{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T13:05:47Z","timestamp":1789045547518,"version":"build-2803163510"},"reference-count":23,"publisher":"Baskent University","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Clin Transplant"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.6002\/ect.2021.0425","type":"journal-issue","created":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T03:21:49Z","timestamp":1653362509000},"source":"Crossref","is-referenced-by-count":2,"title":[],"prefix":"10.6002","volume":"22","member":"4021","reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1. Teoh NC. Hepatic ischemia reperfusion injury: Contemporary perspectives on pathogenic mechanisms and basis for hepatoprotection-the good,bad and deadly. J Gastroenterol Hepatol. 2011;26 Suppl 1:180-187. doi:10.1111\/j.1440-1746.2010.06584.x","DOI":"10.1111\/j.1440-1746.2010.06584.x"},{"key":"ref1","unstructured":"2. Kim PK, Vallabhaneni R, Zuckerbraun BS, McCloskey C, Vodovotz Y, Biliar TR. Hypoxia renders hepatocytes susceptible to cell death by nitric oxide. Cell Mol Biol (Noisy-le-grand). 2005;51(3):329-335."},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3. Von Heesen M, Muller S, Keppler U, et al. Preconditioning by cilostazol protects against cold hepatic ischemia-reperfusion injury. Ann Transplant. 2015;20:160-168. doi:10.12659\/AOT.893031","DOI":"10.12659\/AOT.893031"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"4. Jaeschke H. Reperfusion injury after warm ischemia or cold storage of the liver: role of apoptotic cell death. Transplant Proc. 2002;34(7):2656-2658. doi:10.1016\/s0041-1345(02)03464-4","DOI":"10.1016\/S0041-1345(02)03464-4"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5. Ermis H, Parlakpinar H, Gulbas G, et al. Protective effect of dexpanthenol on bleomycin-induced pulmonary fibrosis in rats. Naunyn Schmiedebergs Arch Pharmacol. 2013;386(12):1103-1110. doi:10.1007\/s00210-013-0908-6","DOI":"10.1007\/s00210-013-0908-6"},{"key":"ref5","unstructured":"6. Li J, Li RJ, Lv GY, Liu HQ. The mechanisms and strategies to protect from hepatic ischemia-reperfusion injury. Eur Rev Med Pharmacol Sci. 2015;19(11):2036-2047."},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"7. McCuskey RS. Morphological mechanisms for regulating blood flow through hepatic sinusoids. Liver. 2000;20(1):3-7. doi:10.1034\/j.1600-0676.2000.020001003.x","DOI":"10.1034\/j.1600-0676.2000.020001003.x"},{"key":"ref7","unstructured":"8. Gressier B, Lebegue S, Brunet C, et al. Pro-oxidant properties of methotrexate: evaluation and prevention by anti-oxidant drug. Pharmazie. 1994;49:679-681."},{"key":"ref8","unstructured":"9. Berrigan MJ, Marinello AJ, Pavelic Z, Williams CJ, Struck RF, Gurtoo HL. Protective role of thiols in cyclophosphamide induced urotoxicity and depression of hepatic drug metabolism. Cancer Res. 1982;42(9):3688-3695."},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"10. Gressier B, Lebegue N, Brunet C, et al. Scavenging of reactive oxygen species by letosteine, a molecule with two blocked -SH groups. Comparison with free -SH drugs. Pharm World Sci. 1995;17(3):76-80. doi:10.1007\/BF01875435","DOI":"10.1007\/BF01875435"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"11. Kabasakal L, Sehirli AO, Cetinel S, Cikler E, Gedik N, Sener G. Mesna (2-mercaptoethane sulfonate) prevents ischemia\/reperfusion induced renal oxidative damage in rats. Life Sci. 2004;75(19):2329-2340. doi:10.1016\/j.lfs.2004.04.029","DOI":"10.1016\/j.lfs.2004.04.029"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"12. Sener G, Sehirli O, Ercan F, Sirvanci S, Gedik N, Kacmaz A. Protective effect of MESNA (2-mercaptoethane sulfonate) against hepatic ischemia\/reperfusion injury in rats. Surg Today. 