{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T15:09:56Z","timestamp":1778252996023,"version":"3.51.4"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,4,30]]},"abstract":"<jats:p>Orofacial space infections pose life-threatening risks requiring urgent intervention, but trismus\/swelling hinders diagnosis. WBC\/CRP count help monitors infection. However, PCT (Procalcitonin) offers superior bacterial specificity. Therefore, it is of interest to compare PCT, CRP and WBC levels at admission, 48 h and 96 h in 40 adults with maxillofacial space infections. PCT levels declined significantly earlier (p &lt; 0.05 at admission-to-48h and 48h-to-96h) than CRP\/WBC, correlating with clinical improvement and antibiotic response. PCT's rapid normalization outperformed traditional markers in reflecting treatment efficacy amid diagnostic challenges. Thus, we document PCT as a precise biomarker for guiding antibiotic therapy and prognostication in maxillofacial infections.<\/jats:p>","DOI":"10.6026\/973206300222476","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T14:14:26Z","timestamp":1778249666000},"page":"2476-2480","source":"Crossref","is-referenced-by-count":0,"title":["Comparative assessment of total WBC and C- reactive protein counts to procalcitonin levels in subjects having maxillofacial space infection"],"prefix":"10.6026","volume":"22","author":[{"given":"Priyadershini","family":"A Rangari","sequence":"first","affiliation":[{"name":"Department of Dentistry, Nandkumar Singh Chouhan Government Medical College, Khandwa, Madhya Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neelam","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Shri Krishna Medical College Hospital, Muzaffarpur, Bihar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alisha","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Dentistry, ESIC Medical College and Hospital, Indore, Madhya Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Himani Naresh","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of ENT, Dr. Laxminarayan Pandey Government Medical College, Ratlam, Madhya Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azam","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Dental College Azamgarh, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Udaybhan","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial Surgery, R.R. Dental College & Hospital, Udaipur, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4070","published-online":{"date-parts":[[2026,4,30]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T14:14:28Z","timestamp":1778249668000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.bioinformation.net\/022\/973206300222476.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,30]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,4,30]]},"published-print":{"date-parts":[[2026,4,30]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300222476","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,30]]}}}