{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T00:27:35Z","timestamp":1759796855258,"version":"build-2065373602"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2025,9,30]]},"abstract":"<jats:p>The frequencies and contributing factors to bleeding complications among atrial fibrillation patients on a regimen of long-term oral anticoagulants is of interest. The medical records for 142 patients treated with either warfarin or direct oral anticoagulants (DOACs) were assessed over a period of three years. Major and minor bleeding episodes were associated with instability of the international normalized ratio (INR), the type of anticoagulant medication, and individual patient characteristics. The bleeding complications were observed to occur more frequently with patients presenting with unstable INR values and those treated with warfarin in contrast to DOACs patients. Thus, the importance of a tailored anticoagulation regimen to address bleeding complications in atrial fibrillation is shown.<\/jats:p>","DOI":"10.6026\/973206300213417","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T09:47:22Z","timestamp":1759744042000},"page":"3417-3419","source":"Crossref","is-referenced-by-count":0,"title":["Retrospective cohort study on long-term anticoagulation therapy for bleeding complications among atrial fibrillation patients"],"prefix":"10.6026","volume":"21","author":[{"name":"Department of Internal Medicine, Queen Elizabeth Queen Mother Hospital, Margate, United Kingdom","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megha","family":"Joy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bethamcherla Bala","family":"Chandrudu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Medical Physiology, Visvabharathi Medical College and General Hospital, Penchikalapadu, Andhra Pradesh, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Thoufeek Hussain Amjat","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Vascular Surgery, Apollo main hospital, Karpaga Vinayaga Institute of medical science and research center, Tamil Nadu, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Fleming","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Fleming","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of General Medicine, Snehadaan Hospital, Bengaluru, Karnataka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harish Sidharth","family":"Veerachamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of General Medicine, Tirunelveli Medical College, Tamil Nadu, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2025,9,30]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T09:47:24Z","timestamp":1759744044000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/021\/973206300213417.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":0,"journal-issue":{"issue":"09","published-online":{"date-parts":[[2025,9,30]]},"published-print":{"date-parts":[[2025,9,30]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300213417","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,30]]}}}