{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T01:42:50Z","timestamp":1755222170043,"version":"3.43.0"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2025,7,31]]},"abstract":"<jats:p>Vitamin D has immuno-modulatory and potential cartilage-regenerative effects. Therefore, it is of interest to evaluate the association between serum vitamin D levels, pro-inflammatory cytokines (IL-6, TNF-\u03b1), and functional status in patients with knee osteoarthritis (OA). In this cross-sectional analysis of 84 patients with bilateral knee OA, serum vitamin D, IL-6, TNF-\u03b1 levels and WOMAC scores were recorded. Patients with vitamin D deficiency exhibited significantly higher IL-6 and TNF-\u03b1 levels and worse WOMAC scores. Data shows that vitamin D deficiency is associated with increased inflammation and poorer functional outcomes in knee OA.<\/jats:p>","DOI":"10.6026\/973206300211791","type":"journal-article","created":{"date-parts":[[2025,8,10]],"date-time":"2025-08-10T06:40:21Z","timestamp":1754808021000},"page":"1791-1795","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of WOMAC index for knee osteoarthritis and its association with serum vitamin - D and serum cytokine profile"],"prefix":"10.6026","volume":"21","author":[{"name":"Department of Orthopaedic Surgery, King George's Medical University, Lucknow, India","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak","family":"Kumar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mithilesh","family":"Kannaujiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shailendra","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeev","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shah","family":"Waliullah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sujeet Kumar","family":"Chaudhary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashish","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Orthopaedic Surgery, King George's Medical University, Lucknow, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2025,7,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2025,8,10]],"date-time":"2025-08-10T06:40:22Z","timestamp":1754808022000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/021\/973206300211791.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,31]]},"references-count":0,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2025,7,31]]},"published-print":{"date-parts":[[2025,7,31]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300211791","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,31]]}}}