{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T07:59:41Z","timestamp":1785311981658,"version":"3.55.0"},"reference-count":23,"publisher":"Baskent University","issue":"Supp 2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Exp Clin Transplant"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.6002\/ect.mesot2025.o89","type":"journal-issue","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T10:48:55Z","timestamp":1785235735000},"source":"Crossref","is-referenced-by-count":0,"title":[],"prefix":"10.6002","volume":"24","member":"4021","reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1. Gao Y, Long Q, Yang H, et al. Transcriptomics and metabolomics study in mouse kidney of the molecular mechanism underlying energy metabolism response to hypoxic stress in highland areas. Exp Ther Med. 2023;26(5):533. doi:10.3892\/etm.2023.12232","DOI":"10.3892\/etm.2023.12232"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"2. Foresto-Neto O, da Silva AR, Cipelli M, Santana-Novelli FP, Camara NOS. The impact of hypoxia-inducible factors in the pathogenesis of kidney diseases: a link through cell metabolism. Kidney Res Clin Pract. 2023;42(5):561-578. doi:10.23876\/j.krcp.23.012","DOI":"10.23876\/j.krcp.23.012"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3. Liu H, Li Y, Xiong J. The role of hypoxia-inducible factor-1 alpha in renal disease. Molecules. 2022;27(21):7318. doi:10.3390\/molecules27217318","DOI":"10.3390\/molecules27217318"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"4. Habas E Sr, Al Adab A, Arryes M, et al. Anemia and hypoxia impact on chronic kidney disease onset and progression: review and updates. Cureus. 2023;15(10):e46737. doi:10.7759\/cureus.46737","DOI":"10.7759\/cureus.46737"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5. Wang T, Guo W, Lv X, et al. Catalytically self-supplied oxygen to alleviate hypoxia for treatment of acute kidney injury. Adv Funct Mater. 2024;34(44):2404774. doi:10.1002\/adfm.202404774","DOI":"10.1002\/adfm.202404774"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"6. Xu Y, Kong X, Li J, et al. Mild hypoxia enhances the expression of HIF and VEGF and triggers the response to injury in rat kidneys. Front Physiol. 2021;12:690496. doi:10.3389\/fphys.2021.690496","DOI":"10.3389\/fphys.2021.690496"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"7. Chung C. From oxygen sensing to angiogenesis: targeting the hypoxia signaling pathway in metastatic kidney cancer. Am J Health Syst Pharm. 2020;77(24):2064-2073. doi:10.1093\/ajhp\/zxaa308","DOI":"10.1093\/ajhp\/zxaa308"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"8. Xu ZH, Wang C, He YX, et al. Hypoxia-inducible factor protects against acute kidney injury via the Wnt\/\u03b2-catenin signaling pathway. Am J Physiol Renal Physiol. 2022;322(6):F611-F624. doi:10.1152\/ajprenal.00023.2022","DOI":"10.1152\/ajprenal.00023.2022"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"9. Yuan Y, Li X, Chu Y, Ye G, Yang L, Dong Z. Long non-coding RNA H19 augments hypoxia\/reoxygenation-induced renal tubular epithelial cell apoptosis and injury by the miR-130a\/BCL2L11 pathway. Front Physiol. 2021;12:632398. doi:10.3389\/fphys.2021.632398","DOI":"10.3389\/fphys.2021.632398"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"10. Lu X, Tan Q, Ma J, Zhang J, Yu P. Emerging role of lncRNA regulation for NLRP3 inflammasome in diabetes complications. Front Cell Dev Biol. 2021;9:792401. doi:10.3389\/fcell.2021.792401","DOI":"10.3389\/fcell.2021.792401"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"11. Xie L, He J, Mao J, Zhang Q, Bo H, Li L. The interplay between H19 and HIF-1\u03b1 in mitochondrial dysfunction in myocardial infarction. Cell Signal. 2023;112:110919. doi:10.1016\/j.cellsig.2023.110919","DOI":"10.1016\/j.cellsig.2023.110919"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"12. He Y, Lang X, Cheng D, Zhang T, Yang Z, Xiong R. miR-30a-5p inhibits hypoxia\/reoxygenation-induced oxidative stress and apoptosis in HK-2 renal tubular epithelial cells by targeting glutamate dehydrogenase 1. Oncol Rep. 2020;44(4):1539-1549. doi:10.3892\/or.2020.7718","DOI":"10.3892\/or.2020.7718"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"13. Li Z, Gong C, Wei H. Long non-coding RNA H19 aggravates keloid progression by upregulating SMAD family member 5 expression via miR-196b-5p. Bioengineered. 