{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T04:54:54Z","timestamp":1770958494096,"version":"3.50.1"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2025,5,31]]},"abstract":"<jats:p>The clinical profile, risk factors, diagnostic methods, therapeutic interventions and outcomes of post-COVID rhino-orbital cerebral mucormycosis (ROCM) cases in a tertiary care center in Eastern India is of interest.  This prospective study included 102 post-COVID patients diagnosed with rhino-orbital cerebral mucormycosis over one year at a tertiary care center. Clinical data, imaging, microbiological findings, treatments and outcomes were recorded. All patients received antifungal therapy, with surgical intervention as needed.  Out of 102 post-COVID patients diagnosed with rhino-orbital cerebral mucormycosis, 79.4% had diabetes mellitus and 85.3% had a history of corticosteroid use. Orbital involvement was seen in 74.5% of patients, with cerebral extension in 33.3%. Surgical intervention was required in 76.4% of cases and the overall mortality rate was 18.6%. Post-COVID mucormycosis is a rapidly progressive and life-threatening infection strongly associated with diabetes and corticosteroid use. Early diagnosis, prompt antifungal therapy and timely surgical intervention are critical for improving outcomes.<\/jats:p>","DOI":"10.6026\/973206300211290","type":"journal-article","created":{"date-parts":[[2025,7,5]],"date-time":"2025-07-05T14:17:58Z","timestamp":1751725078000},"page":"1290-1294","source":"Crossref","is-referenced-by-count":2,"title":["Post Covid rhino - Orbital cerebral mucormycosis among Indian patients"],"prefix":"10.6026","volume":"21","author":[{"name":"Department of Pathology, IGIMS, Patna, Bihar, India","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rashmi Rani","family":"Bharti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kshiti","family":"Atreya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Pathology, IGIMS, Patna, Bihar, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kumari","family":"Sunny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Pathology, IGIMS, Patna, Bihar, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Radiodiagnosis, IGIMS, Patna, Bihar, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bharti","family":"Kumari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Pathology, IGIMS, Patna, Bihar, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2025,5,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2025,7,5]],"date-time":"2025-07-05T14:17:59Z","timestamp":1751725079000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/021\/973206300211290.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,31]]},"references-count":0,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2025,5,31]]},"published-print":{"date-parts":[[2025,5,31]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300211290","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,31]]}}}