{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T02:40:00Z","timestamp":1793155200172,"version":"4.5.0"},"reference-count":36,"publisher":"Harborside Press, LLC","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Trends in diagnostic biopsy sample collection approaches for primary bone sarcomas have shifted in the past 2 decades. Although open\/incisional biopsies used to be the predominant approach to obtain diagnostic material for Ewing sarcoma and osteosarcoma, image-guided core needle biopsies have increased in frequency and are safe for patients. These procedures are less invasive and reduce recovery times but have potential limitations. The quantity and quality of tissue obtained through these procedures vary between institutions. Acquired viable tissue volumes can be low, limiting the conduct of downstream expanded clinical workup, molecular analyses, and research. Patients with advanced Ewing sarcoma and osteosarcoma continue to have overall poor outcomes despite dose-intensive cytotoxic chemotherapy. The biology of treatment resistance is not currently well understood, partly due to limited availability of relevant tissue to study. There is a need for access to quality tumor specimens for molecular and other analyses to identify high-risk tumor subsets and drive discovery to improve patient outcomes. Given broad variability in bone tumor tissue procurement and processing across member institutions, the Children\u2019s Oncology Group Bone Tumor Committee convened a multidisciplinary group of experts to outline the current and near-future tissue needs for optimal clinical care and access to research platforms. The goal of this working group was to provide high-level guidance on biopsy practices that safely meet these evolving needs. Harmonizing tissue collection practices is paramount to improving the care of children, adolescents, and young adults diagnosed with Ewing sarcoma and osteosarcoma.<\/jats:p>","DOI":"10.6004\/jnccn.2024.7063","type":"journal-article","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T14:55:22Z","timestamp":1735311322000},"source":"Crossref","is-referenced-by-count":12,"title":["Optimizing Ewing Sarcoma and Osteosarcoma Biopsy Acquisition: A Children\u2019s Oncology Group Bone Tumor Committee Consensus Statement"],"prefix":"10.6004","volume":"23","author":[{"given":"Matthew S.","family":"Dietz","sequence":"first","affiliation":[{"name":"University of Utah and Primary Children\u2019s Hospital, Salt Lake City, UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyaa","family":"Al-Ibraheemi","sequence":"additional","affiliation":[{"name":"Boston Children\u2019s Hospital, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica L.","family":"Davis","sequence":"additional","affiliation":[{"name":"Indiana University, Indianapolis, IN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Matthew","family":"Hawkins","sequence":"additional","affiliation":[{"name":"Emory University School of Medicine, Department of Radiology and Imaging Sciences, Children\u2019s Healthcare of Atlanta, Atlanta, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian T.","family":"Craig","sequence":"additional","affiliation":[{"name":"Children\u2019s Wisconsin, Medical College of Wisconsin, Milwaukee, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshni","family":"Dasgupta","sequence":"additional","affiliation":[{"name":"University of Cincinnati, Department of Surgery, Cincinnati Children\u2019s, Cincinnati, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Geller","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital at Montefiore, Montefiore Medical Center, The University Hospital for Albert Einstein College of Medicine, Bronx, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Shulman","sequence":"additional","affiliation":[{"name":"Dana-Farber\/Boston Children\u2019s Cancer and Blood Disorders Center, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Cohen-Gogo","sequence":"additional","affiliation":[{"name":"The Hospital for Sick Children, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Gupta","sequence":"additional","affiliation":[{"name":"Division of Pediatric Oncology, Department of Pediatrics, Roswell Park Comprehensive Cancer Center, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan L.","family":"Whiteway","sequence":"additional","affiliation":[{"name":"Walter Reed National Military Medical Center, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily K.","family":"Slotkin","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center, New York, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine M.","family":"Heske","sequence":"additional","affiliation":[{"name":"Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safia K.