{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T08:56:41Z","timestamp":1776329801827,"version":"3.50.1"},"reference-count":28,"publisher":"Baskent University","issue":"Suppl 4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Clin Transplant"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.6002\/ect.donorsymp.2022.l6","type":"journal-article","created":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T02:30:08Z","timestamp":1661740208000},"page":"10-12","source":"Crossref","is-referenced-by-count":0,"title":["The Limited Value of the Extended Criteria Donor"],"prefix":"10.6002","volume":"20","author":[{"given":"Antoine","family":"Stephan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4021","reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Webb NJ, Johnson R, Postlethwaite RJ. Renal transplantation. Arch Dis Child. 2003;88(10):844-847. doi:10.1136\/adc.88.10.844","DOI":"10.1136\/adc.88.10.844"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"2. Wolfe RA, Ashby VB, Milford EL, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med. 1999;341(23):1725-1730. doi:10.1056\/NEJM199912023412303","DOI":"10.1056\/NEJM199912023412303"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3. Port FK, Bragg-Gresham JL, Metzger RA, et al. Donor characteristics associated with reduced graft survival: an approach to expanding the pool of kidney donors. Transplantation. 2002;74(9):1281-1286. doi:10.1097\/00007890-200211150-00014","DOI":"10.1097\/00007890-200211150-00014"},{"key":"ref3","unstructured":"4. Rule AD, Glassock RJ. The aging kidney. In: Curhan GC, Lam, AQ, eds. UpToDate UpToDate Inc; 2022. https:\/\/www.uptodate.com\/contents\/the-aging-kidney"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5. Hommos MS, Glassock RJ, Rule AD. Structural and functional changes in human kidneys with healthy aging. J Am Soc Nephrol. 2017;28(10):2838-2844. doi:10.1681\/ASN.2017040421","DOI":"10.1681\/ASN.2017040421"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"6. Schmitt R, Melk A. Molecular mechanisms of renal aging. Kidney Int. 2017;92(3):569-579. doi:10.1016\/j.kint.2017.02.036","DOI":"10.1016\/j.kint.2017.02.036"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"7. De Rosa P, Muscogiuri G, Sarno G. Expanded criteria donors in kidney transplantation: the role of older donors in a setting of older recipients. Int Scholarly Res Notices. 2013;2013:301025. doi:10.5402\/2013\/301025","DOI":"10.5402\/2013\/301025"},{"key":"ref7","unstructured":"8. Cole EH. Extended criteria kidney donors: benefits, risks, and optimal use. Canadian Council for Donation and Transplantation; April 2006. https:\/\/professionaleducation.blood.ca\/sites\/default\/files\/Extended_Criteria_Donors.pdf"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"9. Chao C-T, Tsai H-B, Lin Y-F, Ko W-J. Acute kidney injury in the elderly: only the tip of the iceberg. J Clin Gerontol Geriatr. 2014;5(1):7-12. doi:10.1016\/j.jcgg.2013.04.002","DOI":"10.1016\/j.jcgg.2013.04.002"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"10. Filiopoulos V, Boletis JN. Renal transplantation with expanded criteria donors: which is the optimal immunosuppression? World J Transplant. 2016;6(1):103-114. doi:10.5500\/wjt.v6.i1.103","DOI":"10.5500\/wjt.v6.i1.103"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"11. Mohan S, Chiles MC, Patzer RE, et al. Factors leading to the discard of deceased donor kidneys in the United States. Kidney Int. 2018;94(1):187-198. doi:10.1016\/j.kint.2018.02.016","DOI":"10.1016\/j.kint.2018.02.016"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"12. Hellemans R, Kramer A, De Meester J, et al. Does kidney transplantation with a standard or expanded criteria donor improve patient survival? Results from a Belgian cohort. Nephrol Dial Transplant. 2021;36(5):918-926. doi:10.1093\/ndt\/gfab024","DOI":"10.1093\/ndt\/gfab024"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"13. Fabrizii V, Kovarik J, Bodingbauer M, Kramar R, Horl WH, Winkelmayer WC. Long-term patient and graft survival in the Eurotransplant Senior Program: a single-center experience. Transplantation. 2005;80(5):582-589. doi:10.1097\/01.tp.0000168340.05714.99","DOI":"10.1097\/01.tp.0000168340.05714.99"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"14. Yang SS, Yang J, Ahn C, et al. The need for new donor stratification to predict graft survival in deceased donor kidney transplantation. Yonsei Med J. 2017;58(3):626-630. doi:10.3349\/ymj.2017.58.3.626","DOI":"10.3349\/ymj.2017.58.3.626"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"15. Hart A, Smith JM, Skeans MA, et al. OPTN\/SRTR 2017 Annual Data Report: kidney. Am J Transplant. 