{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:30:43Z","timestamp":1768350643152,"version":"3.49.0"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2025,12,15]]},"abstract":"<jats:p>COVID-19 is frequently associated with cardiovascular complications, with cardiac troponin I (cTnI) and CK-MB serving as markers of myocardial injury. Therefore, it is of interest to analyse of medical records from 300 PCR-confirmed COVID-19 patients admitted to High Dependency Unit (HDU) and Intensive Care Unit (ICU) during the second wave (2020-2021), biomarker levels at admission were correlated with disease severity. All patients included were seriously ill but survived. Severe cases had significantly higher cTnI and CK-MB levels (p &lt; 0.001). These biomarkers provide important early prognostic information For the purpose of risk assessment and therapeutic treatment of COVID-19.<\/jats:p>","DOI":"10.6026\/973206300214585","type":"journal-article","created":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T17:20:41Z","timestamp":1768324841000},"page":"4585-4588","source":"Crossref","is-referenced-by-count":0,"title":["Correlation of troponin I and CK-MB with COVID-19 severity in seriously ill patients: A retrospective analysis from medical records"],"prefix":"10.6026","volume":"21","author":[{"name":"Department of Biochemistry, Shrimant Rajmata Vijayaraje Scindia Medical College Shivpuri, Madhya Pradesh, India","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyoti","family":"Shukla","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ritesh","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of General Medicine, Shrimant Rajmata Vijayaraje Scindia Medical College Shivpuri, Madhya Pradesh, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divyansh","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of General Medicine, Shrimant Rajmata Vijayaraje Scindia Medical College Shivpuri, Madhya Pradesh, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pankaj","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nishant Singh","family":"Verma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Orthopaedics, Shrimant Rajmata Vijayaraje Scindia Medical College, Shivpuri, Madhya Pradesh, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2025,12,15]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T17:20:42Z","timestamp":1768324842000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/021\/973206300214585.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,15]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2025,12,15]]},"published-print":{"date-parts":[[2025,12,15]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300214585","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,15]]}}}