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Mayo Clinic Arizona, Phoenix, AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Indelicato","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University of Florida, Gainesville, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine M.","family":"Albert","sequence":"additional","affiliation":[{"name":"Ben Towne Center for Childhood Cancer Research, Seattle Children\u2019s Hospital, Seattle, WA"},{"name":"Department of Pediatrics, University of Washington, Seattle, WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Montgomery","sequence":"additional","affiliation":[{"name":"Texas Children\u2019s Hospital, Baylor College of Medicine, Houston, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse K.","family":"Sandberg","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Lucile Packard Children\u2019s Hospital, Stanford University, Stanford, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holcombe E.","family":"Grier","sequence":"additional","affiliation":[{"name":"Dana-Farber\/Boston Children\u2019s Cancer and Blood Disorders Center, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Krailo","sequence":"additional","affiliation":[{"name":"Department of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Isakoff","sequence":"additional","affiliation":[{"name":"Center for Cancer and Blood Disorders, Connecticut Children\u2019s Medical Center, Hartford, CT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elyssa","family":"Rubin","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital of Orange County, Orange, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth R.","family":"Lawlor","sequence":"additional","affiliation":[{"name":"Ben Towne Center for Childhood Cancer Research, Seattle Children\u2019s Hospital, Seattle, WA"},{"name":"Department of Pediatrics, University of Washington, Seattle, WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven G.","family":"DuBois","sequence":"additional","affiliation":[{"name":"Dana-Farber\/Boston Children\u2019s Cancer and Blood Disorders Center, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo","family":"Mascarenhas","sequence":"additional","affiliation":[{"name":"Cedars-Sinai Medical Center, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"Grohar","sequence":"additional","affiliation":[{"name":"Center for Childhood Cancer Research, Children\u2019s Hospital of Philadelphia, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odion","family":"Binitie","sequence":"additional","affiliation":[{"name":"Moffitt Cancer Center, Tampa, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damon","family":"Reed","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center, New York, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Janeway","sequence":"additional","affiliation":[{"name":"Dana-Farber\/Boston Children\u2019s Cancer and Blood Disorders Center, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan D.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Nationwide Children\u2019s Hospital, Columbus, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly M.","family":"Bailey","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4047","reference":[{"key":"B1","series-title":"NPJ Precis Oncol","first-page":"65.","article-title":"An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma","volume":"6","author":"Shulman DS","year":"2022","unstructured":"Shulman DS, Whittle SB, Surdez D,  An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma. NPJ Precis Oncol 2022;6:65."},{"key":"B2","series-title":"J Clin Oncol","first-page":"3685","article-title":"Age dependency of the prognostic impact of tumor genomics in localized resectable MYCN-nonamplified neuroblastomas. Report from the SIOPEN Biology Group on the LNESG trials and a COG validation group","volume":"38","author":"Ambros IM","year":"2020","unstructured":"Ambros IM, Tonini GP, P\u00f6tschger U,  Age dependency of the prognostic impact of tumor genomics in localized resectable MYCN-nonamplified neuroblastomas. Report from the SIOPEN Biology Group on the LNESG trials and a COG validation group. J Clin Oncol 2020;38:3685\u20133697."},{"key":"B3","series-title":"J Clin Oncol","first-page":"2769","article-title":"Augmentation of therapy for combined loss of heterozygosity 1p and 16q in favorable histology Wilms tumor: a Children\u2019s Oncology Group AREN0532 and AREN0533 study report","volume":"37","author":"Dix DB","year":"2019","unstructured":"Dix DB, Fernandez CV, Chi YY,  Augmentation of therapy for combined loss of heterozygosity 1p and 16q in favorable histology Wilms tumor: a Children\u2019s Oncology Group AREN0532 and AREN0533 study report. J Clin Oncol 2019;37:2769\u20132777."},{"key":"B4","series-title":"N Engl J Med","first-page":"731","article-title":"Efficacy of larotrectinib in TRK fusion-positive cancers in adults and children","volume":"378","author":"Drilon A","year":"2018","unstructured":"Drilon A, Laetsch TW, Kummar S,  Efficacy of larotrectinib in TRK fusion-positive cancers in adults and children. N Engl J Med 2018;378:731\u2013739."