{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T12:30:40Z","timestamp":1793017840525,"version":"4.5.0"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2023,10,31]]},"abstract":"<jats:p>Aflatoxin is a potent mycotoxin of Aspergillus flavus that has been classified as a Group I carcinogen. O-methyltransferase A (Omt-A) is a critical enzyme in the formation of aflatoxin. It catalyzes the methylation of norsalic acid to form the highly toxic intermediate averantin. The ligand-protein interaction of Omt-A was performed with piperlonguminin and blasticidins. The maximum affinity of -10.6 was found for the 5ICC_A piperlonguminine at site1 (X,Y,Z: -15.282, 21.785, 5.672). Compounds such as Blasticidin S, Neoeriocitrin, Blasticidin S - hydrochloric acid, 6,6''-Bigenkwanin, Pipernomaline, and Eriodictyol were found to have binding features to protein residues, as shown by computational interaction at the molecular level.<\/jats:p>","DOI":"10.6026\/97320630019990","type":"journal-article","created":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T06:11:03Z","timestamp":1699683063000},"page":"990-994","source":"Crossref","is-referenced-by-count":1,"title":["Molecular docking analysis of Omt-A protein model from Aspergillus flavus with synthetic compounds"],"prefix":"10.6026","volume":"19","author":[{"name":"Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Ajmal Ali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4070","published-online":{"date-parts":[[2023,10,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T06:11:07Z","timestamp":1699683067000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/019\/97320630019990.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,31]]},"references-count":0,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,10,31]]},"published-print":{"date-parts":[[2023,10,31]]}},"URL":"https:\/\/doi.org\/10.6026\/97320630019990","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,31]]}}}