{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T12:11:27Z","timestamp":1775563887547,"version":"3.50.1"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,3,31]]},"abstract":"<jats:p>Paediatric functional constipation is a common functional gastrointestinal disorder that significantly impairs health-related quality of life (HRQoL), yet its psychosocial and school-related impact remains under-recognized in routine clinical assessment. Therefore, it is of interest to evaluate the health-related quality of living (HRQoL) in children with functional constipation by using verified child and parent-reported tools and compared results to healthy controls that were age-matched. A cross-sectional, clinic-based sample was analyzed using standard scoring methods and inferential statistical data to compare groups along with severity and intensity gradients. Constipation-related children showed significant lower total HRQoL and psychosocial scores as well as greater symptom burden scores than controls and had the lowest HRQoL being observed in those who suffer from frequent painful defecation as well as fecal incontinence. Thus, we show the importance of routine HRQoL assessments in conjunction with symptom evaluation to provide a comprehensive treatment plan and monitor the response to behavioral and pharmacologic treatments.<\/jats:p>","DOI":"10.6026\/973206300221310","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T11:32:02Z","timestamp":1775561522000},"page":"1310-1313","source":"Crossref","is-referenced-by-count":0,"title":["Quality of life among Indian paediatric patients suffering from constipation: An evaluative study"],"prefix":"10.6026","volume":"22","author":[{"given":"Alka Gupta","family":"Grewal","sequence":"first","affiliation":[{"name":"Department of General Surgery, ESIC Medical College & Hospital, Ludhiana, Punjab, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shashi Mauli","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, FH Medical College, Etmadpur, Agra, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitish","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pedodontics, Yamuna Institute of Dental Sciences and Research, Yamuna Nagar, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urvashi","family":"Raj","sequence":"additional","affiliation":[{"name":"Department of Pedodontics, Yamuna Institute of Dental Sciences and Research, Yamuna Nagar, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abraham","family":"George","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, St Gregorios Dental College, Cheladu, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saira","family":"George","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, St Gregorios Dental College, Chelad, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Tiwari","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heena","family":"Dixit","sequence":"additional","affiliation":[{"name":"Department of Medical Health Administration, Index Institute, Malwanchal University, Index City, Nemawar Road, Indore, Madhya Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2026,3,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T11:32:03Z","timestamp":1775561523000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/022\/973206300221310.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,31]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,3,31]]},"published-print":{"date-parts":[[2026,3,31]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300221310","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,31]]}}}