{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:29:39Z","timestamp":1770337779661,"version":"3.49.0"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,1,31]]},"abstract":"<jats:p>Oral lichen planus (OLP) is a long-term inflammatory mucocutaneous disease that has the potential of malignant transformation. Hence, it requires effective long-term therapy. It was a randomized controlled, double-blind trial comparing triamcinolone acetonide 0.1 per cent oral paste (TA) to TA once daily with oral isotretinoin 10mg daily (TA+ISO) in 70 cases (biopsy-established) of OLP of more than 12 weeks duration. The TA+ISO group showed better clinical outcomes as the means of Thongprasom scores reduced in the TA group (p&lt;0.001). TA+ISO showed more pain reduction (VAS) at 12 weeks (p&lt;0.001), improved Histopathological (74.3) TA+ISO (p=0.006) and reduced Lesion size (p&lt;0.001). TA in combination with isotretinoin is very useful as combination therapy in OLP and clinical and histopathological results are improved.<\/jats:p>","DOI":"10.6026\/973206300220201","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T12:11:53Z","timestamp":1770293513000},"page":"201-205","source":"Crossref","is-referenced-by-count":0,"title":["Triamcinolone acetate and triamcinolone-isotretinoin efficacy in oral lichen planus management: Original clinical study"],"prefix":"10.6026","volume":"22","author":[{"name":"Department of Oral Pathology & Microbiology, People's Dental Academy, People's University, Bhopal, Madhya Pradesh, India","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anish Ashok","family":"Gupta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vatchala Rani","family":"R.M.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Oral pathology and Microbiology, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prarthana","family":"G.A.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Oral medicine and Radiology, Rajarajeswari Dental College and Hospital, Bangalore, Karnataka, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vaibhavi","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Oral Medicine and Radiology, K.M. Shah Dental College and Hospital, Sumandeep Vidhyapeeth Deemed to be University, Piparia, Waghodia, Vadodara, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Tanwar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Oral and Maxillofacial Surgery, SGT University, Gurgaon, Haryana, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santosh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Periodontology & Implantology, Karnavati University, Uvarsad, Gandhinagar, Ahmedabad, Gujarat, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2026,1,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T12:11:59Z","timestamp":1770293519000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/022\/973206300220201.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,31]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,31]]},"published-print":{"date-parts":[[2026,1,31]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300220201","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,31]]}}}