{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T23:00:17Z","timestamp":1773270017127,"version":"3.50.1"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,2,28]]},"abstract":"<jats:p>Oral submucous fibrosis (OSMF) represents a chronic, progressive, potentially malignant disorder lacking consensus on optimal management strategies for moderate clinical stages. Therefore, it is of interest to compare diode laser fibrotomy (Group A) versus intralesional dexamethasone sodium phosphate plus hyaluronidase (Group B) in 30 patients with moderate (Group II\u8702II) OSMF. Mouth opening and cheek flexibility measurements at baseline, 1, 3 and 6 months revealed statistically significant intragroup improvements in both groups (p &lt; 0.001). Intergroup analysis demonstrated significantly greater functional gains with laser fibrotomy compared to intralesional therapy (p &lt; 0.001), highlighting superior clinical efficacy. Thus, we show OSMF management by establishing diode laser fibrotomy as a minimally invasive, highly effective treatment option for moderate disease stages.<\/jats:p>","DOI":"10.6026\/973206300221239","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T07:38:45Z","timestamp":1773214725000},"page":"1239-1243","source":"Crossref","is-referenced-by-count":0,"title":["Comparative evaluation of diode laser fibrotomy versus intralesional dexamethasone plus hyaluronidase for moderate oral submucous fibrosis"],"prefix":"10.6026","volume":"22","author":[{"given":"Vani","family":"Chappidi","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, Subharti Dental College, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farah Vaqar Ahmed","family":"Momin","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dheeraj","family":"Voulligonda","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Mamata Institute of Dental Sciences, Bachupally, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naseer","family":"Mohammad","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2026,2,28]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T07:38:49Z","timestamp":1773214729000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/022\/973206300221239.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,28]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,2,28]]},"published-print":{"date-parts":[[2026,2,28]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300221239","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,28]]}}}