2022;13(1):1447-1458. doi:10.1080\/21655979.2021.2019868","DOI":"10.1080\/21655979.2021.2019868"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"14. Strober W. Trypan blue exclusion test of cell viability. Curr Protoc Immunol. 2015;111:A3.B.1-A3.B.3. doi:10.1002\/0471142735.ima03bs111","DOI":"10.1002\/0471142735.ima03bs111"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"15. Bia\u0142kowska K, Komorowski P, Bryszewska M, Mi\u0142owska K. Spheroids as a type of three-dimensional cell cultures: examples of methods of preparation and the most important application. Int J Mol Sci. 2020;21(17):6225. doi:10.3390\/ijms21176225","DOI":"10.3390\/ijms21176225"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"16. Wang X, Zhao D, Xie H, Hu Y. Interplay of long non-coding RNAs and HIF-1\u03b1: a new dimension to understanding hypoxia-regulated tumor growth and metastasis. Cancer Lett. 2021;499:49-59. doi:10.1016\/j.canlet.2020.11.007","DOI":"10.1016\/j.canlet.2020.11.007"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"17. Zhong B, Sun S, Tan KS, et al. Hypoxia-inducible factor 1\u03b1 activates the NLRP3 inflammasome to regulate epithelial differentiation in chronic rhinosinusitis. J Allergy Clin Immunol. 2023;152(6):1444-1459. doi:10.1016\/j.jaci.2023.09.020","DOI":"10.1016\/j.jaci.2023.09.020"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"18. Liu Y, Luo Y, Zhang A, et al. Long non-coding RNA H19 promotes NLRP3-mediated pyroptosis after subarachnoid hemorrhage in rats. Transl Stroke Res. 2023;14(6):987-1001. doi:10.1007\/s12975-022-01104-6","DOI":"10.1007\/s12975-022-01104-6"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"19. Calderon-Jofre R, Bernal G, Moraga D, Moraga FA. Interleukins expression by rat lymphocytes exposed to chronic intermittent normobaric hypoxia. Front Physiol. 2025;16:1520174. doi:10.3389\/fphys.2025.1520174","DOI":"10.3389\/fphys.2025.1520174"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"20. Wang L, Xu B, Sun S, Wang B. Overexpression of long non-coding RNA H19 relieves hypoxia-induced injury by down-regulating microRNA-107 in neural stem cells. Neurosci Lett. 2021;753:135855. doi:10.1016\/j.neulet.2021.135855","DOI":"10.1016\/j.neulet.2021.135855"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"21. Takkar S, Sharma V, Ghosh S, Suri A, Sarkar C, Kulshreshtha R. Hypoxia-inducible miR-196a modulates glioblastoma cell proliferation and migration through complex regulation of NRAS. Cell Oncol (Dordr). 2021;44(2):433-451. doi:10.1007\/s13402-020-00580-y","DOI":"10.1007\/s13402-020-00580-y"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"22. Jiang W, Shi X, Sun L, et al. Exosomal miR-30a-5p promoted intrahepatic cholangiocarcinoma progression by increasing angiogenesis and vascular permeability in a PDCD10-dependent manner. Int J Biol Sci. 2023;19(14):4571-4587. doi:10.7150\/ijbs.83170","DOI":"10.7150\/ijbs.83170"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"23. Fang Y, Zou L, He W. miR-30a-5p mitigates autophagy by regulating the Beclin-1\/ATG16 pathway in renal ischemia\/reperfusion injury. Int J Mol Med. 2021;48(1):144. doi:10.3892\/ijmm.2021.4977","DOI":"10.3892\/ijmm.2021.4977"}],"container-title":["Experimental and Clinical Transplantation"],"original-title":[],"deposited":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T07:04:57Z","timestamp":1785308697000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ectrx.org\/detail\/supplement\/2026\/24\/6\/2\/218\/0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":23,"journal-issue":{"issue":"Supp 2","published-print":{"date-parts":[[2026,7]]}},"URL":"https:\/\/doi.org\/10.6002\/ect.mesot2025.o89","relation":{},"ISSN":["1304-0855","2146-8427"],"issn-type":[{"value":"1304-0855","type":"print"},{"value":"2146-8427","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]}}}