},{"key":"B5","series-title":"Lancet Oncol","first-page":"531","article-title":"Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1\/2 clinical trials","volume":"21","author":"Hong DS","year":"2020","unstructured":"Hong DS, DuBois SG, Kummar S,  Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1\/2 clinical trials. Lancet Oncol 2020;21:531\u2013540."},{"key":"B6","series-title":"J Clin Oncol","first-page":"3229","article-title":"Revised neuroblastoma risk classification system: a report from the Children\u2019s Oncology Group","volume":"39","author":"Irwin MS","year":"2021","unstructured":"Irwin MS, Naranjo A, Zhang FF,  Revised neuroblastoma risk classification system: a report from the Children\u2019s Oncology Group. J Clin Oncol 2021;39:3229\u20133241."},{"key":"B7","series-title":"JCO Precis Oncol","first-page":"PO.18.00297","article-title":"Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors","volume":"3","author":"Trahair T","year":"2019","unstructured":"Trahair T, Gifford AJ, Fordham A,  Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors. JCO Precis Oncol 2019;3:PO.18.00297."},{"key":"B8","series-title":"Histopathology","first-page":"531","article-title":"Datasets for the reporting of primary tumour in bone: recommendations from the International Collaboration on Cancer Reporting (ICCR)","volume":"82","author":"Bov\u00e9e JVMG","year":"2023","unstructured":"Bov\u00e9e JVMG, Webster F, Amary F,  Datasets for the reporting of primary tumour in bone: recommendations from the International Collaboration on Cancer Reporting (ICCR). Histopathology 2023;82:531\u2013540."},{"key":"B9","series-title":"Ann Oncol","first-page":"1520","article-title":"Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan clinical practice guideline for diagnosis, treatment and follow-up","volume":"32","author":"Strauss SJ","year":"2021","unstructured":"Strauss SJ, Frezza AM, Abecassis N,  Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan clinical practice guideline for diagnosis, treatment and follow-up. Ann Oncol 2021;32:1520\u20131536."},{"key":"B10","article-title":"NCCN Clinical Practice Guidelines in Oncology: Bone Cancer","author":"Biermann JS","unstructured":"Biermann JS, Hirbe A, Ahlawat S,  NCCN Clinical Practice Guidelines in Oncology: Bone Cancer. Version 1.2025. For the most recent version, visit https:\/\/www.nccn.org"},{"key":"B11","series-title":"J Adolesc Young Adult Oncol","first-page":"141","article-title":"Who treats adolescents and young adults with cancer? A report from the AYA HOPE study","volume":"4","author":"Parsons HM","year":"2015","unstructured":"Parsons HM, Harlan LC, Schmidt S,  Who treats adolescents and young adults with cancer? A report from the AYA HOPE study. J Adolesc Young Adult Oncol 2015;4:141\u2013150."},{"key":"B12","series-title":"J Bone Joint Surg Am","first-page":"656","article-title":"The hazards of the biopsy, revisited. Members of the Musculoskeletal Tumor Society","volume":"78","author":"Mankin HJ","year":"1996","unstructured":"Mankin HJ, Mankin CJ, Simon MA. The hazards of the biopsy, revisited. Members of the Musculoskeletal Tumor Society. J Bone Joint Surg Am 1996;78:656\u2013663."},{"key":"B13","series-title":"Ann Surg Oncol","first-page":"3658","article-title":"Pediatric and young adult image-guided percutaneous bone biopsy-a new standard of care?","volume":"30","author":"Cooke-Barber J","year":"2023","unstructured":"Cooke-Barber J, Brungardt JG, Sorger M,  Pediatric and young adult image-guided percutaneous bone biopsy-a new standard of care? Ann Surg Oncol 2023;30:3658\u20133665."},{"key":"B14","series-title":"J Clin Oncol","article-title":"A report on the review of archived osteosarcoma and EWING sarcoma specimens at the Biopathology Center, BONE Sarcoma Committee, Children\u2019s Oncology Group","volume":"40","author":"Chen S","year":"2022","unstructured":"Chen S, Shenoy A, Al-Ibraheemi A,  A report on the review of archived osteosarcoma and EWING sarcoma specimens at the Biopathology Center, BONE Sarcoma Committee, Children\u2019s Oncology Group. J Clin Oncol 2022;40(Suppl):Abstract 11524."},{"key":"B15","series-title":"Clin Cancer Res","first-page":"3395","article-title":"Biological sample collection to advance research and treatment: a Fight Osteosarcoma Through European Research (FOSTER) and Euro Ewing Consortium (EEC) statement","volume":"30","author":"Green D","year":"2024","unstructured":"Green D, van Ewijk R, Tirtei E,  Biological sample collection to advance research and treatment: a Fight Osteosarcoma Through European Research (FOSTER) and Euro Ewing Consortium (EEC) statement. Clin Cancer Res 2024;30:3395\u20133406."