{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:48:09Z","timestamp":1790815689719,"version":"4.1.0"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2025,9,30]]},"abstract":"<jats:p>Iron deficiency anemia in children is commonly managed with oral iron supplements, but liquid formulations are often associated with undesirable tooth staining. This in vitro study evaluated enamel discoloration on primary teeth after exposure to ferrous sulfate and iron polymaltose complex. Sixty extracted primary anterior teeth were divided into three groups and immersed daily for 21 days; with color change measured using a spectrophotometer and stereomicroscopy. Ferrous sulfate caused the highest degree of staining (\u0394E = 12.6), followed by iron polymaltose (\u0394E = 6.3), while controls showed minimal change (\u0394E = 1.2). Ferrous sulfate was associated with significantly greater enamel staining, highlighting the need to prefer low-staining formulations to improve pediatric compliance and aesthetics.<\/jats:p>","DOI":"10.6026\/973206300212980","type":"journal-article","created":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T06:17:16Z","timestamp":1759645036000},"page":"2980-2983","source":"Crossref","is-referenced-by-count":2,"title":["Evaluate enamel surface staining due to iron supplements on primary teeth - An in vitro study"],"prefix":"10.6026","volume":"21","author":[{"name":"Department of Oral Pathology & Microbiology, People's Dental Academy, People's University, Bhopal, Madhya Pradesh, India","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anish Ashok","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Dentistry, Amaltas Institute of Medical Sciences, Dewas, Madhya Pradesh, India","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimple Kishan","family":"Tirale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Pediatric & Preventive Dentistry, Rungta College of Dental Sciences & Research, Rungta Knowledge City, Kurud Road, Kohka, Bhilai, Chhattisgarh, India","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramakrishna","family":"Surada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Conservative Dentistry and Endodontics, Gitam Dental College and Hospital, Visakhapatnam, Andhra Pradesh, India","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udita","family":"Samanta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Pediatrics and Preventive Dentistry, Divya Jyoti College of dental science and Research, Modinagar, Ghaziabad, Uttar Pradesh, India","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananya","family":"Bhargava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Dentistry, Ruxmaniben deepchand gardi medical college, Ujjain, Madhya Pradesh, India","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miral","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Pediatric and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4070","published-online":{"date-parts":[[2025,9,30]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T06:17:18Z","timestamp":1759645038000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/021\/973206300212980.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":0,"journal-issue":{"issue":"09","published-online":{"date-parts":[[2025,9,30]]},"published-print":{"date-parts":[[2025,9,30]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300212980","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,30]]}}}