{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T06:37:42Z","timestamp":1773383862418,"version":"3.50.1"},"reference-count":0,"publisher":"Vilnius University Press","issue":"2","license":[{"start":{"date-parts":[[2017,7,17]],"date-time":"2017-07-17T00:00:00Z","timestamp":1500249600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AML"],"abstract":"<jats:p>The objective. The\u00a0 aim is to present the\u00a0 major effects of cancer treatment (chemotherapy, radiotherapy, surgery) that the\u00a0 anaesthesiologist should consider preoperatively, and to review techniques of the\u00a0analgesic management of the\u00a0disease.\n Materials and Methods. To summarize the\u00a0 major challenges that cancer patients present for the\u00a0 anaesthesiologists, a\u00a0 literature\u00a0review\u00a0was conducted. Articles presenting evidence or reviewing the\u00a0 possible effects of anaesthetics on\u00a0 cancer\u00a0 cells were also included. Online databases of Science Direct, PubMed, and ELSEVIER, as well as reference lists of included studies were searched. Articles published from 2005 to 2016 were selected.\n Results. Anaesthesiologists should pay attention to patients receiving chemotherapy and its side effects on organ systems. Bleomycin causes pulmonary damage, anthracyclines are cardiotoxic, and platinum-based chemotherapy agents are nephrotoxic. A\u00a0lot of chemotherapy agents lead to abnormal liver function, vomiting, diarrhoea, etc. Surgery itself is suspected to be associated with an increased risk of metastasis and recurrence of cancer. Regional anaesthesia and general anaesthesia with propofol should be used and volatile agents should be avoided to prevent cancer patients from perioperative immunosuppression that leads to increased risk of cancer recurrence. Pain management for palliative patients remains a\u00a0major problem.\n Conclusions. To provide the\u00a0best treatment for cancer patients, cooperation of anaesthesiologists with oncologists and surgeons becomes imperative. It has been established that anaesthetic techniques and drugs could minimize the\u00a0perioperative inflammation. However, further research of the\u00a0perioperative \u201conco-anaesthetic\u201d is needed.<\/jats:p>","DOI":"10.6001\/actamedica.v24i2.3493","type":"journal-article","created":{"date-parts":[[2017,7,17]],"date-time":"2017-07-17T16:32:57Z","timestamp":1500309177000},"page":"121-127","source":"Crossref","is-referenced-by-count":15,"title":["Anaesthetic challenges in cancer patients: current therapies and pain management"],"prefix":"10.15388","volume":"24","author":[{"given":"J\u016brat\u0117","family":"Gudaityt\u0117","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominykas","family":"Dvylys","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Indr\u0117","family":"\u0160imeli\u016bnait\u0117","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"6097","published-online":{"date-parts":[[2017,7,17]]},"container-title":["Acta medica Lituanica"],"original-title":[],"link":[{"URL":"https:\/\/www.journals.vu.lt\/AML\/article\/download\/21332\/20444","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.journals.vu.lt\/AML\/article\/download\/21332\/20444","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T06:15:30Z","timestamp":1610000130000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.journals.vu.lt\/AML\/article\/view\/21332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,17]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,7,17]]}},"URL":"https:\/\/doi.org\/10.6001\/actamedica.v24i2.3493","relation":{},"ISSN":["2029-4174","1392-0138"],"issn-type":[{"value":"2029-4174","type":"electronic"},{"value":"1392-0138","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7,17]]}}}