{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T07:02:37Z","timestamp":1779692557254,"version":"3.53.1"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,4,30]]},"abstract":"<jats:p>Diabetic peripheral neuropathy is a common and debilitating complication of diabetes mellitus, significantly impacting the quality of life of affected individuals. Vitamin B12 is essential for nerve function and myelin synthesis and its deficiency can lead to neuropathy that resembles diabetic neuropathy. Long-term metformin use in diabetic patients increases the risk of vitamin B12 deficiency, making the relationship between the two critical to explore. The study evaluated the correlation between serum vitamin B12 levels and peripheral neuropathy in type 2 diabetes patients using clinical assessments and vitamin B12 measurement through a chemiluminescent immunoassay. Thus, we show the link between vitamin B12 deficiency and severity of peripheral neuropathy in type 2 diabetes patients on long-term metformin therapy.<\/jats:p>","DOI":"10.6026\/973206300222624","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T06:04:46Z","timestamp":1779689086000},"page":"2624-2629","source":"Crossref","is-referenced-by-count":0,"title":["Correlation between vitamin B12 levels and peripheral neuropathy in diabetic patients"],"prefix":"10.6026","volume":"22","author":[{"given":"Irfan","family":"MD","sequence":"first","affiliation":[{"name":"Department of Physiology, Santosh Deemed to be University, Ghaziabad, Delhi NCR, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poonam","family":"Motwani","sequence":"additional","affiliation":[{"name":"Department of Physiology, Government Medical College (GMC), Ratlam, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritika","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Gajra Raja Medical College, Gwalior, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayakrishnan","family":"B","sequence":"additional","affiliation":[{"name":"Department of Medicine, Educare Institute of Dental Sciences, Malappuram, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parth","family":"Jani","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Government Medical College, Bhavnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario Maristhanny","family":"Garc\u00eda Ferr\u00edn","sequence":"additional","affiliation":[{"name":"Department of Medicine, Universidad Central del Ecuador, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souvik","family":"Sur","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram","family":"Rattan Negi","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, AIIMS, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4070","published-online":{"date-parts":[[2026,4,30]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T06:04:47Z","timestamp":1779689087000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/022\/973206300222624.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,30]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,4,30]]},"published-print":{"date-parts":[[2026,4,30]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300222624","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,30]]}}}