{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T09:12:17Z","timestamp":1790673137183,"version":"4.1.0"},"reference-count":0,"publisher":"Harborside Press, LLC","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JADPRO"],"published-print":{"date-parts":[[2022,7,1]]},"abstract":"<jats:p>Richter transformation is a devastating and rare but not uncommon development of an aggressive B-cell lymphoma in patients with chronic lymphocytic leukemia or small lymphocytic lymphoma. Prognosis is dismal, with survival generally in the realm of months to a couple of years. Many patients progress quickly after traditional first-line immunochemotherapy. Nonetheless, novel therapies are on the horizon. It is important that the advanced practitioner have awareness and knowledge of this condition in order to furnish a crucial timely diagnosis and to provide appropriate treatment.<\/jats:p>","DOI":"10.6004\/jadpro.2022.13.5.6","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T03:27:07Z","timestamp":1659583627000},"page":"525-534","source":"Crossref","is-referenced-by-count":10,"title":["Richter Transformation: Clinical Manifestations, Evaluation, and Management"],"prefix":"10.6004","volume":"13","author":[{"given":"Melanie","family":"Douglas, MS, PA-C","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4047","published-online":{"date-parts":[[2022,7,1]]},"container-title":["Journal of the Advanced Practitioner in Oncology"],"original-title":[],"deposited":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T03:27:16Z","timestamp":1659583636000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.advancedpractitioner.com\/issues\/volume-13,-number-5-(july-2022)\/richter-transformation-clinical-manifestations,-evaluation,-and-management.aspx"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,1]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,7,1]]},"published-print":{"date-parts":[[2022,7,1]]}},"URL":"https:\/\/doi.org\/10.6004\/jadpro.2022.13.5.6","relation":{},"ISSN":["2150-0878"],"issn-type":[{"value":"2150-0878","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7,1]]}}}