},{"key":"B16","series-title":"Cancer","first-page":"1917","article-title":"Core needle biopsy versus incisional biopsy for differentiation of soft-tissue sarcomas: a systematic review and meta-analysis","volume":"126","author":"Birgin E","year":"2020","unstructured":"Birgin E, Yang C, Hetjens S,  Core needle biopsy versus incisional biopsy for differentiation of soft-tissue sarcomas: a systematic review and meta-analysis. Cancer 2020;126:1917\u20131928."},{"key":"B17","series-title":"Eur J Med Res","first-page":"29.","article-title":"Percutaneous core needle biopsy versus open biopsy in diagnostics of bone and soft tissue sarcoma: a retrospective study","volume":"17","author":"Pohlig F","year":"2012","unstructured":"Pohlig F, Kirchhoff C, Lenze U,  Percutaneous core needle biopsy versus open biopsy in diagnostics of bone and soft tissue sarcoma: a retrospective study. Eur J Med Res 2012;17:29."},{"key":"B18","series-title":"Clin Orthop Relat Res","first-page":"891","article-title":"Adult soft tissue sarcoma local recurrence after adjuvant treatment without resection of core needle biopsy tract","volume":"471","author":"Binitie O","year":"2013","unstructured":"Binitie O, Tejiram S, Conway S,  Adult soft tissue sarcoma local recurrence after adjuvant treatment without resection of core needle biopsy tract. Clin Orthop Relat Res 2013;471:891\u2013898."},{"key":"B19","series-title":"AJR Am J Roentgenol","first-page":"523","article-title":"Bone biopsies: what radiologists need to know","volume":"215","author":"Tomasian A","year":"2020","unstructured":"Tomasian A, Hillen TJ, Jennings JW. Bone biopsies: what radiologists need to know. AJR Am J Roentgenol 2020;215:523\u2013533."},{"key":"B20","series-title":"Diagnostics (Basel)","first-page":"1552","article-title":"Percutaneous core needle biopsy can efficiently and safely diagnose most primary bone tumors","volume":"11","author":"Crenn V","year":"2021","unstructured":"Crenn V, Vezole L, Bouhamama A,  Percutaneous core needle biopsy can efficiently and safely diagnose most primary bone tumors. Diagnostics (Basel) 2021;11:1552."},{"key":"B21","series-title":"J Pediatr Hematol Oncol","first-page":"337","article-title":"Image-guided percutaneous core needle biopsy of musculoskeletal tumors in children","volume":"36","author":"Mitton B","year":"2014","unstructured":"Mitton B, Seeger LL, Eckardt MA,  Image-guided percutaneous core needle biopsy of musculoskeletal tumors in children. J Pediatr Hematol Oncol 2014;36:337\u2013341."},{"key":"B22","series-title":"Skeletal Radiol","first-page":"138","article-title":"CT-guided percutaneous core needle biopsy in deep seated musculoskeletal lesions: a prospective study of 128 cases","volume":"35","author":"Puri A","year":"2006","unstructured":"Puri A, Shingade VU, Agarwal MG,  CT-guided percutaneous core needle biopsy in deep seated musculoskeletal lesions: a prospective study of 128 cases. Skeletal Radiol 2006;35:138\u2013143."},{"key":"B23","series-title":"Arch Pathol Lab Med","first-page":"107","article-title":"The pathologic diagnosis of pediatric soft tissue tumors in the era of molecular medicine: the Sarcoma Pediatric Pathology Research Interest Group perspective","volume":"148","author":"Black JO","year":"2024","unstructured":"Black JO, Al-Ibraheemi A, Arnold MA,  The pathologic diagnosis of pediatric soft tissue tumors in the era of molecular medicine: the Sarcoma Pediatric Pathology Research Interest Group perspective. Arch Pathol Lab Med 2024;148:107\u2013116."},{"key":"B24","series-title":"Radiology","first-page":"962","article-title":"Bone and soft-tissue lesions: what factors affect diagnostic yield of image-guided core-needle biopsy?","volume":"248","author":"Wu JS","year":"2008","unstructured":"Wu JS, Goldsmith JD, Horwich PJ,  Bone and soft-tissue lesions: what factors affect diagnostic yield of image-guided core-needle biopsy? Radiology 2008;248:962\u2013970."},{"key":"B25","series-title":"Arch Pathol Lab Med","first-page":"678","article-title":"Optimal diagnostic yield achieved with on-site pathology evaluation of fine-needle aspiration- assisted core biopsies for pediatric osseous lesions: a single-center experience","volume":"141","author":"Patel K","year":"2017","unstructured":"Patel K, Kinnear D, Quintanilla NM,  Optimal diagnostic yield achieved with on-site pathology evaluation of fine-needle aspiration- assisted core biopsies for pediatric osseous lesions: a single-center experience. Arch Pathol Lab Med 2017;141:678\u2013683."},{"key":"B26","series-title":"J Vasc Interv Radiol","first-page":"623","article-title":"Image-guided percutaneous needle biopsy for benign and malignant bone tumors: systematic review and meta-analysis","volume":"34","author":"Ferreira FBMD","year":"2023","unstructured":"Ferreira FBMD, Puchnick A, Garcia DL,  Image-guided percutaneous needle biopsy for benign and malignant bone tumors: systematic review and meta-analysis. J Vasc Interv Radiol 2023;34:623\u2013632.e2."