{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T14:12:20Z","timestamp":1778163140822,"version":"3.51.4"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,4,30]]},"abstract":"<jats:p>Tuberculosis remains a major cause of morbidity and mortality among individuals living with HIV. Adherence to anti-tuberculosis therapy is essential for successful treatment and sputum conversion. Therefore, it is of interest to assess knowledge, attitudes and practices (KAP) regarding tuberculosis treatment among 120 HIV-positive patients receiving first-line therapy and examined their association with sputum conversion. Structured questionnaires and follow-up interviews were administered. Sputum microscopy was performed at baseline, 2 months and 6 months. The mean total KAP score was 17.3 \u00b1 3.8. Sputum conversion occurred in 78% at 2 months and 92% at 6 months. Higher KAP scores were significantly associated with earlier sputum conversion (p &lt; 0.05). Thus, we show that patient awareness and adherence behaviours are strongly associated with treatment outcomes. Structured counselling and adherence-focused interventions may improve tuberculosis control in HIV-infected populations.<\/jats:p>","DOI":"10.6026\/973206300222324","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T13:25:34Z","timestamp":1778160334000},"page":"2324-2327","source":"Crossref","is-referenced-by-count":0,"title":["Knowledge, attitude and practice in tuberculosis treatment among HIV-positive patients: Association with sputum conversion-A mixed-methods study"],"prefix":"10.6026","volume":"22","author":[{"given":"Loisen Nathan","family":"Daniel","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Best Hospital, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amirtha","family":"Manoharan","sequence":"additional","affiliation":[{"name":"Department of Medicine, Sree Balaji Medical College and Hospital, Chromepet, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anant","family":"Fulse","sequence":"additional","affiliation":[{"name":"Department of Anatomy, NKP Salve Institute of Medical Sciences & RC and Lata Mangeshkar Hospital, Nagpur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Reda","family":"Khafagy","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Essex, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhivya","family":"Mohan","sequence":"additional","affiliation":[{"name":"Department of Medicine, Aarupadai Veedu Medical College and Hospital, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aswathy","family":"T Menon","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Sree Balaji Medical College, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2026,4,30]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T13:25:43Z","timestamp":1778160343000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/022\/973206300222324.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,30]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,4,30]]},"published-print":{"date-parts":[[2026,4,30]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300222324","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,30]]}}}