{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T06:06:00Z","timestamp":1780725960735,"version":"3.54.1"},"reference-count":0,"publisher":"Biomedical Informatics","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioinformation"],"published-print":{"date-parts":[[2026,5,31]]},"abstract":"<jats:p>Periodontal diseases, caused by pathogenic dental plaque biofilm, are often treated with chlorhexidine, but its long-term use can lead to undesirable side effects. Therefore, it is of interest to compare the antimicrobial efficacy of two herbal mouthwashes, Oralife and Ora-T, against periodontal pathogens Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans using the disc diffusion method. Results showed that Oralife exhibited significantly larger zones of inhibition than Ora-T at all tested concentrations. No inhibitory effect was observed at the lowest concentration. Thus, we show Oralife's potential as a more effective herbal alternative for periodontal therapy.<\/jats:p>","DOI":"10.6026\/973206300222823","type":"journal-article","created":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T05:50:37Z","timestamp":1780725037000},"page":"2823-2827","source":"Crossref","is-referenced-by-count":0,"title":["Concentration-dependent antimicrobial effects of two mouthwashes on key periodontal pathogens: An in vitro study"],"prefix":"10.6026","volume":"22","author":[{"given":"M.M Dayakar, Aishwarya","family":"Bruhanmath","sequence":"first","affiliation":[{"name":"Department of Periodontology, KVG Dental College and Hospital, Sullia, Karnataka, India; *Corresponding author"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash Pai Gurpur, Shivananda","family":"K Hiranya","sequence":"additional","affiliation":[{"name":"Department of Periodontology, KVG Dental College and Hospital, Sullia, Karnataka, India; *Corresponding author"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.S","family":"Shilpa","sequence":"additional","affiliation":[{"name":"Department of Periodontology, KVG Dental College and Hospital, Sullia, Karnataka, India; *Corresponding author"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vidyalakshmi","family":"S Rao","sequence":"additional","affiliation":[{"name":"Department of Periodontology, KVG Dental College and Hospital, Sullia, Karnataka, India; *Corresponding author"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarja","family":"Ishwarya","sequence":"additional","affiliation":[{"name":"Department of Periodontology, KVG Dental College and Hospital, Sullia, Karnataka, India; *Corresponding author"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4070","published-online":{"date-parts":[[2026,5,31]]},"container-title":["Bioinformation"],"original-title":[],"deposited":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T05:50:38Z","timestamp":1780725038000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.bioinformation.net\/022\/973206300222823.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,31]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,5,31]]},"published-print":{"date-parts":[[2026,5,31]]}},"URL":"https:\/\/doi.org\/10.6026\/973206300222823","relation":{},"ISSN":["0973-8894","0973-2063"],"issn-type":[{"value":"0973-8894","type":"print"},{"value":"0973-2063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,31]]}}}