{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T12:53:02Z","timestamp":1775307182793,"version":"3.50.1"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,3,31]]},"abstract":"<jats:p>Postoperative pain following root canal procedures remains a significant clinical challenge, with on-going controversy regarding optimal single- versus multiple-visit treatment regimens for mandibular molars with symptomatic irreversible pulpitis. This study compared postoperative pain, flare-ups and analgesic consumption between single-visit (n=60) and multiple-visit (n=60) root canal therapies using standardized rotary instrumentation and warm vertical obturation in 120 matched patients. Visual Analog Scale (VAS) measurements revealed similar pain trends across both groups, peaking at 6-12 hours postoperatively with no significant differences in pain scores at any interval. Both approaches showed comparable rates of flare-ups, swelling and analgesic intake, demonstrating equivalent safety profiles and clinical outcomes. These findings advance endodontic practice by validating single-visit root canal therapy as a time-efficient alternative that maintains comparable postoperative pain control and complication rates to multiple-visit protocols.<\/jats:p>","DOI":"10.6026\/973206300221326","type":"journal-article","created":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T11:57:19Z","timestamp":1775303839000},"page":"1326-1331","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of postoperative pain following single versus multiple-visit root canal treatment: A randomised clinical trial"],"prefix":"10.6026","volume":"22","author":[{"given":"Monika","family":"Bhardwaj","sequence":"first","affiliation":[{"name":"Department of Dentistry, American International Institute of Medical Sciences, Udaipur, 313001, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhavana","family":"Koushik","sequence":"additional","affiliation":[{"name":"Department of Dentistry, American International Institute of Medical Sciences, Udaipur, 313001, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sneha","family":"Khekade","sequence":"additional","affiliation":[{"name":"Department of Dentistry, American International Institute of Medical Sciences, Udaipur, 313001, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prashanth","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Conservative and Endodontics, Srinivas Institute of Dental Sciences, Mangalore, 574146, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sazid","family":"Hussain","sequence":"additional","affiliation":[{"name":"Dental department, Sudha Medical College & Hospital, Jagpura, Kota, 325003, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niharika","family":"Gahlod","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital, Nagpur, 441110, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2026,3,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T11:57:20Z","timestamp":1775303840000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/022\/973206300221326.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,31]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2026,3,31]]},"published-print":{"date-parts":[[2026,3,31]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300221326","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,31]]}}}