamedica.v23i1.3263","relation":{},"ISSN":["2029-4174","1392-0138"],"issn-type":[{"value":"2029-4174","type":"electronic"},{"value":"1392-0138","type":"print"}],"subject":[],"published":{"date-parts":[[2016,4,7]]}}}