{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T19:31:51Z","timestamp":1793129511051,"version":"4.5.0"},"reference-count":258,"publisher":"Harborside Press, LLC","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:p>Soft tissue sarcomas (STS) are rare malignancies of mesenchymal cell origin that display a heterogenous mix of clinical and pathologic characteristics. STS can develop from fat, muscle, nerves, blood vessels, and other connective tissues. The evaluation and treatment of patients with STS requires a multidisciplinary team with demonstrated expertise in the management of these tumors. The complete NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Soft Tissue Sarcoma provide recommendations for the diagnosis, evaluation, and treatment of extremity\/superficial trunk\/head and neck STS, as well as retroperitoneal\/intra-abdominal STS, desmoid tumors, and rhabdomyosarcoma. This portion of the NCCN Guidelines discusses general principles for the diagnosis and treatment of retroperitoneal\/intra-abdominal STS, outlines treatment recommendations, and reviews the evidence to support the guidelines recommendations.<\/jats:p>","DOI":"10.6004\/jnccn.2022.0035","type":"journal-article","created":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T15:39:40Z","timestamp":1657726780000},"page":"815-833","source":"Crossref","is-referenced-by-count":408,"title":["Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology"],"prefix":"10.6004","volume":"20","author":[{"given":"Margaret","family":"von Mehren","sequence":"first","affiliation":[{"name":"1Fox Chase Cancer Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Kane","sequence":"additional","affiliation":[{"name":"2Roswell Park Comprehensive Cancer Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Agulnik","sequence":"additional","affiliation":[{"name":"3City of Hope National Medical Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilyn M.","family":"Bui","sequence":"additional","affiliation":[{"name":"4Moffitt Cancer Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janai","family":"Carr-Ascher","sequence":"additional","affiliation":[{"name":"5UC Davis Comprehensive Cancer Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"Choy","sequence":"additional","affiliation":[{"name":"6Massachusetts General Hospital Cancer Center;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Connelly","sequence":"additional","affiliation":[{"name":"7The Ohio State University Comprehensive Cancer Center - 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