{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T05:12:36Z","timestamp":1738559556400,"version":"3.35.0"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2024,11,30]]},"abstract":"<jats:p>The contributions of pH balance and electrolytes among patients with chronic obstructive pulmonary disease (COPD) experiencing hypercapnic exacerbations requiring non-invasive ventilation (NIV) are of interest. Hence, we used samples from 70 patients admitted in a tertiary care hospital from January to June 2023. The main variable analyzed was arterial blood gas data and serum electrolyte levels. A positive correlation between bicarbonate levels and PCO2 was found, with p &lt; 0.01 and r = 0.74, indicating metabolic compensation for respiratory acidosis. NIV was required in the majority of patients: in 64.3%, values were higher for both PCO2 (52.3 \u0105 7.1 mmHg vs. 39.6 \u0105 4.3 mmHg) and bicarbonate levels (32.4 \u0105 4.8m Eq\/L vs. 26.1 \u0105 3.1 m Eq\/L; p &lt; 0.01) in the NIV group. Thus, data highlights the role of monitoring PCO2 and bicarbonate in guiding the use of NIV and in a more secondary role to hypercapnia disturbances in electrolytes.<\/jats:p>","DOI":"10.6026\/9732063002001503","type":"journal-article","created":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T10:07:43Z","timestamp":1738490863000},"page":"1503-1507","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of pH, electrolytes and non-invasive respiratory support in COPD with elevated CO2"],"prefix":"10.6026","volume":"20","author":[{"name":"Shadan Institute of Medical Sciences, Teaching Hospital and Research Centre, Hyderabad, India","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madeeha","family":"Hussaini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rida","family":"Minhaj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Deccan college of Medical Sciences, Hyderabad, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nukala","family":"Aishwarya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Prathima Institute of Medical Sciences, Karimnagar, Telangana, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maanasa","family":"Kurapati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Kamineni Institute of Medical Sciences, Narketpally, Telangana, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yazan","family":"Al Khatib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Al Faisal University, Riyadh, Saudi Arabia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zehra","family":"Yousuf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Deccan college of Medical Sciences, Hyderabad, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamedelfatihmusaab","family":"Ibrahim Mohamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"National Ribat University, Khartoum, Sudan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rabia","family":"Azam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Quetta Institute of Medical Sciences, Quetta, Pakistan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamza A","family":"Orfali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Al Neelain University, Khartoum, Sudan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Abdul Mateen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Shadan Institute of Medical Sciences, Teaching Hospital and Research Centre, Hyderabad, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2024,11,30]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T10:07:57Z","timestamp":1738490877000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/020\/9732063002001503.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,30]]},"references-count":0,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11,30]]},"published-print":{"date-parts":[[2024,11,30]]}},"URL":"https:\/\/doi.org\/10.6026\/9732063002001503","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,30]]}}}