{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T20:39:59Z","timestamp":1757623199085,"version":"3.44.0"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2025,8,31]]},"abstract":"<jats:p>Non-alcoholic fatty liver disease (NAFLD) is increasingly recognized as a hepatic manifestation of metabolic dysfunction, with emerging evidence linking it to thyroid abnormalities. In this case-control study of 120 adults, thyroid dysfunction was more prevalent in NAFLD cases, with 20% having overt hypothyroidism and 5% subclinical hypothyroidism. Thyroid dysfunction increased with NAFLD severity, with overt hypothyroidism observed in 66.7% of Grade 3 cases. These findings highlight a strong association between worsening thyroid function and NAFLD severity, suggesting the need for routine thyroid screening in NAFLD management.<\/jats:p>","DOI":"10.6026\/973206300212453","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T04:08:46Z","timestamp":1757390926000},"page":"2453-2458","source":"Crossref","is-referenced-by-count":0,"title":["Thyroid dysfunction in non-alcoholic fatty liver disease: A case-control study"],"prefix":"10.6026","volume":"21","author":[{"name":"Department of General Medicine, Dr. Kiran C Patel Medical College and Research Institute, Bharuch, Gujarat, India","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harshit","family":"Malkan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhavita","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Biochemistry, Dr. Kiran C Patel Medical College and Research institute, Bharuch, Gujarat, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahesh","family":"G Solu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of General Medicine, Dr. Kiran C Patel Medical College and Research Institute, Bharuch, Gujarat, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tejas","family":"D. Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Orthopaedic Surgery, Dr. Kiran C Patel Medical College & Research Institute, Bharuch, Gujarat, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahammed Kaif Mubrakhusen","family":"Bhaniya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Trauma Centre, Dr Kiran C Patel Medical College and Research institute, Bharuch, Gujarat, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2025,8,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T04:08:48Z","timestamp":1757390928000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/021\/973206300212453.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,31]]},"references-count":0,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2025,8,31]]},"published-print":{"date-parts":[[2025,8,31]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300212453","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,31]]}}}