{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T08:03:32Z","timestamp":1792742612020,"version":"4.5.0"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2025,7,31]]},"abstract":"<jats:p>Latent Tuberculosis Infection (LTBI) is a sustained immune response to Mycobacterium tuberculosis without clinical evidence of active disease, representing a substantial reservoir, contributes to the global burden of tuberculosis (TB). To address these gaps, Cy-Tb test (formerly C-Tb), developed by the Serum Institute of India, Pune, has been introduced under NTEP policy, combines the operational simplicity of TST with the specificity of IGRAs, expanded the coverage of high-risk groups and household contacts of pulmonary TB patients. Cy-Tb represents a next-generation LTBI diagnostic solution that supports early detection, operational alignment with point-of-care testing, cost-effectiveness, integration potential into national programs and contributes significantly towards the goal of TB elimination in India by 2025 and globally by 2035.<\/jats:p>","DOI":"10.6026\/973206300212218","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T12:35:42Z","timestamp":1754915742000},"page":"2218-2220","source":"Crossref","is-referenced-by-count":7,"title":["CY-TB skin test: Detect and defeat"],"prefix":"10.6026","volume":"21","author":[{"name":"Department of Community and Family Medicine, AIIMS Bhopal, Madhya Pradesh, India","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditi","family":"Bharti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tej Pratap","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Community Medicine, Sukh Sagar Medical College and Hospital, Jabalpur, Madhya Pradesh, India","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4070","published-online":{"date-parts":[[2025,7,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T12:35:43Z","timestamp":1754915743000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/021\/973206300212218.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,31]]},"references-count":0,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2025,7,31]]},"published-print":{"date-parts":[[2025,7,31]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300212218","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,31]]}}}