2005;35(7):575-580. doi:10.1007\/s00595-004-2985-0","DOI":"10.1007\/s00595-004-2985-0"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"13. Ypsilantis P, Tentes I, Lambropoulou M, et al. Prophylaxis with mesna prevents oxidative stress induced by ischemia-reperfusion in the intestine via inhibition of nuclear factor-kappaB activation. J Gastroenterol Hepatol. 2008;23(2):328-335. doi:10.1111\/j.1440-1746.2007.05154.x","DOI":"10.1111\/j.1440-1746.2007.05154.x"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"14. Ypsilantis P, Lambropoulou M, Tentes I, Kortsaris A, Papadopoulos N, Simopoulos C. Mesna protects intestinal mucosa from ischemia\/reperfusion injury. J Surg Res. 2006;134(2):278-284. doi:10.1016\/j.jss.2005.12.031","DOI":"10.1016\/j.jss.2005.12.031"},{"key":"ref14","unstructured":"15. Gressier B, Cabanis A, Lebegue S, et al. Decrease of hypochlorous acid and hydroxyl radical generated by stimulated human neutrophils: comparison in vitro of some thiol-containing drugs. Methods Find Exp Clin Pharmacol. 1994;16(1):9-13."},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"16. Ypsilantis P, Tentes I, Anagnostopoulos K, Kontaris A, Simopoulus C. Mesna protects splanchnic organs from oxidative stress induced by pneumoperitoneum. Surg Endosc. 2009;23(3):583-589. doi:10.1007\/s00464-008-9887-y","DOI":"10.1007\/s00464-008-9887-y"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"17. Liu X, Xie W, Liu P, Duan M, Jia Z, Li W, Xu J. Mechanism of the cardioprotection of rhEPO pretreatment on suppressing the inflammatory response in ischemia-reperfusion. Life Sci. 2006;78(19):2255-2264. doi:10.1016\/j.lfs.2005.09.053","DOI":"10.1016\/j.lfs.2005.09.053"},{"key":"ref17","unstructured":"18. Liu X, Shen J, Jin Y, Duan M, Xu J. Recombinant human erythropoietin (rhEPO) preconditioning on nuclear factor-kappa B (NF -kB) activation & proinflammatory cytokines induced by myocardial ischaemia-reperfusion. Indian J Med Res. 2006;124(3):343-354."},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"19. Coleman TR, Westenfelder C, T\u00f6gel FE, et al. Cytoprotective doses of erythropoietin or carbamylated erythropoetin have markedly different procoagulant and vasoactive activities. Proc Natl Acad Sci USA. 2006;103(15):5965-5970. doi:10.1073\/pnas.0601377103","DOI":"10.1073\/pnas.0601377103"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"20. Hochhauser E, Pappo O, Ribakovsky E, et al. Recombinant human erythropoietin attenuates hepatic injury induced by ischemia\/reperfusion in an isolated mouse liver model. Apoptosis. 2008;13(1):77-86. doi:10.1007\/s10495-007-0155-8","DOI":"10.1007\/s10495-007-0155-8"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"21. Rieter RJ, Tan DX, Osuna C, Gitto E. Actions of melatonin in the reduction of oxidative stress. J Biomed Sci. 2000;7(6):444-458. doi:10.1007\/BF02253360","DOI":"10.1007\/BF02253360"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"22. Ypsilantis P, Lambropoulou M, Tentes I, et al. Impaired liver regeneration following partial hepatectomy using the pringle maneuvar: protective effect of mesna. J Gastroenterol Hepatol. 2009;24(4):623-632. doi:10.1111\/j.1440-1746.2008.05641.x","DOI":"10.1111\/j.1440-1746.2008.05641.x"},{"key":"ref22","unstructured":""}],"container-title":["Experimental and Clinical Transplantation"],"original-title":[],"deposited":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T04:34:38Z","timestamp":1719808478000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ectrx.org\/detail\/archive\/2024\/22\/5\/0\/358\/0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"URL":"https:\/\/doi.org\/10.6002\/ect.2021.0425","relation":{},"ISSN":["1304-0855","2146-8427"],"issn-type":[{"value":"1304-0855","type":"print"},{"value":"2146-8427","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5]]}}}