{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T04:06:14Z","timestamp":1770696374178,"version":"3.49.0"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,1,31]]},"abstract":"<jats:p>Xylitol, a naturally occurring sugar alcohol, exhibits multifaceted benefits in dentistry, including inhibition of cariogenic bacteria, suppression of biofilm formation and stimulation of salivary flow. Therefore, it is of interest to review synthesizes current evidence on its role in caries prevention, periodontal therapy and management of xerostomia, candidiasis and halitosis. Clinical and public health implications have been discussed, with emphasis on optimal dosage, delivery methods and integration into preventive strategies. Emerging evidence highlights its relevance as a safe and adjunctive modality within evidence-based preventive and therapeutic protocols. Future studies should include rigorously designed randomized controlled trials and translational studies to establish standardized guidelines for integrating it into clinical practice and community-based oral health programs.<\/jats:p>","DOI":"10.6026\/973206300220588","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T09:53:53Z","timestamp":1770630833000},"page":"588-592","source":"Crossref","is-referenced-by-count":0,"title":["Multifaceted benefits of xylitol in oral health: from caries prevention to periodontal therapy"],"prefix":"10.6026","volume":"22","author":[{"name":"epartment of Dental Surgery, Kamineni Institute of Dental Sciences, Nalgonda, India","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nidhiswi","family":"Yeruva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luisana","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Dental Surgery, School of Dentistry, University of Carabobo, Naguanagua-Venezuela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melania","family":"Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Dental Surgery, School of Dentistry, University of Zulia, Maracaibo-Venezuela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anjali","family":"Aryal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Dental Surgery, City Dental College, University of Dhaka, Dhaka-Bangladesh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo Acosta","family":"Pina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Dental Surgery, School of Dentistry, University Santa Maria, Caracas-Venezuela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihriban","family":"Say\u011f\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Dental Surgery, Necmettin Erbakan University Faculty of Dentistry, Konya\/ Turkey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2026,1,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T09:53:54Z","timestamp":1770630834000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/022\/973206300220588.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,31]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1,31]]},"published-print":{"date-parts":[[2026,1,31]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300220588","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,31]]}}}