{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T04:39:24Z","timestamp":1785904764172,"version":"3.56.0"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2025,6,30]]},"abstract":"<jats:p>Tuberculosis (TB) remains a common and serious opportunistic infection among HIV-infected individuals, with clinical presentation closely tied to immune status. In this prospective study of 100 HIV-positive patients with TB, pulmonary TB predominated in those with CD4 counts &gt;200, while extrapulmonary and disseminated TB were strongly associated with CD4 counts &lt;200. Symptoms such as cough and fever were prevalent and radiographic findings varied with immune suppression levels. CD4 counts served as a critical marker in determining the clinical spectrum and severity of TB. These findings underscore the importance of CD4-based assessment in guiding timely diagnosis and targeted management of TB in HIV patients.<\/jats:p>","DOI":"10.6026\/973206300211602","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T14:31:54Z","timestamp":1751466714000},"page":"1602-1605","source":"Crossref","is-referenced-by-count":1,"title":["Clinical spectrum of tuberculosis among HIV infected patients in India: Correlation with immunological status using CD4 counts"],"prefix":"10.6026","volume":"21","author":[{"name":"Department of General Medicine, ESIC Medical College, Sanathnagar, Hyderabad-500038, India","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Snigdha","family":"M.K.","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padma Theja","family":"Krishnavajhala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavani","family":"Kondeti Ganga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dara","family":"Chennakesavulu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paloju","family":"Pranavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimma","family":"Shiva Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of General Medicine, ESIC Medical College, Sanathnagar, Hyderabad-500038, India","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4070","published-online":{"date-parts":[[2025,6,30]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T14:31:55Z","timestamp":1751466715000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/021\/973206300211602.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,30]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2025,6,30]]},"published-print":{"date-parts":[[2025,6,30]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300211602","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,30]]}}}