2019;19 Suppl 2:19-123. doi:10.1111\/ajt.15274","DOI":"10.1111\/ajt.15274"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"16. Gupta A, Francos G, Frank AM, Shah AP. KDPI score is a strong predictor of future graft function: Moderate KDPI (35 - 85) and high KDPI (> 85) grafts yield similar graft function and survival. Clin Nephrol. 2016;86(10):175-182. doi:10.5414\/CN108858","DOI":"10.5414\/CN108858"},{"key":"ref16","unstructured":"17. Organ Procurement and Transplantation Network. US Department of Health and Human Services. Kidney Donor Profile Index (KDPI) guide for clinicians. https:\/\/optn.transplant.hrsa.gov\/professionals\/by-topic\/guidance\/kidney-donor-profile-index-kdpi-guide-for-clinicians\/"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"18. Oniscu GC, Brown H, Forsythe JL. How great is the survival advantage of transplantation over dialysis in elderly patients? Nephrol Dial Transplant. 2004;19(4):945-951. doi:10.1093\/ndt\/gfh022","DOI":"10.1093\/ndt\/gfh022"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"19. Girerd S, Girerd N, Duarte K, et al. Preemptive second kidney transplantation is associated with better graft survival compared with non-preemptive second transplantation: a multicenter French 2000-2014 cohort study. Transpl Int. 2018;31(4):408-423. doi:10.1111\/tri.13105","DOI":"10.1111\/tri.13105"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"20. Ethics Committee of the Transplantation S. The consensus statement of the Amsterdam Forum on the Care of the Live Kidney Donor. Transplantation. 2004;78(4):491-492. doi:10.1097\/01.tp.0000136654.85459.1e","DOI":"10.1097\/01.TP.0000136654.85459.1E"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"21. Plage H, Pielka P, Liefeldt L, et al. Extended criteria donors in living kidney transplantation including donor age, smoking, hypertension and BMI. Ther Clin Risk Manag. 2020;16:787-793. doi:10.2147\/TCRM.S256962","DOI":"10.2147\/TCRM.S256962"},{"key":"ref21","unstructured":"22. International Registry in Organ Donation and Transplantation. Accessed December 2020. www.irodat.org"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"23. Raman M, Middleton RJ, Kalra PA, Green D. Estimating renal function in old people: an in-depth review. Int Urol Nephrol. 2017;49(11):1979-1988. doi:10.1007\/s11255-017-1682-z","DOI":"10.1007\/s11255-017-1682-z"},{"key":"ref23","unstructured":"24. Heiene R; International Renal Interest Society. Interpreting blood creatinine concentration in dogs (revised 2022). http:\/\/www.iris-kidney.com\/education\/creatinine_dogs.html"},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"25. Chawla LS, Ronco C. Renal stress testing in the assessment of kidney disease. Kidney Int Rep. 2016;1(1):57-63. doi:10.1016\/j.ekir.2016.04.005","DOI":"10.1016\/j.ekir.2016.04.005"},{"key":"ref25","doi-asserted-by":"publisher","unstructured":"26. Locke JE, Reed RD, Massie A, et al. Obesity increases the risk of end-stage renal disease among living kidney donors. Kidney Int. 2017;91(3):699-703. doi:10.1016\/j.kint.2016.10.014","DOI":"10.1016\/j.kint.2016.10.014"},{"key":"ref26","doi-asserted-by":"publisher","unstructured":"27. Barbari A, Stephan A, Masri M, et al. Consanguinity-associated kidney diseases in Lebanon: an epidemiological study. Mol Immunol. 2003;39(17-18):1109-1114. doi:10.1016\/s0161-5890(03)00065-8","DOI":"10.1016\/S0161-5890(03)00065-8"},{"key":"ref27","doi-asserted-by":"publisher","unstructured":"28. Ross LF. Living kidney donors and ESRD. Am J Kidney Dis. 2015;66(1):23-27. doi:10.1053\/j.ajkd.2015.01.032","DOI":"10.1053\/j.ajkd.2015.01.032"}],"container-title":["Experimental and Clinical Transplantation"],"original-title":[],"deposited":{"date-parts":[[2022,8,29]],"date-time":"2022-08-29T03:07:15Z","timestamp":1661742435000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.ectrx.org\/detail\/supplement\/2022\/20\/8\/4\/10\/0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":28,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2022,8]]}},"URL":"https:\/\/doi.org\/10.6002\/ect.donorsymp.2022.l6","relation":{},"ISSN":["1304-0855","2146-8427"],"issn-type":[{"value":"1304-0855","type":"print"},{"value":"2146-8427","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8]]}}}