},{"key":"B27","series-title":"Muscle Nerve","first-page":"688","article-title":"A well-tolerated core needle muscle biopsy process suitable for children and adults","volume":"62","author":"Barthelemy F","year":"2020","unstructured":"Barthelemy F, Woods JD, Nieves-Rodriguez S,  A well-tolerated core needle muscle biopsy process suitable for children and adults. Muscle Nerve 2020;62:688\u2013698."},{"key":"B28","series-title":"Tech Vasc Interv Radiol","first-page":"100779.","article-title":"Percutaneous core needle biopsy: considerations in the pediatric patient","volume":"24","author":"Hesh CA","year":"2021","unstructured":"Hesh CA, Gill AE. Percutaneous core needle biopsy: considerations in the pediatric patient. Tech Vasc Interv Radiol 2021;24:100779."},{"key":"B29","series-title":"J Bone Joint Surg Am","first-page":"103","article-title":"Vacuum-assisted minimally invasive biopsy of soft-tissue tumors","volume":"94","author":"Mohr Z","year":"2012","unstructured":"Mohr Z, Hirche C, Klein T,  Vacuum-assisted minimally invasive biopsy of soft-tissue tumors. J Bone Joint Surg Am 2012;94:103\u2013109."},{"key":"B30","series-title":"Cancer Cytopathol","first-page":"449","article-title":"Specimen acquisition: ROSEs, gardeners, and gatekeepers","volume":"125","author":"Kraft AO","year":"2017","unstructured":"Kraft AO. Specimen acquisition: ROSEs, gardeners, and gatekeepers. Cancer Cytopathol 2017;125:449\u2013454."},{"key":"B31","article-title":"NCI best practices for biospecimen resources","author":"National Cancer Institute","unstructured":"National Cancer Institute. NCI best practices for biospecimen resources. Accessed May 1, 2024. Available at: https:\/\/biospecimens.cancer.gov\/bestpractices\/2016-NCIBestPractices.pdf"},{"key":"B32","series-title":"Front Oncol","first-page":"19.","article-title":"Establishing and maintaining an extensive library of patient-derived xenograft models","volume":"8","author":"Mattar M","year":"2018","unstructured":"Mattar M, McCarthy CR, Kulick AR,  Establishing and maintaining an extensive library of patient-derived xenograft models. Front Oncol 2018;8:19."},{"key":"B33","series-title":"Mod Pathol","first-page":"1505","article-title":"Effect of decalcification protocols on immunohistochemistry and molecular analyses of bone samples","volume":"33","author":"Miquelestorena-Standley E","year":"2020","unstructured":"Miquelestorena-Standley E, Jourdan ML, Collin C,  Effect of decalcification protocols on immunohistochemistry and molecular analyses of bone samples. Mod Pathol 2020;33:1505\u20131517."},{"key":"B34","series-title":"Blood","first-page":"4659","article-title":"Acid-based decalcification methods compromise genomic profiling from DNA and RNA","volume":"134","author":"Duncan I","year":"2019","unstructured":"Duncan I, Danziger N, Duncan D,  Acid-based decalcification methods compromise genomic profiling from DNA and RNA. Blood 2019;134:4659."},{"key":"B35","series-title":"J Clin Oncol","first-page":"2368","article-title":"Ethical framework for including research biopsies in oncology clinical trials: American Society of Clinical Oncology research statement","volume":"37","author":"Levit LA","year":"2019","unstructured":"Levit LA, Peppercorn JM, Tam AL,  Ethical framework for including research biopsies in oncology clinical trials: American Society of Clinical Oncology research statement. J Clin Oncol 2019;37:2368\u20132377."},{"key":"B36","series-title":"J Clin Oncol","first-page":"1631","article-title":"Circulating tumor DNA analysis in patients with cancer: American Society of Clinical Oncology and College of American Pathologists joint review","volume":"36","author":"Merker JD","year":"2018","unstructured":"Merker JD, Oxnard GR, Compton C,  Circulating tumor DNA analysis in patients with cancer: American Society of Clinical Oncology and College of American Pathologists joint review. J Clin Oncol 2018;36:1631\u20131641."}],"container-title":["Journal of the National Comprehensive Cancer Network"],"original-title":[],"link":[{"URL":"https:\/\/jnccn.org\/view\/journals\/jnccn\/23\/1\/article-e247063.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jnccn.org\/downloadpdf\/journals\/jnccn\/23\/1\/article-e247063.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jnccn.org\/downloadpdf\/journals\/jnccn\/23\/1\/article-e247063.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T13:55:33Z","timestamp":1736949333000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnccn.org\/view\/journals\/jnccn\/23\/1\/article-e247063.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":36,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.6004\/jnccn.2024.7063","relation":{},"ISSN":["1540-1405","1540-1413"],"issn-type":[{"value":"1540-1405","type":"print"},{"value":"1540-1413","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]}}}